Let's Talk Micro

• 184: Lariocidin

  Discovery of new potential antimicrobial compounds is important as we take many measures to combat antimicrobial resistance (AMR). In this episode Luis is joined by Dr. Manoj Jangra and Dr. Dmitrii Travin to discuss lariocidin: a potential antibiotic. What is the mechanism of action? What are lasso peptides? Tune in to listen about the discovery of this potential antibiotic, organisms it has shown activity against, challenges, and more.    Link to article: https://www.nature.com/articles/s41586-025-08723-7   Questions? Feedback? Send those to [email protected]   Want to support the podcast? Here's how:   Venmo: https://venmo.com/u/letstalkmicro   Buy me a Ko-fi: https://ko-fi.com/letstalkmicro  

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• 183: 101 Topics for Clinical Microbiology Lab Leaders

  There are many challenges in the microbiology laboratory. As a leader, you have to deal with things like validations, verifications, and knowledge of regulations among other things. As a microbiologist in a non-leadership position you need to be familiar with some of these as well. With so much information out there, where do we go? In this episode Luis is joined by Dr. Rebekah Martin, author of the “101 Topics for Clinical Microbiology Laboratory Leaders” book. This book was made in order to bring all of this information to one place. In the episode Dr. Martin discussed the process of writing the book, what type of content it has, and more.  Link to purchase the book:  https://www.wiley.com/en-us/101+Topics+for+Clinical+Microbiology+Laboratory+Leaders%3A+Accreditation%2C+Verification%2C+Quality+Systems%2C+and+More-p-9781683674474   Questions? Feedback? Send those to [email protected]   Want to support the podcast? Here's how:   Venmo: https://venmo.com/u/letstalkmicro   Buy me a Ko-fi: https://ko-fi.com/letstalkmicro  

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• 182: TBT- Next Generation Sequencing

  The field of Microbiology continues to change. Organisms were primarily identified in the clinical laboratory by biochemical testing. Then MALDI-TOF came to the lab and was incorporated into the workflow. Now labs are bringing next-generation sequencing (NGS). What is NGS? How does it work? Have you heard of Nanopore technologies? In this episode Dr. Jose Alexander and Daniel Navas from Advent Health Orlando, join the podcast to talk about NGS. They brought it to their laboratory and discuss the whole process, including the validation, challenges, and more. This episode was originally published on February 9th, 2024 Guest: Dr. Jose Alexander Daniel Navas Questions? Feedback? Send those to [email protected] Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro

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• 181: Microbiology CAP Checklists: Latest Updates

  Is your laboratory accredited by the College of American Pathologists (CAP) ? Are you familiar with their checklists? What are the latest updates to the microbiology checklist? In this episode Luis is joined by Dr. Christi Wojewoda to discuss the latest updates to the microbiology checklist: media quality control and nomenclature.  Why are some media exempt and some non-exempt? Regarding nomenclature, do we need to report the new name or the old name? Tune in to find out.   ASM IQCP template link: https://asm.org/protocols/individualized-quality-control-plan-iqcp   Questions regarding checklists? Contact CAP at [email protected] Questions? Feedback? Send those to [email protected] Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro

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• 180: CLSI M100-Ed35: updates and more

  The latest edition of the CLSI M100 has been published. What are the latest updates? One of them is the deletion of breakpoints for Burkholderia cepacia complex. What are the recommendations for susceptibility testing? Dr. April Bobenchik returns to the podcast to talk to Luis about the latest updates. She also talks about the M45. Will there be an update to the M45? Tune in to find out. Link to CLSI free resources: https://clsi.org/all-free-resources/ Link to webinar: https://clsi.org/standards/products/microbiology/documents/m100/ Questions? Feedback? Send those to [email protected] Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro

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