IHC Talk: Small Cell Lung Carcinomas with Dr. Natasha Rekhtman
The Chromogen Siblings return to talk about small cell lung carcinomas. Drs. Mike Arnold (@MArnold_PedPath), Andrew Bellizzi (@IHC_guy), and Sanam Loghavi (@sanamloghavi) speak with Dr. Natasha Rekhtman (@natasharekhtman) of Memorial Sloan Kettering Cancer Center. Hear about how Pathologists use IHC to identify subsets of small cell lung carcinomas, and the cycle of how molecular data informs IHC approaches and histologic classifications in Pathology.
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Featured articles:Â
SCLC Subtypes Defined by ASCL1, NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization
https://www.jto.org/article/S1556-0864(20)30755-3/fulltext
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POU2F3 in SCLC: Clinicopathologic and Genomic Analysis With a Focus on Its Diagnostic Utility in Neuroendocrine-Low SCLC
https://linkinghub.elsevier.com/retrieve/pii/S1556-0864(22)00299-4
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Featured public domain music:Â Alpha Hydrae, Won't see it comin'
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52:57
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52:57
Beyond the Scope: Genitourinary Pathology with Dr. Sean Williamson
In this segment, Beyond the Scope, we speak to pathologists about their pursuits and interests in and outside of pathology.
On this episode, host Dr. Sara Jiang (@Sara_Jiang) speaks with Dr. Sean Williamson (@Williamson_SR). Dr. Williamson is Professor of Pathology and Vice Chair of Education at the Cleveland Clinic. He is the Editor In Chief of the International Journal of Surgical Pathology, Co-Author of The Atlas of Genitourinary Pathology: A Pattern Based Approach, and author of nearly 200 peer-reviewed publications.
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Hear their conversation about the WHO classification of genitourinary tumors, mentorship and peer-reviewed publications. Also, Dr. Williamson shares his best Disney travel tips!
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Links to papers referenced in the episode:
Nephrogenic adenoma origin: https://pubmed.ncbi.nlm.nih.gov/12200552/
SDH-deficient RCC: https://pubmed.ncbi.nlm.nih.gov/25034258/
RCC staging survey: https://pubmed.ncbi.nlm.nih.gov/29878933/
IJSP website: https://journals.sagepub.com/home/IJS
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Featured public domain music: US Army Blues, BugaBlue
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46:45
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46:45
PathPod's 5th Birthday
In this episode, we celebrate PathPod's 5th Birthday by listening back to the first ever PathPod Quiz Show from April 30, 2020.
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Happy Birthday PathPod!
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57:40
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57:40
IHC Talk: AI in Pathology and IHC with Dr. Matt Cecchini
In this edition of IHC Talk, Dr. Mike Arnold (@MArnold_PedPath), Dr. Andrew Bellizzi (@IHC_guy), and Dr. Sanam Loghavi (@sanamloghavi) delve into the exciting (and sometimes intimidating!) world of Artificial Intelligence and its potential to revolutionize pathology. They're joined by special guest Dr. Matt Cecchini (@Path_Matt), a pathologist with a keen interest in AI.
What you'll discover:
Matt's unorthodox path to Pathology
The role of IHC in conjunction with AI.
The need for rigor and consistency in data
How can the practicing pathologist work with AI to improve?
Get ready for a lively discussion that covers everything from image analysis and mitigating bias to AI agents. The crew dives deep into real-world examples, current tools like ChatGPT, and even the ethical considerations as AI takes on more responsibilities in diagnostic settings. Is AI about to replace pathologists, or can it augment our abilities to deliver better patient care? Listen in and explore the possibilities with this engaging episode!
Thanks to Dr. Cecchini for using Gemini to generate this episode description, and ChatGPT to generate the cover art!
Featured public domain music:Â Alpha Hydrae, Won't see it comin'.
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52:31
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52:31
IHC Talk: Soft Tissue with Dr. David Papke
The Chromogen Siblings are back to talk about soft tissue sarcoma diagnosis and classification. Drs. Mike Arnold (@MArnold_PedPath), Andrew Bellizzi (@IHC_guy), and Sanam Loghavi (@sanamloghavi) speak with Dr. David Papke of Harvard University. Hear about his work and thoughts on identifying new diagnostic entities in soft tissue pathology. We also hear his remembrance of the late Dr. Christopher Fletcher and the influence Dr. Fletcher had on his career and the field of soft tissue pathology.
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Featured public domain music:Â Alpha Hydrae, Won't see it comin'.