54. William Morris (NuMat) on metal organic frameworks (MOFs)
William Morris of NuMat talks about metal organic frameworks (MOFs) for filtration, separation, and storage of gases, as well as about his journey helping spin out a startup from Northwestern University. Bryce Meredig joins as co-host.OUTLINE(00:00) Introduction(00:53) Career path(05:29) NuMat’s origin(06:10) Metal organic frameworks (MOFs)(10:39) Market opportunity(12:16) Partnership models(14:35) Invention to commercialization(16:48) Partnership with Merck(17:32) Technoeconomics(20:39) Market pull(23:07) Market research and customer discovery process(27:08) Challenges(31:46) Culture and team dynamics(33:48) Vision for NuMat
--------
36:34
--------
36:34
53. Mark Warner (Liberation Bio) on scaling biology
Mark Warner of Liberation Bioindustries speaks about the importance of scaling biology and shifting focus from R&D to manufacturing. Adam Lawrence cohosts.OUTLINE(00:00) Introduction(00:39) Career (02:36) Definition of biomanufacturing(03:46) Comparison with chemical manufacturing (07:14) History and evolution of biomanufacturing (10:15) Current state of biomanufacturing(13:01) Role of government (17:49) R&D vs manufacturing(20:10) Ramifications of only R&D focus (25:40) Financing and technoeconomics(27:27) Workforce development(30:48) Liberation Bioindustries(40:31) Vision of future of US biomanufacturing
--------
45:18
--------
45:18
52. Nádia Parachin (Integra) on industrial biotechnology
Nádia Parachin of Integra discusses industrial biotechnology. Adam Lawrence co-hosts.OUTLINE(00:00) Introduction(00:49) Education and career(02:21) Tech transfer and innovation financing in Brazil vs. US(08:52) Industrial biotechnology - definition and advantages(14:33) Key drivers for industrial biotech(16:21) Platform vs Product business models(20:38) Current state of industry(25:59) Examples of success(28:18) Bottlenecks(30:25) Commercialization strategy (33:15) Lessons learned and advice
--------
35:51
--------
35:51
51. Robert Stoner (Kendall Square Project) on translating academic research into businesses
Robert Stoner of Kendall Square Project and previously of MIT Energy Initiative speaks about licensing as a way to bring academic and scientific research to the market.OUTLINE(00:00) Introduction(00:39) Education and career path(07:58) Financing mechanisms for deeptech ventures (12:45) Role of universities(15:34) Licensing (23:11) Role of government(31:03) Scientists turning entrepreneurs(34:31) Translating science into business(38:36) Energy technologies, demand and supply
--------
47:34
--------
47:34
50. David Heller (C16 Biosciences) on biomanufacturing and palm oil alternatives
David Heller of C16 Biosciences speaks about biomanufacturing technology and products and business strategy. Adam Lawrence co-hosts.
OUTLINE
(00:00) Introduction
(00:32) Career path
(03:13) Origin of C16 Biosciences
(07:12) Palm oil agriculture
(10:06) C16 Bio’s core technology
(11:14) IP strategy
(16:22) Products
(18:50) Competitors
(21:02) Value ecosystem
(24:05) Positioning
(25:32) Criticisms of precision fermentation
(28:56) Technoeconomics and cost drivers
(33:25) Resources and inputs
(35:27) Capital costs
(38:31) Challenges
(41:29) GMO
(42:15) Regulatory landscape
(45:08) Risks
(51:17) Vision
Ireland