Core IM | Internal Medicine Podcast

Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside?
In this high-yield episode, test your clinical reasoning as we tackle:
When eosinophilia becomes dangerous and why it matters
How to distinguish if its from atopy vs. systemic disease
Which medications to stop (and which to watch)
How travel, diet, and exposure history shape your workup
When to suspect malignancy before giving steroids

🔹Transcript and Shownotes: 
02:34 | Why Do We Care About Eosinophilia? (Pearl 1)
10:24 | Atopy and Eosinophilia (Pearl 2)
18:57 | Drugs and Eosinophilia (Pearl 3)
27:29 | ID and Eosinophilia (Pearl 4)
33:54 | Pearl 5: Eosinophilia, Steroids, and Neoplasms (Pearl 5)

Tags: CoreIM, Internal Medicine, Medical Education, Eosinophilia, Hypereosinophilia, Allergy Immunology, Hematology, Pulmonology, Parasitic Infections, Atopy

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Is coffee helping or harming our patients’ hearts?
In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question:
How should clinicians interpret nutrition research, especially when it feels inconsistent or hard to trust?
Listen for a concise, practical framework you can use the next time a patient asks about coffee, diet, or lifestyle.

🔹Sponsor: Oakstone CME
Use the code "CORE325" for 25% off: https://www.coreimpodcast.com/MKSAP 
🔹 Transcript and Show notes
00:00 | Challenges of interpreting nutritional research.
02:22 | Best practices for evaluating studies in nutrition. 
12:35 | Delve into the CRAVE trial as an example of critically appraising nutritional investigations.
26:41 | Applying this to clinical practice for your patients.

Tags: IMCore, Internal Medicine, Medical Education, Epidemiology, Diet and Lifestyle

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Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students, residents, and clinicians who want a clear, usable approach.

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🔹Transcript and Shownotes:
02:15 | Pearl 1: Pathophysiology
08:20 | Pearl 2: Diagnosis
16:35 | Pearl 3: Treatment
20:35 | Pearl 4: Antibiotics
27:39 | Pearl 5: Wound Care

Tags: CoreIM, Internal Medicine, Medical Education, Diabetic Foot Infections, Osteomyelitis, Foot Ulcer, Wound Care

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A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded?
A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI?
A patient arrives in the ED with uremic symptoms and a newly created AV fistula. Can you safely use it, or do you need to place a temporary dialysis catheter?
And the classic inpatient dilemma: your heart failure patient looks better after diuresis, but the creatinine is rising. Is it time to stop, or should you keep going?

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See here for Neph Madness details 
See here for the POCUS region of NephMaddness
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🔹Transcript and Shownotes:

00:52 | What is NephMadness?
02:19 | Detecting post-renal obstruction in a patient who reported normal urination
11:26 | POCUS for discharge or continue diurese
17:25 | Distinguishing COPD from volume overload in a dialysis patient using lung ultrasound
23:55 | Assessing AV fistula maturity at the bedside to potentially avoid placing a temporary dialysis line

Along the way, we discuss practical ways clinicians can use renal, lung, and venous ultrasound to clarify uncertain clinical situations and make faster decisions at the bedside.

If you’ve ever paused on rounds, wondering “what should we do next?” in a patient with kidney disease, this episode explores how POCUS can help answer that question.

Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, AKI Management, POCUS

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Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them.
• Do cholinesterase inhibitors really work?
• What should clinicians know about lecanemab and donanemab before referring patients?
• How much benefit should we expect and for how long?
• When should you deprescribe dementia medications?

🔹Sponsor: Caraway’s cookware set is a favorite for a reason.
For 10% off, go to Carawayhome.com/CoreIM or use code CoreIM at checkout.

🔹Transcript and Shownotes
02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia?
09:41 | Deep Dive 2: Prescribing medications for cognitive decline
29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline
35:46 | Deep Dive 4: Planning for an uncertain future

Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant

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