Full Disclosure with James O'Brien

• Leo Varadkar: Former Prime Minister of Ireland on Power and Letting Go

  Before becoming Ireland’s youngest Taoiseach, Leo Varadkar was a Dublin GP with bold ambitions and a belief that politics could be a kind of medicine for society.In this episode of Full Disclosure, James O’Brien sits down with the former Prime Minister to explore his extraordinary rise from a mixed-heritage childhood in 1980s Ireland, to leading his country through Brexit battles, historic referendums and the turbulence of the pandemic. They discuss the unlikely path that took him from medical practice to the world stage, the emotional costs of leadership, and why he chose to step away at just 45 years old.Frank, reflective and often surprising, this is a conversation about resilience, identity, and what it really means to hold power in a changing IrelandFind out more about Leo Varadkar’s memoir Speaking My Mind here

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• Dr Richard Shepherd: Lessons from 23,000 Postmortems- including Hungerford, Hillsborough and Princess Diana

  Britain’s leading forensic pathologist Dr Richard Shepherd has performed over 23,000 postmortems and given evidence in some of the most high-profile cases of our time, from Hungerford to Hillsborough, from Princess Diana to David Kelly. But his fascination with death began much earlier, when his mother died suddenly from heart disease and he was left with questions no one could answer.In this episode of Full Disclosure, Dr Shepherd tells James O’Brien how that childhood loss set him on the path to forensic medicine, how his father’s emotional openness shaped him, and how a book brought into school by a friend gave him his first glimpse of a profession that would define his life. He reflects on the leap from observing to performing autopsies, the responsibility of telling the truth in court, and the lasting emotional toll of cases that never leave you.Candid, unflinching and deeply human, Dr Shepherd shares how a lifetime spent uncovering the truth about death has shaped the way he lives.Find out more about Dr Richard Shepherd Time of Death tour here

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• Arabella Weir: At nine my mum said, “I can’t bear the sight of you”

  Actor, comedian and bestselling author Arabella Weir grew up in a family that prized intellect and appearances but struggled to offer love. In this episode of Full Disclosure, she tells James O’Brien how an unsettled childhood shaped her fearless streak, her need to perform, and her instinct to turn pain into comedy.From the brutal remarks of her mother to the liberating chaos of Camden School for Girls, Arabella charts the path that took her from rejection at drama schools to finding her voice on The Fast Show and beyond. She reflects on the role of therapy, the challenge of writing, and what it means to live alongside the little girl she once was.Wry, fearless and full of heart, Arabella shares how survival became strength- and why she’s determined to live on her own terms.Find out more about An Evening with The Fast Show here

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• Natalie Haynes: Greek Myths, Medea and the Comedy of Classics

  Natalie Haynes has never been easy to categorise. A stand-up comedian turned broadcaster and best-selling author, she has built a career out of making the ancient world vivid, funny and urgent. In this episode of Full Disclosure, James O’Brien talks with the presenter of Stand Up for the Classics about her unusual path from Birmingham bookshops to the Edinburgh Fringe, and from Radio 4 to re-imagining Medea.They explore the strange alchemy of combining scholarship with humour, the myths that refuse to let her go, and why Jason may be one of antiquity’s least heroic heroes. Natalie reflects on the teachers and family who first filled her life with books, the risks of carving out a career that no one else was doing, and the joy of turning classical stories into something alive for modern audiences.Clever, warm and very funny, Natalie shows how ancient tragedy and modern comedy can illuminate each other- and why she still feels most at home with the ghosts of Greece.Find out more about Natalie Haynes book and tour No Friend to This House here

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• From The Vault: Brian Cox

  From a childhood in Dundee marked by loss, poverty and resilience, to becoming one of the most respected actors of his generation, Brian Cox’s life and career have been defined by an unrelenting pursuit of truth on and off stage. In this in-depth conversation with James O’Brien, the Emmy and Golden Globe winner reflects on the death of his father at eight years old, the formative influence of his mother’s struggles with mental health, and the teachers who first spotted his talent.Cox charts his journey from the Dundee Repertory Theatre to the Royal Shakespeare Company, the West End and Hollywood, revisiting the defining roles that shaped his craft- from portraying Hannibal Lecter before Anthony Hopkins to his acclaimed turn as Logan Roy in Succession. He speaks candidly about the compromises and convictions that have steered his career, the cultural and political forces that have shaped his worldview, and his ongoing belief in the power of storytelling to confront injustice.Thoughtful, uncompromising and rich with anecdote, this episode offers a compelling portrait of an actor whose commanding presence is matched by his fierce intellect and refusal to play by the rules.

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