The Plus SideZ: Cracking the Obesity Code

• Why GLP-1s are So Expensive: i-MAK

  Resources for the Community___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55Find Your US Representatives https://www.usa.gov/elected-officials United States Patent & Trademark Office Website and Email https://www.uspto.gov/[email protected] Websitehttps://www.i-mak.org/i-MAK Briefs & Reports https://www.i-mak.org/resource-type/briefs/______________________________________________________________________Tahir Amin, founder of I-MAK, joins us to break down why GLP-1 meds like Ozempic and Mounjaro stay so pricey. We dig into evergreening, patent thickets, and how pharma companies use legal loopholes to delay generics and extend monopolies.We also explore why some companies spend more on stock buybacks than drug innovation—and what that means for access. If you’ve felt exploited by the system, you’re not alone. But there’s hope. Learn about the policy changes ahead and how you can take action to fight for affordable meds.Tahir Amin bio:Tahir Amin is a founder and CEO of the Initiative for Medicines, Access & Knowledge (I-MAK), a nonprofit organisation working to address the systemic inequities in how medicines are developed and distributed. He has over 30 years of experience in intellectual property (IP) law, during which he has practised with two of the leading IP law firms in the United Kingdom and served as IP Counsel for multinational corporations. His work focuses on changing the structural power dynamics that allow health and economic inequities to persist by challenging and re-shaping IP laws and the related global political economy to better serve the public interest.  He is a former Harvard Medical School Fellow in the Department of Global Health & Social Medicine and has served as legal advisor/consultant to many international groups, including the European Patent Office and World Health Organization, as well as testifying before the U.S. Congress on intellectual property and unsustainable drug prices.Special Guest Co-Host, Amanda Bonello from GLP-1 Collective https://glp1collective.org/ _______________________________Send us Fan Mail!Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

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• Can You Come Off GLP-1? Former FDA Commissioner Explains

  Resources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55______________________________________________________________________Dr. David Kessler, former FDA Commissioner and author of Diet, Drugs, and Dopamine, joins us to break down the science behind food addiction, obesity, and GLP-1 medications like Ozempic and Zepbound.He doesn’t just study this—he lives it. Dr. Kessler has obesity, takes GLP-1s, and knows firsthand what it’s like to battle food noise and weight stigma.In this episode, we discuss:What makes ultra-processed food addictiveHow GLP-1s affect the brain and reduce cravingsWhether some people can stop taking GLP-1sHis personal experience starting, stopping, and restartingWhy weight regain happens and what the body is really fightingHis bold policy ideas to regulate Big Food like Big TobaccoDr. Kessler helped bring HIV drugs to market faster, led Operation Warp Speed, and took on the tobacco industry. Now, he’s focused on the next public health crisis: food addiction and obesity.Subscribe to The Plus SideZ Podcast for more expert conversations on GLP-1s, weight, and wellness.Specialist and Community Guest Dr. David KesslerBIO: David. A. Kessler, MD, served as chief science officer of the WhiteHouse COVID-19 Response Team under President Joe Biden and previouslyserved as commissioner of the US Food and Drug Administration underPresidents George H.W. Bush and Bill Clinton. He is the author of the_New York Times_ bestsellers _The End of Overeating_ and_ Capture_ andtwo other books:_ Fast Carbs, Slow Carbs_ and _A Question of Intent_.Dr. Kessler is a pediatrician and has been the dean of the medicalschools at Yale and the University of California, San Francisco. He is agraduate of Amherst College, the University of Chicago Law School, andHarvard Medical School.Social Media:https://x.com/DavidAKesslerMDLink to Book:https://www.audible.com/pd/B0D5KS9P4D?source_code=ASSORAP0511160006&share_location=pdpSpecial community guest Mike on a Health Mission Social MedSend us Fan Mail! Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

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• GLP-1 Not Working Anymore? Understanding Weight loss Stalls & Plateaus Part 2

  Resources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55______________________________________________________________________If you’ve ever hit a weight loss stall and thought, “What am I doing wrong?”—this one’s for you.In this episode, we sit down with Dr. Lindsay Ogle, a board-certified obesity medicine specialist, to unpack what’s really happening when the scale stops moving, even on a GLP-1. We explore the body’s built-in defenses against weight loss, the role of metabolic disease, and how hormones—especially during perimenopause and menopause—complicate the picture. Dr. Ogle breaks down the science with compassion, helping us understand why stalls happen, how to respond to them, and why it’s not about failure. It’s about biology.Joining us as well is a powerful voice from the community: Mrs. Clark, who began sharing her journey through a nervous breakdown in 2022 on social media and unexpectedly found herself with millions of followers. After years of struggling with her weight, she decided to try tirzepatide—and it changed everything. She opens up about the emotional toll of obesity, what it felt like to stall, and why the journey is about so much more than a number on the scale.We also dig into obesity phenotypes and why GLP-1 medications don’t work the same way for everyone. For those not seeing the results they expected, Dr. Ogle walks us through combination therapies, mindset shifts, and what sustainable care really looks like.This episode is a reality check wrapped in compassion. Whether you’re stalled, stuck, or just trying to make sense of what your body is doing, this conversation is your reminder: you’re not alone—and it’s not your fault.Community Guests Mrs ClarkTik Tok: @mrskariclarkDoctor GuestsDr. Lindsay OgleDr. Lindsay Ogle, MD is a board certified family & obesity medicine physicianwho is passionate about preventative health. Her goal is to help patients stay healthy so they may live longer and fuller lives. She recently started a telehealth clinic called Missouri Metabolic Health where she helps adults all throughout the state of Missouri treat and prevent metabolic conditions (ex: diabetes, fatty liver disease, metabolic syndrome, overweigSend us Fan Mail! Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

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• GLP-1 Not Working Anymore? Understanding Weight loss Stalls & Plateaus Part 1

  Resources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55______________________________________________________________________If you’ve ever hit a weight loss stall and thought, “What am I doing wrong?”—this one’s for you.In this episode, we sit down with Dr. Lindsay Ogle, a board-certified obesity medicine specialist, to unpack what’s really happening when the scale stops moving, even on a GLP-1. We explore the body’s built-in defenses against weight loss, the role of metabolic disease, and how hormones—especially during perimenopause and menopause—complicate the picture. Dr. Ogle breaks down the science with compassion, helping us understand why stalls happen, how to respond to them, and why it’s not about failure. It’s about biology.Joining us as well is a powerful voice from the community: Mrs. Clark, who began sharing her journey through a nervous breakdown in 2022 on social media and unexpectedly found herself with millions of followers. After years of struggling with her weight, she decided to try tirzepatide—and it changed everything. She opens up about the emotional toll of obesity, what it felt like to stall, and why the journey is about so much more than a number on the scale.We also dig into obesity phenotypes and why GLP-1 medications don’t work the same way for everyone. For those not seeing the results they expected, Dr. Ogle walks us through combination therapies, mindset shifts, and what sustainable care really looks like.This episode is a reality check wrapped in compassion. Whether you’re stalled, stuck, or just trying to make sense of what your body is doing, this conversation is your reminder: you’re not alone—and it’s not your fault.Community Guests Mrs ClarkTik Tok: @mrskariclarkDoctor GuestsDr. Lindsay OgleDr. Lindsay Ogle, MD is a board certified family & obesity medicine physicianwho is passionate about preventative health. Her goal is to help patients stay healthy so they may live longer and fuller lives. She recently started a telehealth clinic called Missouri Metabolic Health where she helps adults all throughout the state of Missouri treat and prevent metabolic conditions (ex: diabetes, fatty liver disease, metabolic syndrome, overweighSend us Fan Mail! Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

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• Perimenopause, Menopause, HRT & GLP-1s Explained with Dr. Cathleen Brown Part 2

  Resources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55Start your perimenopause HRT journey with Winona  https://winona.pxf.io/gOLeV0______________________________________________________________________Start your perimenopause HRT journey with Winona  https://winona.pxf.io/gOLeV0 Part 2Let’s talk about the change. Chances are, it’s already happening, and nobody handed you a guidebook.In this episode, we sit down with Dr. Cathleen Brown, Medical Director at Winona, to finally demystify perimenopause and menopause. We’re bringing this conversation to our audience because so many people on a GLP-1 journey are also navigating hormonal shifts. Whether it’s perimenopause, menopause, or just the hormonal chaos of midlife, these changes can impact everything—from weight and sleep to mood and metabolism.We’re here to break it all down.From night sweats and mood swings to insulin resistance and hormone shifts, we cover it all with real talk and science-backed solutions. Dr. Brown walks us through the current landscape of hormone replacement therapy (HRT), including estrogen, progesterone, testosterone, and even Osphena. She also addresses the past fears about HRT—strokes, heart attacks, cancer—and how updated research is changing the conversation around safety, longevity, and quality of life.We also explore the role of GLP-1 medications in the menopause space, especially for those with PCOS, insulin resistance, or other metabolic challenges. Could these meds be part of a modern menopause toolkit? Dr. Brown shares her perspective.And yes, we get personal too. As Winona patients ourselves, we’re sharing what’s worked, what hasn’t, and what questions we had going in—so you don’t have to figure it all out alone.What you’ll hear in this episode:What perimenopause and menopause actually are (and why it matters)Why hormone disruptions are common during the GLP-1 journeyGLP-1s and menopause: emerging research and real-world useHRT today: what’s changed, what’s safer, and what’s workingTestosterone, Osphena, and how to treat painful sexHabiSend us Fan Mail! Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

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