The DeSci Podcast

• The Future of Cancer Therapy: Modular, Safe & Open!

  What if your immune cells came with a smart upgrade?In this episode of the DeSci Podcast, we speak with Dr. Henry Erdlei, medical doctor, cancer researcher, and founder of GoCart, a new cell therapy platform building safer, modular CAR-T therapies through decentralized science.Henry breaks down:* How CAR-T cell therapies work* The real-world risks of immune overactivation* Why cancer is hard to distinguish from healthy tissue* The problem with existing logic gates in cell therapies* His own innovation: an external AND-gate adapter system* Why DeSci and IP-NFTs are the right path for early-stage therapeutics🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]:00 – Intro: What is CAR-T therapy?2:00 – Henry’s background & journey into cancer research4:20 – What T-cells do and why they fail in cancer7:30 – CAR-T vs chemotherapy: cost, complexity, and potential11:00 – Which cancers are eligible for CAR-T treatment?13:10 – Risks: cytokine storms, immune cascades, suicide switches17:30 – Emily Whitehead: the first CAR-T success story20:30 – Current limitations of approved CAR-Ts (CD19, BCMA)23:00 – Introducing GoCart and their “AND gate” design26:00 – Why tumor targeting needs precision logic29:00 – Modular CAR-Ts and the future of personalized medicine32:00 – Why GoCart is building in public with Molecule34:30 – Can DeSci unlock truly customizable cell therapies?37:00 – From research to startup: bridging the valley of death40:00 – How to follow GoCart and get involved______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• The Hidden Quantum World Inside Your Body!

  What if you were told that your body is secretly responding to Wi-Fi signals you can't even feel?In episode 49 of the Molecule Podcast we meet Dr. Geoff Anders (Founder, Leverage) and Dr. Clarice D. Aiello (Quantum Engineer), to explore the cutting-edge field where quantum physics meets biology, revealing how the smallest particles in the universe might be controlling the largest processes in life itself. Whether you're a scientist, technologist, or simply curious about the quantum world around us, this deep dive into quantum biology will change how you think about life, technology, and the future of medicine.        • Quantum biology explained in simple terms• Weak magnetic field effects on cellular processes• The radical pair mechanism and quantum sensing in nature• Space exploration and magnetic field implications• DeSci (Decentralized Science) and crypto funding for research• The future of quantum-controlled medicine• Open science and radical transparency in researchTake a leap into the never ending world of science and imagination with this podcast.Timestamps:00:00:02 - Introduction to Quantum Biology00:02:31 - Quantum Physics in Everyday Life00:04:34 - Understanding the Micro to Macro Connection00:08:11 - Weak Magnetic Fields and Cellular Response00:10:31 - Space Exploration and Magnetic Fields00:14:10 - Mars Colonization Challenges00:15:10 - Future Applications00:16:57 - Personal Backgrounds00:18:36 - From Quantum Sensors to Biology00:20:16 - The DeSci Connection00:27:07 - Real-World Applications Vision00:31:09 - Multiple Flavors of Quantum Biology00:35:45 - Music and Plant Growth00:43:19 - The Consciousness Question00:54:06 - Radical Open Science00:55:15 - How to Get Involved00:56:39 - Final Thoughts🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: ______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• If Einstein Was Born Today, He Would Have Chosen DeSci!

  What if science wasn’t locked in labs or universities?In episode 47 of the Molecule Podcast, we meet Juan Keymer, Assistant Professor, Shenzhen X-Institute who enlightens us on the existing academic pipeline and how it can be made more flexible with the advancement in AI, DeSci (Decentralized Science), Blockchain Innovation, Open Credentials and more.• Reimagining the future of Science with DeSci.• This is a deep, thoughtful, and radically hopeful conversation about the future of learning, research, and planetary collaboration.• Indulge in a world of Science with Juan Keymer and Ella McCarthy-Page (SciComms Lead at Molecule) away from textbooks and traditional academic systems.In this fascinating episode, we dive deep into reimagining the infrastructure of science away from elite institutions and toward decentralized, gamified systems that anyone can engage in.Timestamps00:00:00 – Introduction: A New Vision for Science00:03:15 – The Problem with Academia & Closed Scientific Systems00:10:47 – Open Degrees & Scope for Open Credentials 00:15:20 – The New Scientific Interface00:20:34 – Biotic Games: How Living Systems Become Game Mechanics00:28:45 – Open Hardware and Decentralized Labs00:35:06 – Rewiring Academia: Parallel Programming & Self-Credentialing00:37:00 – Metaverse & Blockchain-Powered Ecosystems00:41:00 – Fun First, Research Second00:43:00 – Final Reflections: The Power of Play in Scientific Discovery🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• $2.2B in Research Grants Frozen: Can DeSci Save Research?

  Over $2.2 billion in NIH research grants are frozen. Labs are going dark. What happens now?In Episode 46 of the Molecule Podcast, we speak with Aaron Weaver, Chief Commercial Officer at Molecule, about the ongoing NIH funding crisis, its global impact, and how decentralized science (DeSci) is becoming a critical alternative.Aaron brings a unique vantage point from the intersection of venture capital, biotech, and public science funding. This episode unpacks:• The real story behind the NIH funding freeze• Why the budget cuts on indirect costs are threatening university research• What happens when academia loses funding momentum• How DeSci offers new models for sustainability and collaboration• How to get involved — even if you’re not a researcherIf you care about the future of scientific discovery, this episode is essential.Timestamps- 0:00 – Intro: The NIH funding crisis1:30 – What’s actually frozen? Why $2.2B is stalled2:50 – Meet Aaron Weaver: CCO of Molecule & DeSci advocate5:00 – Why indirect costs are at the center of the issue9:00 – How operational freezes threaten lab survival11:30 – The fragility of foundational science13:45 – NIH’s critical role in FDA-approved drugs17:00 – Academic research vs. commercialization pipelines20:15 – Who’s affected most? Young researchers & labs23:00 – Global ripple effects & talent displacement27:00 – Why traditional VC can’t fill the gap30:10 – DeSci as a market structure for resilient funding32:45 – Are universities ready for DeSci?35:20 – Connecting scientists with global communities37:10 – Science as public purpose and personal mission40:00 – How you can get involved in the DeSci movement🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: Aaron Weaver : https://x.com/RealAaronWeaverJillian Casalini : https://x.com/JillianCasalini______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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• How SpineDAO Is Redefining DeSci - From Back Pain to Blockchain

  What if your next spine surgery was coordinated by a DAO?In Episode 48 of the Molecule Podcast, we’re joined by Vincent Challier, spine surgeon and co-founder of SpineDAO, and Virginie Lafage, medical strategist and Core Team member, to explore how decentralized science can transform a field as specialized and critical—as spinal health.SpineDAO is building one of the first focused medical DAOs on the Bio Launchpad. In this episode, we cover:• Why spinal health is overlooked in innovation• The power of patient and clinician-led DAOs• Challenges of onboarding medical professionals into DeSci• Real-world use cases for DAOs in healthcare• Why Solana? Technical decisions behind the DAO’s designWhether you’re into biotech, DAOs, or the future of decentralized medicine, this conversation bridges science, surgery, and Web3 in a way you’ve never heard before.⏱️ Timestamps 0:00 – Intro: Meet Vincent & Virginie from SpineDAO2:10 – How they met and started the DAO5:18 – From spine surgery to decentralization: Why this field?8:50 – Building a community around spine health12:42 – Why spinal innovation is long overdue17:20 – Challenges patients face in current medical systems24:10 – How DAOs can unlock patient-centric research29:45 – Engaging surgeons and clinicians in DeSci36:30 – Building accessibility into Web3 onboarding40:00 – Why SpineDAO chose Solana44:23 – The Bio Launchpad auction and what’s next49:04 – A message to their future community52:10 – The real-world use case for SpineDAO______🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]_________Special thanks to: Vincent Challier : https://x.com/challaireVirginie Lafage : https://x.com/VirginieLafageElla McCarthy-Page :https://x.com/EMcCarthyPage______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

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