Two Scientists Walk Into a Bar

Is the human heart an evolutionary miracle or a single point of failure? In this episode, host Maria Wilson is joined by Saptarsi Haldar, Senior Vice President, Head of Research Biology, to dive into the central engine of the human body. Together they explore how the heart functions, what happens when it fails, and the evolution of treatment, up to the latest breakthroughs. From the future of cardiac repair and precision medicine to the game-changing role of AI, this episode is a front-row seat to the next frontier of cardiovascular science. Join us to learn about the muscle that powers billions of lives.

Read the full text transcript at www.gene.com/stories/state-of-the-heart

How can artificial intelligence help our scientists find the hidden patterns in cancer's complex biology? In this episode, host Danielle Mandikian is joined by Anwesha Dey, Distinguished Scientist and Executive Director of AI - Oncology and Cancer Biology, to talk about the new reality of the oncology lab. They explore how teaming up with artificial intelligence allows researchers to challenge long-held assumptions, generate bold hypotheses and design novel molecules at speed. Join us to hear how working alongside AI is accelerating the path to new cancer therapies.

Read the full text transcript at www.gene.com/stories/ai-in-oncology

Are we on the cusp of a new era in scientific research? This episode delves into the transformative potential of the "lab of the future." Host Danielle Mandikian and guests Margaret Porter Scott, VP, Biochemical Cellular Pharmacology, and Andy Lash, Head of Engineering, Lab Automation, discuss how AI and automation are set to tackle major bottlenecks in science, from fragmented systems to the physical and time-intensive toll of repetitive lab work. Discover how these advancements will lower the activation energy for groundbreaking research and empower scientists to better tackle some of humanity’s most pressing medical needs.

Read the full text transcript at www.gene.com/stories/lab-of-the-future

Inflammatory bowel disease (IBD) is a debilitating, lifelong condition that changes how people plan their entire lives. In this episode, KT Park, Global Head of Gastroenterology and Hepatology, and Seppi Lin, Head of OMNI Early Clinical Development, explore the complex biology behind IBD. They discuss the role of genetics, the gut microbiome, and an individual’s environment, as well as the exciting future of "immune reset" therapies that could offer hope for people with IBD.

Read the full text transcript at www.gene.com/stories/the-abcs-of-ibd

Breakthroughs in the last decade have transformed how we understand and treat multiple sclerosis (MS), but what will it take to stop the disease in its tracks? Pull up a stool with co-host Maria Wilson and our guest Sherman Jia, Group Medical Director, gRED Translational Medicine, for a discussion on the breakthrough research into B cells that has made a "night and day" difference for people living with the disease. In this episode, they tackle the next frontiers in MS research: from the surprising link between the Epstein-Barr virus and MS, to the ambitious goal of repairing the brain’s myelin, and the potential of “immune reset” therapies, including work in cell therapies, that could offer lasting remission.

Read the full text transcript at www.gene.com/stories/breakthroughs-in-ms