The Longevity & Lifestyle Podcast

Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie

This episode is brought to you by:

BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com

Get 20% off with code CLAUDIA20.

What happens when the brain temporarily lets go of the identity, memories, and personal story that make you feel like “you”?

In this episode of the Longevity & Lifestyle Podcast, Claudia speaks with Tommaso Barba, psychedelic researcher at Imperial College London, whose work explores consciousness, ego dissolution, 5-MeO-DMT, mental health, relationships, and the nature of the self.

Tommaso explains why psychedelics are returning to mainstream science after decades of prohibition, how psilocybin, LSD, DMT, 5-MeO-DMT, MDMA, ketamine, and ibogaine differ, and why pharmaceutical companies are now investing heavily in psychedelic medicine.

They examine the limitations of conventional psychiatric treatment, including the idea that depression is simply a chemical imbalance, and explore why psychedelic experiences may reach psychological, emotional, social, and spiritual dimensions that existing medications often do not address.

Tommaso also shares his personal high-dose psilocybin experience, describing the dissolution of his identity, a sense of boundless awareness, and the challenge of returning to ordinary life after experiencing profound presence and connection.

This conversation does not present psychedelics as casual shortcuts. It explores the importance of preparation, set and setting, skilled facilitation, integration, contraindications, and the cultural structures needed to support these powerful experiences safely.

IN THIS EPISODE
• Why psychedelics are entering mainstream medicine
• How psychedelic research was halted for decades
• Psilocybin, LSD, DMT, 5-MeO-DMT, MDMA, ketamine, and ibogaine
• Why depression is more complex than a chemical imbalance
• How set, setting, and integration shape outcomes
• Why unsupported psychedelic use can become destabilizing
• How 5-MeO-DMT is being used to study consciousness
• What ego dissolution can feel like
• Neuroplasticity, psychological flexibility, and mental health
• Who may not be suitable for psychedelic treatment
• Psychedelics, intimacy, sexuality, and relationships
• The future of psychedelic medicine and psychiatry

TIMESTAMPS
00:00 Introduction
02:28 Psychedelics enter the pharmaceutical mainstream
05:27 Why psychedelic research was banned
10:12 The major psychedelic compounds explained
12:46 Why modern psychiatry needs new approaches
15:34 Set, setting, and altered states
18:56 Why support and integration matter
20:23 Tommaso’s path into psychedelic research
22:41 Psychedelics, religion, and The Immortality Key
24:46 Using 5-MeO-DMT to study consciousness
26:37 What happens when the self dissolves?
27:49 Depression, neuroplasticity, and 5-MeO-DMT
30:47 Psychedelics for depression, PTSD, and addiction
32:39 Why psychedelics are not for everyone
34:02 Tommaso’s experience of ego dissolution
39:12 Psychedelics, intimacy, and relationships
42:35 The future of psychedelic medicine
44:16 Final message: stay curious

#TommasoBarba #Psychedelics #PsychedelicScience #Psilocybin #5MeODMT #MentalHealth #Consciousness #Neuroplasticity

Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie

This episode is brought to you by:

BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com

Get 20% off with code CLAUDIA20.

What if the constant pressure to improve yourself is reinforcing the anxiety you are trying to escape?

In this episode of the Longevity & Lifestyle Podcast, Claudia welcomes Jamie Clements, breathwork facilitator, speaker, educator, and founder of The Breath Space.

Jamie shares how anxiety, depression, and panic attacks led him away from a high-performing career in finance and technology and toward a deeper exploration of breath, nervous system health, consciousness, and human potential.

He explains how breathing influences the autonomic nervous system, why dysfunctional breathing can reinforce stress and anxiety, and how simple changes in breathing speed, depth, and rhythm can shift how we feel and perform.

They also explore carbon dioxide tolerance, nasal breathing, breath holding, sleep apnea, altered states of consciousness, trauma-aware breathwork, and the risks of practicing deeper techniques without the right preparation or facilitator.

This conversation also challenges the modern obsession with optimization. Jamie explains why high performers often find rest uncomfortable, how achievement can become tied to self-worth, and why slowing down may be one of the most powerful ways to improve creativity, energy, and performance.

IN THIS EPISODE

• How anxiety and panic attacks led Jamie to breathwork
• Why the breath directly influences the nervous system
• Signs that you may be breathing dysfunctionally
• Why carbon dioxide is essential for oxygen delivery
• Nasal breathing, mouth breathing, and cognitive health
• Box breathing, extended exhales, and the physiological sigh
• How breathwork can create altered states of consciousness
• Trauma, emotional release, and breathwork safety
• Why high performers struggle to rest
• The link between achievement and self-worth
• How slowing down can improve productivity

TIMESTAMPS

00:00 Introduction
03:44 Jamie’s experience with anxiety and panic attacks
06:15 Losing his job and discovering a different path
09:26 Why we underestimate the power of breathing
12:15 Ancient breathwork traditions
15:43 How breathing controls the nervous system
18:06 Using breath to change your internal state
19:33 CO2 tolerance and stress resilience
24:58 Signs you may be breathing incorrectly
27:39 The three levels of breathwork
31:13 Trauma release and breathwork safety
33:54 What an altered-state breathwork session feels like
38:29 Why high performers struggle to slow down
41:43 Purpose, ambition, and self-worth
43:24 Creating work-life harmony
48:57 The Breath Space
50:33 Why you do not need fixing

ABOUT JAMIE CLEMENTS

Jamie Clements is a breathwork facilitator, speaker, educator, and founder of The Breath Space. His work brings together functional breathing, neuroscience, psychology, trauma-aware practice, ancient wisdom, and nervous system regulation.

#JamieClements #Breathwork #NervousSystem #Anxiety #StressRelief #MentalHealth #Consciousness #TraumaHealing #Burnout #LongevityPodcast

Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie

This episode is brought to you by:

BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com

This week’s picks: BioRetina, ShredMAX, BioGutPro, and BioRestore.

Get 20% off with code CLAUDIA20.

What if the peptides and supplements you are taking contain far less than the label claims?

In this episode of the Longevity & Lifestyle Podcast, Claudia welcomes back Jay Campbell, bestselling author, peptide educator, and co-founder of BioLongevity Labs and BioLongevity Supplements.
Jay reveals why he believes much of the peptide and supplement market is filled with counterfeit, underdosed, or poorly tested products.

He explains how consumers can investigate batch numbers, certificates of analysis, ingredient dosages, and third-party testing before trusting a product.

They also explore the rapidly changing regulatory landscape around peptides and GLP-1 medications, why many people experience avoidable side effects, and why peptides should be treated as tools rather than shortcuts.

Jay shares the foundations that should come first, including resistance training, adequate protein, quality sleep, metabolic health, and hormonal balance. He also reveals the three supplements he personally considers most noticeable for energy, gut health, and cognitive performance.

IN THIS EPISODE
• Why peptide quality and testing matter
• How counterfeit and underdosed products enter the market
• What batch numbers and certificates of analysis can reveal
• Why proprietary blends should raise questions
• The biggest mistakes people make with GLP-1 medications
• Why peptides are not magic bullets
• How to assess supplement labels and active dosages
• When supplements should be taken fasted or with food
• Jay’s top products for energy, gut health, and focus
• Why education matters more than hype

TIMESTAMPS

00:00 Introduction
02:26 Why Jay created BioLongevity Supplements
04:13 Peptide regulation and the changing market
11:02 Retatrutide, access, and pharmaceutical control
13:34 What peptides are and how they work
15:31 The history of peptide and bioregulator research
23:06 The future of retatrutide regulation
27:41 Fake and underdosed peptide products
29:08 How to verify peptide quality
32:27 Why many people use GLP-1s incorrectly
34:07 Creating stronger peptide testing standards
38:55 Why peptides are tools, not shortcuts
43:43 Why the supplement industry is broken
51:26 How to read a supplement label
54:01 Active ingredients and proprietary blends
58:15 How oral supplements are absorbed
59:55 Jay Campbell’s top three supplements
01:02:08 Jay’s final message

JAY’S TOP THREE SUPPLEMENTS

Shred Max

BioGut Pro

BioMind

Explore BioLongevity Supplements and receive 20% off with code
CLAUDIA20:
https://biolongevitysupplements.com/shop

#JayCampbell #Peptides #Supplements #GLP1 #BioLongevity #HealthOptimization #GutHealth #BrainHealth #Mitochondria #Longevity

Ready to unlock your brain’s superpower? Download my free 5-Minute Brain Blueprint to boost mental clarity, sharpen focus, and support lifelong cognitive vitality → https://longevity-and-lifestyle.com/BRAIN

This episode is brought to you by:

BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com

Get 20% off with code CLAUDIA20.

What if cognitive decline is not as inevitable as we have been told?
In this episode of the Longevity & Lifestyle Podcast, I welcome back Dr. Dale Bredesen, internationally recognized neurologist, bestselling author, and pioneer in the prevention and reversal of cognitive decline.

Dr. Bredesen shares the findings from his latest randomized controlled trial, in which 90% of participants receiving a precision medicine protocol improved. We explore why Alzheimer’s may begin decades before symptoms appear, the biomarkers that can help identify risk earlier, and the lifestyle and medical factors that may influence cognitive health.

We also discuss the role of sleep, insulin resistance, inflammation, toxins, ketones, peptides, stem cells, GLP-1 medications, psychedelics, and neuroplasticity.

This conversation offers an important message: the earlier we understand what is driving cognitive decline, the greater the opportunity to act.

In this episode, you’ll learn:
• Why Alzheimer’s may begin decades before symptoms
• What Dr. Bredesen’s latest trial revealed
• The stages from prevention to dementia
• Blood biomarkers linked to early decline
• Insulin resistance, ketones, and brain energy
• Sleep apnea and long-term brain health
• Why there is no single cure

TIMESTAMPS
00:00 Introduction
03:37 The Alzheimer’s trial where 90% improved
06:35 What drives cognitive decline
12:01 Why Alzheimer’s is no longer viewed as hopeless
16:08 The four stages of cognitive decline
18:22 Blood tests that may reveal risk earlier
22:22 The key drivers of Alzheimer’s
23:36 The seven foundations of brain health
25:53 Sleep targets for cognitive longevity
28:27 GLP-1s and Alzheimer’s risk
31:35 Peptides for brain health
35:59 Stem cells, exosomes, and regenerative medicine
39:32 Is there hope at every stage?
40:45 Inside the randomized clinical trial
46:18 Psychedelics and neuroplasticity
52:31 Dr. Bredesen’s final message

CONNECT WITH DR. DALE BREDESEN
Website: https://www.drbredesen.com
Free cognitive assessment: https://www.mycqtest.com
Brain biomarker testing: https://www.getabrainscan.com

CONNECT WITH CLAUDIA
Website: https://longevity-and-lifestyle.com
Instagram: https://www.instagram.com/longevityandlifestyle
YouTube: https://www.youtube.com/@LongevityandLifestyle

#DaleBredesen #Alzheimers #BrainHealth #CognitiveDecline #DementiaPrevention #Longevity #PrecisionMedicine #Neuroplasticity

Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie

This episode is brought to you by:

BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com

This week’s picks: BioRetina, ShredMAX, BioGutPro, and BioRestore.

Get 20% off with code CLAUDIA20.

What if the real key to longevity is not just preventing damage - but restoring the body’s ability to repair itself?

In this episode, I sit down with Dr. Ian White, a leading expert in regenerative medicine, stem cell biology, tissue regeneration, and longevity science. We explore how amniotic fluid, Muse cells, and regenerative signaling may help support healing, reduce inflammation, and change the future of longevity medicine.

We also break down what regenerative medicine actually is, how it differs from the way most people talk about stem cells, what matters most for safety, and how this field could reshape the way we think about aging and recovery.

In this conversation, we cover:
00:00 - The accidental discovery that changed regenerative science
00:40 - Could the answer to longevity begin before birth?
02:23 - Dr. Ian White’s path into regenerative medicine
05:13 - Why some animals regrow tissue and humans do not
07:26 - What changes in the body’s repair systems with age
09:29 - Why amniotic fluid is so scientifically interesting
12:55 - What regenerative medicine really means
15:05 - Longevity, healing, and the biology of repair
16:30 - Stem cells vs regenerative medicine
21:05 - Regulation, safety, and responsible clinical use
24:13 - Tissue repair and real-world applications
28:37 - Brain health and regenerative medicine
31:39 - Rejuvenation and the future of anti-aging medicine
39:05 - Muse cells and why they matter
43:40 - Who may benefit most from these therapies
46:37 - How to approach regenerative medicine responsibly
50:23 - Space aging research and the future of longevity science
54:25 - Final thoughts on healing, aging, and what comes next

If you enjoyed this episode, subscribe and share it with someone serious about living longer, healthier, and better.

#Longevity #RegenerativeMedicine #StemCells #HealthyAging #Biohacking #TissueRepair #AntiAging #HealthOptimization