The DeSci Podcast

• The Solution to Science's BIGGEST PROBLEM | Kevin Noessler

  What if we could reinvent intellectual property for science? In this episode of Molecule’s DeSci Podcast, Kevin Noessler - Product Head at Molecule - joins us to talk about the next frontier of DeSci Science: Proof of Invention.Kevin unpacks how Molecule is building infrastructure for decentralized IP creation, ownership, and attribution. This episode zooms in on how DeSci tools can validate and tokenize early-stage scientific ideas—before patents or papers.We cover:• Kevin’s background and his role in shaping Molecule’s product roadmap• What “Proof of Invention” really means—and how it works onchain• Rethinking IP and scientific reputation through cryptographic primitives• UX challenges when designing for biotech DAOs• The difference between building SaaS vs protocols in DeSci• How open-source values translate into credible scientific infrastructureWhether you’re an innovator, researcher, or builder—this episode is a roadmap for the future of intellectual property in science.⏱ Timestamps:00:00 - Intro01:10 - Kevin’s background & journey to Molecule05:00 - What does a Product Head do in a decentralized org?09:20 - SaaS vs Protocol: Rethinking product building13:00 - Contributors, not customers: the shift in stakeholder models17:15 - UX challenges for onchain science tools21:40 - What makes a product work in DeSci?26:00 - Building with researchers in mind30:30 - Kevin’s long-term vision for Molecule35:00 - Advice for builders entering DeSci39:20 - Outro ________🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]______Special thanks to: - Kevin Noessler: https://x.com/Noesslek- Ella McCarthy-Page: https://x.com/EMcCarthyPage______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• IP, DAOs & Cultural Ownership: Jesse Hudson Reveals the FUTURE of DeSci

  What if the future of science and biotech was built on legal frameworks that empower communities, not corporations?In Episode 44 of the Molecule Podcast, we sit down with Jesse Hudson — lawyer, anthropologist, and Chief Legal Architect at Molecule. Jesse is a pioneer in building legal infrastructure for decentralized science (DeSci), DAOs, and intellectual property (IP) tokenization.This episode dives deep into:- The failure of the current global IP system- IP as cultural infrastructure- IP tokenization and why it matters for DAOs- Licensing, enforcement, and the problem of patent trolls- How indigenous IP and cultural property are being reclaimed through blockchain- New models for governance, dispute resolution, and community-owned IPJesse’s unique experience working with Amazonian tribes, biotech DAOs, and legal DAOs brings one of the most profound and ethical perspectives to the DeSci conversation.Timestamps:0:00 – Intro: Why IP matters2:13 – Meet Jesse Hudson: Legal architect & anthropologist5:05 – From anthropology to biotech DAOs7:44 – IP in the digital age: Why it’s grown 70x11:02 – How IP impacts individuals: NIL rights & personal brands15:10 – IP basics: Trademark, copyright, patents20:05 – Patent trolls & the licensing problem27:01 – Is the IP system serving the public?30:10 – Tesla & IP strategy: When to share vs protect33:42 – DAOs as IP holders: SideDAO & decentralized licensing36:10 – IP tokens & collective governance38:18 – Indigenous cultural IP: Working with the Shipibo tribe44:20 – NFT royalties & licensing for indigenous art48:52 – IP ethics: Alternative models beyond Western frameworks53:22 – DAO-based dispute resolution & legal evolution59:50 – Closing thoughts: Cultural values driving IP systems🔗 Learn more at https://molecule.xyz

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• Graham Pechenik Reveals The FUTURE of Psychedelic Patents | The DeSci Podcast

  The psychedelic industry is booming, but a major battle is unfolding: Who will control the future of these powerful medicines? Will open science prevail, or will corporations dominate through patents? In this episode, we sit down with Graham Pechenik, a leading expert in psychedelic patent law, to unravel the complexities of intellectual property in the space.Graham Pechenik is the founder of Calyx Law, a law firm specializing in psychedelic and cannabis patents. With a background in neuroscience and law, he provides deep insights into the legal landscape shaping the future of psychedelic medicine.Topics Discussed:• The role of patents in psychedelic research• Controversies around corporate control and monopolization• How open-source models could challenge big pharma• What legal battles mean for researchers, startups, and patients• The future of psychedelic accessibilityTune in to get expert insights from one of the leading voices in psychedelic IP law.______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: Ella McCarthy-Page - https://x.com/EMcCarthyPageGraham Pechenik - https://x.com/calyxlaw______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• The Future of Biotech: AI, Patents, and the Innovation Battle

  Biotech is at a crossroads—AI, intellectual property, and startups are reshaping the future. But who really controls the breakthroughs? In this episode, Sara Holland, an IP advisor, explores how patents impact biotech, the challenges startups face against big pharma, and whether AI will change everything.What You’ll Learn in This Episode:- The hidden barriers to biotech innovation- How AI is transforming drug discovery and synthetic biology- The role of patents in protecting—or stifling—progress- Why decentralized science (DeSci) could be the key to the future______Special Thanks To:Ella McCarthy-Page : https://x.com/EMcCarthyPageSara HollandChris BrynesMark Nichols______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.com/invite/moleculedao______Molecule - The future of medicine belongs to everyone

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• Decentralized Science vs. Rare Diseases: A Game-Changer? | Ethan Perlstein

  Welcome to another episode of the DeSci Podcast. Today, we are discussing a critical issue that affects over 30 million people in the United States—Rare Diseases. Despite being more prevalent than cancer and HIV combined, rare diseases remain underfunded, overlooked by Big Pharma, and trapped in a broken system.Our Guest: This episode features Ethan Perlstein, founder of CureTopia, an initiative using Decentralized Science (DeSci) and blockchain to revolutionize rare disease research. Why does the current system fail millions of patients, and how can decentralized models change that?What You’ll Learn in This Episode:-The reality of rare diseases and why the term "rare" is misleading-How patients and parents are taking control of scientific research-Why Big Pharma does not prioritize rare diseases and the funding challenges involved-How DeSci and blockchain can disrupt traditional biotech and accelerate drug development-The vision behind CureTopia and how it is reshaping research for rare disease treatmentsResources Mentioned:CureTopia: https://curetopia.xyzDeSci Podcast: https://www.molecule.xyzFeel free to navigate through any of the topics discussed in the podcast using the timestamps below.___⭐ Timestamps:0:00 - Introduction: The Rare Disease Crisis2:14 - Why Rare Diseases Are More Common Than People Think5:13 - Challenges in Rare Disease Advocacy9:25 - How Parents Become Scientific Experts in Their Child’s Disease13:50 - Why Big Pharma Ignores Rare Diseases17:16 - The Role of Decentralized Science (DeSci) in Drug Development22:41 - The Funding Challenges in Rare Disease Research27:34 - How Blockchain and Smart Contracts Can Help Rare Disease Research33:04 - The Power of Community in Rare Disease Advocacy38:26 - What Is CureTopia and How Does It Work?43:57 - The Future of Rare Disease Research and Biotech Innovation49:14 - Ethan Perlstein’s Vision for CureTopia54:10 - Closing Thoughts and Where to Learn More______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to:Jillian Casalini: https://x.com/JillianCasaliniEthan Perlstein: https://x.com/eperlste____Let's connect: Website: https://bit.ly/3d6nh2CX: https://twitter.com/Molecule_daoDiscord: https://discord.com/invite/moleculedaoMolecule - The future of medicine belongs to everyone!

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