What’s next for IBD care: Insights from a surgeon-scientist
The data is clear: inflammatory bowel diseases like ulcerative colitis and Crohn’s are on the rise worldwide. In this episode, we sit down with Dr. Amy Lightner—VP of Clinical Development at Calibr-Skaggs and colorectal surgeon at Scripps Clinic—to explore what drives these diseases, an upcoming phase 2 clinical trial for a new regenerative medicine, and how she balances life between the operating room and the research lab. //Keywords and topics: Inflammatory bowel disease; Crohn’s disease; ulcerative colitis; colon cancer; pouchitis; IBD phase 2 clinical trial; CLF065; colorectal surgery Additional resources:About Amy LightnerLinkedIn - Amy LightnerInstagram - Lightner labFacebook - Lightner labScripps Research Magazine
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23:12
Scientists offer their best career (and life) advice
This year on Science Changing Life, we’ve had some amazing scientists join us to share their work, their stories and what drives them. There’s one question we love to ask our guests: What advice would you give to scientists just starting out? We compiled their refreshingly honest answers into one episode—hear what they had to say.
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8:45
Wired for risk: The science of addiction and mental health
Depression and alcohol dependence are often seen as personal struggles—but decades of study by Scripps Research professor Cindy Ehlers reveal a much bigger picture. In this episode of Science Changing Life, Ehlers breaks down how biology, culture and trauma interact to shape mental health outcomes.Learn how her work is paving the way for more effective interventions, and how new strategies—like culturally grounded prevention programs and digital tools—can reduce harm in high-risk communities.//Ehlers lab: https://www.scripps.edu/ehlers/index.html Scripps Research Magazine: https://magazine.scripps.edu
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Pathogens in the pipeline: How wastewater holds clues to the next pandemic
What if the key to detecting the next pandemic was hidden in our wastewater? By analyzing pathogens found in sewage, scientists can track the spread of infections before they become widespread threats. In this episode of Science Changing Life, project scientist Josh Levy and PhD student Praneeth Gangavarapu explain how analyzing what goes down the drain can offer life-saving insights into the future of public health. Learn more about the role of wastewater surveillance in tracking a range of viruses—including SARS-CoV-2, H5N1 and even seasonal influenza. //Bluesky: https://bsky.app/profile/josh-levy.bsky.social, https://bsky.app/profile/praneethg.bsky.social Andersen lab: https://andersen-lab.com/ Scripps Research Magazine: magazine.scripps.edu/
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Virologist gives update on H5N1, mpox, and preparing for an uncertain future
Roughly two years ago, virology expert and Scripps Research professor Sumit Chanda sat down with Science Changing Life to discuss all things pandemic preparedness and COVID-19. But the world is in a very different place now, with infectious disease threats like H5N1, mpox and Dengue virus on the rise. Chanda joins us once again to share the latest in the virology space, how scientists can be better communicators, and his advice for making sure we’re as prepared for an uncertain future as we can be.
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Chanda lab: chandalab.org/
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Scripps Research Magazine: magazine.scripps.edu/
The award-winning Science Changing Life podcast offers an inside look into how Scripps Research scientists are solving the most pressing mysteries in human health and disease. Join hosts Lauren Fish and Melissa Suran, PhD, as they speak with world-class scientists at the forefronts of immunology, infectious disease, artificial intelligence, personalized medicine, neuroscience and much more.
Science Changing Life gives listeners a glimpse into the people behind the science, their motivations, paths to discovery, and how they’re changing the world.
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