The Beyond Tomorrow Podcast with Julian Issa

What if the key to aging better is taking care of your body's batteries?
For 20% off all Timeline products, go to timeline.com/beyondtomorrow
Dr. Singh explains why mitochondrial health is becoming a major focus in longevity science. He unpacks the research behind urolithin A, how it supports cellular renewal, and why supplements should never replace the basics.
The conversation covers the habits that matter most, from exercise and sleep to fasting and gut health. They also explore how to separate real science from longevity hype.
Finally, they look ahead to the future of healthy aging, where better diagnostics, AI, and preventive medicine could help us stay healthier for longer, not just live longer.
Dr. Singh is the Chief Medical Officer at Timeline and a physician-scientist specializing in immunology, mitochondrial health, and longevity. His research focuses on translating cutting-edge science into evidence-based interventions that help people age healthier.
What You’ll Learn
Why mitochondrial health matters for longevity

How urolithin A supports healthy aging

The habits that have the strongest evidence

How to spot longevity hype

Where longevity science is headed next

⏱ Timestamps
00:00 Intro
00:14 Why Urolithin A Matters
02:20 The Best Ways to Boost Mitochondria
03:20 Can We Reverse Aging?
06:37 Why Your Immune System Ages First
08:20 Targeting the Hallmarks of Aging
10:53 Fifteen Years, One Mission
12:24 The Search for a Longevity Superfood
15:26 Do You Really Need Supplements?
17:58 Three Ways to Improve Mitochondrial Health
20:02 Creatine + Urolithin A Explained
21:41 What Early Users Reported
24:13 Where Skincare Meets Longevity
25:42 Why Longevity Takes Time
28:15 The Three Pillars of Healthy Aging
30:01 The Shift to Preventive Medicine
31:50 Why Mitochondria Are Going Mainstream
34:35 Mitophagy vs. Autophagy
35:38 How Antibiotics Affect Aging
37:49 Rebuilding Your Gut Microbiome
39:59 Prebiotics vs. Probiotics vs. Postbiotics
42:11 The Most Underrated Longevity Habit
43:30 The Gut-Brain Connection
45:04 Melatonin and Mitochondrial Health
45:58 The Biggest Longevity Myth
46:35 Why Metabolic Health Matters
48:19 When GLP-1 Drugs Make Sense
49:32 The Hidden Downsides of GLP-1s
51:12 What Centenarians Can Teach Us
52:48 Mitochondrial Health in 2031
54:17 If Tomorrow Is Your Last Day...

Connect with Dr. Singh
Website: https://www.timeline.com/ 
Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 
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Could AGI arrive within the next three to four years and super-intelligence follow almost immediately?

Emad Mostaque, founder of Intelligent Internet, explains why he believes the first stage of the singularity has already begun, why recursive self-improvement could accelerate AI from AGI to ASI in as little as a day, and why the convergence of AI and quantum computing could transform the world faster than most people expect.

In this clip, Emad reveals why leading AI experts believe AGI is rapidly approaching, how today’s models are already outperforming top programmers, and why many jobs could become economically irrelevant within the next 1,000 days.

Watch the full episode here: https://open.spotify.com/episode/6oqWQWDYX90uQUmZ5hcB4Q?si=9bf0fbe2159246c5

What happens when intelligence stops being uniquely human?

I’m really excited to announce our new sponsor, AgelessRx, a leading longevity telehealth platform that connects you with licensed clinicians for evidence-based treatments.  Get 20% off your first order at agelessrx.com using code BEYONDTOMORROW

AI may be changing more than how we work. Joscha Bach argues that it could fundamentally reshape how we think, relate to others, and understand ourselves. The future may be difficult to predict because technology is changing the very models we use to understand it.

The conversation moves from AI agents and universal basic intelligence to consciousness and agency. Bach explores whether machines could become more than tools, and whether AI might eventually extend human minds and biology onto new substrates.

But the biggest question may not be whether AI becomes conscious. It is whether humanity can build and govern these systems wisely. Bach argues that AI could make society more capable, but only if we develop better incentives, stronger long-term thinking, and a positive vision for the future.

Joscha Bach is a computer scientist, philosopher, and researcher focused on artificial intelligence, cognition, and machine consciousness. He founded the California Institute for Machine Consciousness to explore how minds can self-organize through controlled experiments.

What You’ll Learn
Why the AI revolution may be bigger than previous technological shifts

How AI could become an extension of human intelligence

Why agency may matter more than machine consciousness

How the brain creates a simulated model of reality

Whether consciousness could emerge on different substrates

Why AI alignment is also a problem of human alignment

How AI could help humanity become smarter and more coherent

⏱ Timestamps
00:00 Intro
00:09 What Happens When AI Escapes?
02:08 Can AI Become Your Second Mind?
05:30 The Rise of Universal Basic Intelligence
07:42 Will AI Make Everyone Smarter?
10:52 Doomers vs. AI Companies
16:15 Why AI Progress Surprised Everyone
17:27 Why Nobody Believed in AI
21:00 Could AI Become Smarter Than Humans?
27:23 Your Brain Is Running a Simulation
29:01 Does AI Really Need Consciousness?
32:48 AI Could Help Build a Better World
36:24 AI Is the Interactive Internet
38:22 Is Humanity Running Out of Time?
41:03 What Is AI’s Greatest Risk?
43:46 We Are the AI
45:30 Why China Could Lead AI
48:17 Why Elon Builds What Others Won’t
51:17 Who Controls How Smart AI Gets?
55:47 Can AI Threaten Our Freedom?
57:13 Why Does Everyone Fear AI Doom?
01:00:33 The AI Panopticon Is Coming
01:04:48 AI Is Already Surpassing Experts
01:06:14 Can AI Actually Destroy the World?
01:08:21 Why AI Experts Disagree
01:09:09 Is Death Real in a Simulation?
01:09:36 Do Minds Really Have Identity?
01:11:55 Can Claude Actually Feel?
01:14:06 Is the Universe a Computer?
01:15:45 What’s the Best Advice You’ve Received?
01:17:58 Is Free Will Just Psychological?
01:19:06 If Tomorrow Was Your Last Day...

Connect with Joscha
Website: http://bach.ai/ 
Substack: https://joscha.substack.com/ 
LinkedIn: https://www.linkedin.com/in/joschabach/ 
X: https://x.com/Plinz  

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 

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Can we really live to 180 or even beyond?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

Dave Asprey believes the future of longevity is arriving much faster than most people realize. He explains why personalized medicine, gene therapies, AI, and biohacking could fundamentally change how we age, and why simply extending healthspan isn't an ambitious enough goal.

From peptides and GLP-1 drugs to creatine, sleep, brain optimization, and nutrition, Dave challenges conventional wisdom on nearly every aspect of health. He argues that the future of medicine won't be based on population averages, but on personalized interventions tailored to each individual's biology.

He also shares why biohacking became a global movement, why embracing calculated risk is essential for progress, and why the biggest breakthrough in longevity may come from giving people greater control over their own health decisions.

Dave Asprey is an entrepreneur, author, and the founder of the biohacking movement. He is the creator of Danger Coffee, a multiple-time bestselling author, and one of the world's leading voices on longevity, cognitive performance, and human optimization.

What You’ll Learn
Why Living to 180 Is Just the Beginning

How Personalized Medicine Is Changing Longevity

The Future of Gene Therapy, Peptides & Biohacking

GLP-1, Creatine & The Next Generation of Health

Why Biohacking Is Becoming a Global Movement

The Biggest Longevity Mistakes Most People Make

⏱ Timestamps
00:00 Intro
00:04 Can You Really Live to 180?
01:46 How Epigenetics Prevents Aging
04:08 Why Taking Risks Extends Life
05:06 The Truth About N=1 Health
07:54 Are Side Effects Overblown?
09:39 Why Biohacking Won
13:26 Biohacking Was Never About Supplements
15:34 Track What You Hack
17:28 Are Peptides Actually Dangerous?
20:10 The Two Minds Controlling Your Body
23:16 Why Governments Should Fund Peptide Research
24:48 Could GLP-1 Slow Aging?
28:09 Why Dave Quit Veganism
30:11 Is Too Much Olive Oil Harmful?
31:42 Is Beef Tallow Actually Healthy?
33:09 The Truth About Creatine
35:01 How Much Creatine Do You Really Need?
36:07 Do You Really Need 8 Hours of Sleep?
39:53 The Best Cognitive Enhancers
41:02 Psychedelics and Human Consciousness
43:50 Can Your Organs Regrow?
47:23 The Future of Stem Cell Therapy
52:45 Is NAD Worth Taking?
54:19 Lessons From Divorce and Co-Parenting
56:17 The Secret to Lasting Happiness
57:48 Choose Your Partner Carefully
59:03 Dave's Long-Term Biohacking Plan
01:00:05 Is Living Forever a Curse?
01:01:37 Does Reincarnation Exist?
01:02:44 Are We Living in a Simulation?
01:05:36 What Psychedelics Really Taught Me
01:06:59 Low-Dose Nicotine for Longevity?
01:08:27 Why You Should Track Yourself
01:10:09 Why Some People Love Pain
01:11:31 The Science of Orgasm and Longevity
01:16:25 The Biggest Longevity Scam
01:17:30 Five Levels of Life Extension
01:21:26 Why Therapy Scares People
01:23:28 The Most Powerful Longevity Habit
01:24:45 Have Humans Stopped Aging?
01:25:54 The Next Longevity Breakthrough
01:28:24 Why Death Gives Life Meaning
01:29:45 The Best Advice Dave Ever Received
01:31:59 If Tomorrow is Your Last Day...

Connect with Dave
Website: https://daveasprey.com/ 
Facebook: https://web.facebook.com/Daveaspreyofficial 
Instagram: https://www.instagram.com/dave.asprey 
TikTok: https://www.tiktok.com/@daveaspreyofficial 
X: https://x.com/daveasprey 
YouTube: https://www.youtube.com/c/DaveAspreyBPR
LinkedIn: https://www.linkedin.com/in/asprey  

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com

Could AI redefine what it means to be human or put humanity itself at risk?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

As AI races toward AGI, Emad Mostaque explores the biggest questions facing humanity. He explains why the next few years could determine whether AI becomes humanity's greatest tool or its greatest threat.

From the future of work to AI governance, personhood, quantum computing, and longevity, Emad paints a future where intelligence becomes abundant. But he warns that without the right incentives and safeguards, that future could quickly turn dystopian.

He also shares why he believes AGI is much closer than most people expect and why building AI that serves humanity is the most important challenge ahead.

Emad Mostaque is the founder of Intelligent Internet, which is combating corporate tech monopolies and now pioneering decentralized, sovereign, and verifiable AI architectures. He is an Oxford-educated mathematician, former quantitative hedge fund manager and tech entrepreneur who founded Stability AI and launched Stable Diffusion.

What You’ll Learn
Why Emad Thinks AGI Is Only a Few Years Away

The Choice Between AI Abundance and Dystopia

Why AI Should Never Be Granted Personhood

How Decentralized AI Could Protect Humanity

Why AI Could Solve Most Diseases Within a Decade

How Quantum Computing Will Supercharge AI

What the Singularity Means for Humanity

⏱ Timestamps
00:00 Intro
00:11 What It Really Means to Be Human
01:31 Why Systems Always Overoptimize
03:28 Intelligence at the Edge
05:44 Will AI Require a License?
07:34 The AI Duopoly Problem
08:35 Why AI Can't Become a Person
11:23 Can AI Replicate Itself?
15:57 AI Doomers vs Optimists
20:15 How Do We Save Humanity?
21:35 What Should We Teach AI?
25:08 Can Good AI Stop Bad AI?
27:47 AGI vs ASI Explained
30:08 Who Wins the AGI Race?
31:31 Small Changes, Massive Impact
32:52 The Last Human Discoveries
35:01 Can AI Become Conscious?
39:10 What AI Does Better Than Humans
43:09 Why Quantum Changes Everything
44:44 Where to Invest in the AI Era
46:52 Life After ASI
48:50 Will AI Judge Humanity?
51:09 The Inevitable AI Future
53:50 Universal High Income
56:07 Owning AI Instead of Jobs
57:48 The Rise of a Service Economy
01:00:09 Why Human Purpose Will Change
01:01:45 Why Family Matters More Than Ever
01:04:02 Finding Meaning in an AI World
01:06:01 The Value of Human Intelligence
01:07:52 Why Curiosity Still Wins
01:09:49 Be Creative, Embrace Technology
01:12:11 Why Are We Born?
01:13:00 Emad's Best Advice
01:19:16 AI and the End of Work
01:21:48 Ending Human Suffering
01:26:26 A World Run by AI
01:27:49 If Tomorrow is Your Last Day...

Connect with Emad
Website: https://ii.inc/ 
LinkedIn: https://uk.linkedin.com/in/emad-mostaque-9840ba274 
X: https://x.com/EMostaque 

Connect with Julian
Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  
Instagram: https://www.instagram.com/juliankissa/  
LinkedIn: https://uk.linkedin.com/in/julian-issa  
Website: www.beyondtomorrowpodcast.com 
Email: bookings@beyondtomorrowpodcast.com 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.