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The Longevity & Lifestyle Podcast

Claudia von Boeselager
The Longevity & Lifestyle Podcast
Latest episode

268 episodes

  • The Longevity & Lifestyle Podcast

    #268 Dr. Edith Shiro — The Unexpected Gift of Trauma: Healing, Resilience & Post-Traumatic Growth

    28/10/2026 | 49 mins.
    Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie

    Can trauma become a source of strength, purpose, and growth?
    In this episode of The Longevity & Lifestyle Podcast, Claudia speaks with Dr. Edith Shiro, licensed clinical psychologist, trauma specialist, co-founder of the Trauma and Resilience Center, and author of The Unexpected Gift of Trauma.
    Dr. Shiro has spent decades studying trauma, PTSD, resilience, and post-traumatic growth. Her work is also shaped by her family history as the granddaughter of Holocaust survivors and Syrian refugees, and by supporting people through 9/11, the Surfside building collapse, war, migration, and other collective traumas.
    Together, they explore why trauma is not only about what happens to us, but how it can reshape our beliefs, relationships, nervous system, and sense of self.
    Dr. Shiro explains why healing begins with radical acceptance, why trauma can live in the body, and why being heard, validated, and connected to others can be such an important part of recovery.
    They also explore post-traumatic growth and how pain can eventually become a source of purpose, compassion, resilience, and service to others.
    IN THIS EPISODE
    • What trauma really is
    • Big T vs small T trauma
    • Intergenerational and collective trauma
    • Why trauma can live in the body
    • How unresolved trauma affects relationships
    • Radical acceptance and emotional healing
    • Turning pain into purpose
    • Post-traumatic growth
    • Gratitude and nervous-system regulation
    • Psychedelics and PTSD
    • Why human connection matters for longevity
    TIMESTAMPS
    00:00 Introduction
    02:03 How trauma became Dr. Shiro’s life’s work
    03:58 Why some people grow after trauma
    06:12 Why trauma lives in the body
    08:42 Why trauma is relational
    12:35 Radical acceptance and healing
    14:53 Why we avoid painful emotions
    17:06 What actually counts as trauma?
    19:57 Big T, small T & intergenerational trauma
    21:33 How the body carries unresolved trauma
    25:04 How unresolved trauma shapes our reactions
    26:32 What is post-traumatic growth?
    29:10 Turning pain into purpose
    29:33 How your wound can become your superpower
    31:00 Claudia shares her childhood trauma
    34:02 Reframing childhood beliefs
    38:19 The power of gratitude
    41:32 Psychedelics and trauma healing
    44:33 Dr. Shiro’s book and work
    46:21 Mental health as a daily practice
    ABOUT DR. EDITH SHIRO
    Dr. Edith Shiro is a licensed clinical psychologist specializing in trauma, PTSD, resilience, and post-traumatic growth. She is the author of The Unexpected Gift of Trauma: The Path to Post-Traumatic Growth.
    #EdithShiro #TraumaHealing #PostTraumaticGrowth #MentalHealth #Resilience #PTSD #Longevity
  • The Longevity & Lifestyle Podcast

    #267 Sander Brus — Sugar, Dopamine, Cravings & the Future of Metabolic Health

    21/10/2026 | 47 mins.
    Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook → https://longevity-and-lifestyle.com/freebie
    This episode is brought to you by:
    Axolt, a daily brain drink with 46 carefully selected ingredients, no caffeine or stimulants, and formulated with input from neurologists and brain health researchers: https://axoltbrain.com/claudia
    Get 20% off through the link above
    Why is sugar so hard to resist, even when you know it is not helping your health?
    Claudia speaks with Sander Brus, scientist, entrepreneur, and founder of NoSu Health, about the biology behind cravings and how to change your relationship with sugar.
    After COVID temporarily took away his sense of taste, Sander stopped reaching for Coca-Cola, changed his eating habits, and lost 15 kilograms. This sparked his exploration of taste receptors, dopamine, and food reward.
    They discuss how ultra-processed foods keep us coming back, why willpower alone often fails, and how glucose swings, GLP-1 medications, and satiety influence appetite.
    Sander also explains NoSu Health and Gymnema sylvestre, the “sugar destroyer,” which can temporarily reduce sweet taste. Plus, discover how at-home diagnostics and AI-powered retinal imaging could support earlier detection of health risks.
    IN THIS EPISODE
    • Sugar cravings, dopamine, and the “bliss point”
    • Blood sugar, insulin sensitivity, and GLP-1s
    • Gymnema sylvestre and sweet taste receptors
    • Practical ways to reduce sugar
    • At-home diagnostics and AI retinal scans
    • Prevention, behavior change, and enjoying life
    TIMESTAMPS
    00:00 Introduction
    01:29 Surfing, dopamine, and big-wave risk
    04:47 Claudia’s father’s stroke recovery
    09:45 How losing taste changed Sander’s relationship with food
    10:30 The “bliss point” and engineered food reward
    12:55 How appearance and texture change how much we eat
    14:22 Why sugar is so hard to resist
    15:00 Dopamine and the brain’s reward pathway
    15:55 Big Tobacco and Big Food
    17:00 Why willpower is not enough
    19:14 GLP-1s and addictive behavior
    20:25 Why ultra-processed food is so difficult to resist
    22:29 Why sugary breakfasts can trigger more cravings
    23:19 The glucose rollercoaster
    25:28 How quitting sugar changed Sander’s body
    26:26 The story behind NoSu Health
    27:00 Blocking sweet taste receptors
    28:49 Reducing glucose spikes and crashes
    29:32 Gymnema sylvestre and metabolic health
    31:08 Where to start if you want to reduce sugar
    31:56 How taste buds can reset
    32:39 Different ways to use NoSu
    35:55 Rewiring the reward response to sugar
    37:20 Is sugar really as addictive as cocaine?
    38:35 The science behind Gymnema sylvestre
    40:00 Sugar hiding under different names
    40:30 NoSu’s ongoing research
    42:17 Can NoSu complement GLP-1 medications?
    43:43 Sander’s other health-tech companies
    44:19 The future of at-home diagnostics
    47:14 Using the retina to assess cardiovascular health
    48:42 Retina scans vs CT calcium scoring
    50:38 Why early detection matters
    53:08 AI, health technology, and behavior change
    55:45 Where to follow Sander
    56:31 Sander’s final longevity advice
    ABOUT SANDER BRUS
    Sander Brus is a Dutch scientist and entrepreneur working across metabolic health, diagnostics, sustainability, and AI. He founded NoSu Health and AUCAS Diagnostics and works with IRO on AI-powered retinal imaging for cardiovascular risk assessment.
    #SanderBrus #SugarCravings #MetabolicHealth #Dopamine #UltraProcessedFood #BloodSugar #Longevity #HealthyAging
  • The Longevity & Lifestyle Podcast

    #266 Gazal Vakili — Meet Your Future Self: Identity, Daily Habits, Visualization & AI

    14/10/2026 | 51 mins.
    Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie
    This episode is brought to you by:
    BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com
    Get 20% off with code CLAUDIA20.
    Axolt, a daily brain drink with 46 carefully selected ingredients, no caffeine or stimulants, and formulated with input from neurologists and brain health researchers: https://axoltbrain.com/claudia
    Get 20% off through the link above
    What if your future self stopped feeling like a stranger and became someone you could talk to, learn from, and feel responsible for?
    Claudia speaks with Gazal Vakili, founder and CEO of Future Self, an AI-powered personal transformation platform that helps people connect with who they want to become.
    With more than 15 years of experience across clinical research, biotech, digital health, virtual reality, cognitive science, and AI-enabled health technologies, Gazal explores how our beliefs and identity influence today's choices.
    Discover how AI voice cloning, personalized meditations, visualization, and daily micro-actions can help bring your future identity into the present. Together, Claudia and Gazal explore purpose, intuition, self-worth, and learning to listen to yourself.
    IN THIS EPISODE
    • Imposter syndrome, identity, and the power of belief
    • Silent meditation, intuition, and self-awareness
    • Why we treat our future selves like strangers
    • The psychology of future-self continuity
    • Creating an emotionally meaningful future vision
    • AI voice cloning and future-self conversations
    • Personalized meditations and daily micro-actions
    • Why worthiness cannot come from achievement
    TIMESTAMPS
    00:00 Introduction
    04:33 Gazal’s journey into Future Self
    05:27 Imposter syndrome
    06:00 The placebo effect and belief
    07:38 Identity and expectations
    08:24 Childhood and self-belief
    09:17 Reprogramming identity
    11:34 The Future Self mission
    12:36 Voice cloning and inner wisdom
    14:21 Silent meditation
    15:28 Sitting with your thoughts
    17:27 Intuition vs the monkey mind
    18:08 Observing your thoughts
    18:58 Journaling for answers
    21:08 Your future self as a stranger
    23:38 Future-self continuity
    24:56 Connecting with your future identity
    26:50 Why identity is not fixed
    27:24 How beliefs filter reality
    29:16 Creating a bold future vision
    30:24 Making your future feel real
    31:00 Talking to your future self
    32:50 Daily guidance and micro-actions
    34:05 Multi-sensory visualization
    35:31 Meditations in your own voice
    36:29 Weekly future-self check-ins
    38:03 Gazal’s transformation
    39:08 An emotional future-self encounter
    40:38 Becoming an entrepreneur
    41:45 Gazal’s daily practice
    44:09 Questioning your identity
    45:17 Listening to yourself
    45:56 What’s next for Future Self
    46:58 Gazal’s final message
    LEARN MORE ABOUT FUTURE SELF
    Website: https://www.future-self.ai/
    Join the waitlist for updates on beta access and future availability.
    #GazalVakili #FutureSelf #AI #Identity #Mindset #Visualization #HumanPotential #PersonalGrowth #LongevityPodcast
  • The Longevity & Lifestyle Podcast

    #265 Sean Hoess — Eudēmonia: Purpose, Community, Longevity & the Science of Living Well

    09/10/2026 | 49 mins.
    Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook → https://longevity-and-lifestyle.com/freebie
    Join Claudia at Eudēmonia in West Palm Beach this November! Get 10% off eligible Standard and Enhanced badges with code LONGEVITYANDLIFESTYLE → https://eudemonia.net/longevityandlifestyle
    What’s the point of living to 100 if you’re not truly enjoying your life?
    In this special episode of The Longevity & Lifestyle Podcast, Claudia welcomes Sean Hoess, Founder and CEO of Eudēmonia, to explore why longevity is about more than living longer.
    From corporate law to co-founding Wanderlust and creating Eudēmonia, Sean shares his journey and the importance of purpose, community, fulfillment, and evidence-based wellness.
    They discuss the evolution of wellness, the power of human connection, navigating health information, self-experimentation, and what makes Eudēmonia a unique gathering for the longevity community.
    IN THIS EPISODE
    • Sean’s journey from corporate law to Wanderlust and Eudēmonia
    • Why purpose and fulfillment are essential to longevity
    • The evolution of evidence-based wellness
    • How community and connection influence well-being
    • Why failure and experimentation support growth
    • Navigating health information and scientific integrity
    • Peptides, self-experimentation, and safety
    • What makes Eudēmonia different and what’s new this November
    TIMESTAMPS
    00:00 Introduction
    01:13 Sean’s journey into entrepreneurship
    05:24 Building Wanderlust and lessons learned
    11:40 The inspiration behind Eudēmonia
    13:15 Living well versus living longer
    15:13 The evolution of wellness
    17:48 Bridging wellness communities
    20:55 Encouraging respectful debate
    22:42 Why purpose matters for longevity
    25:58 Finding purpose through experimentation
    30:55 What makes Eudēmonia different
    33:22 Scientific integrity and commercial influence
    38:13 Peptides and self-experimentation
    44:01 What’s new at Eudēmonia
    46:15 Sean’s final message on purpose
    ABOUT SEAN HOESS
    Sean Hoess is the Founder and CEO of Eudēmonia and co-founder of Wanderlust. His work brings together longevity science, fitness, mindfulness, and community to help people make informed health decisions and live more fulfilling lives.
    COME JOIN US AT EUDĒMONIA
    Join Claudia in West Palm Beach this November and enjoy 10% off eligible Standard and Enhanced badges with code LONGEVITYANDLIFESTYLE.
    https://eudemonia.net/longevityandlifestyle
    #SeanHoess #Eudemonia #Longevity #Wellness #Purpose #Biohacking #HealthyAging #LongevityPodcast
  • The Longevity & Lifestyle Podcast

    #264 Martin Valovsky – Your Brain Needs More Than Neurons: Glial Cells & Everyday Brain Health

    07/10/2026 | 28 mins.
    Ready to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook → https://longevity-and-lifestyle.com/freebie
    This episode is brought to you by:
    BioLongevity Labs, science-led supplements supporting mitochondrial function, gut resilience, recovery, and eye health, with transparent ingredients and third-party testing: https://BioLongevitySupplements.com
    Get 20% off with code CLAUDIA20.
    Axolt, a daily brain drink with 46 carefully selected ingredients, no caffeine or stimulants, formulated with input from neurologists and brain health researchers: https://axoltbrain.com/claudia
    Get 20% off automatically through the link above. No code needed.
    What if brain health depends on the entire infrastructure that keeps neurons alive, fueled, and protected?
    Claudia speaks with Martin Valovsky, co-founder of Axolt Brain, about the overlooked systems supporting long-term brain health, from glial cells and astrocytes to blood flow, the blood-brain barrier, the glymphatic system, and mitochondria.
    They explore how brain damage can accumulate silently, how APOE4 influences risk, and why daily habits matter before symptoms appear.
    Martin shares his experience with double-copy APOE4, why he stopped drinking alcohol, his concerns about sugar, and why he prioritizes movement. They also discuss Axolt’s formulation, polyphenols, bioavailability, and ingredient safety.
    IN THIS EPISODE
    • Glial cells, astrocytes, and the brain’s support systems
    • The blood-brain barrier and glymphatic clearance
    • Sleep, mitochondria, and brain energy
    • APOE4 and Martin’s personal journey
    • Movement, alcohol, sugar, and daily habits
    • Polyphenols, bioavailability, and Axolt’s formulation
    • Supplement safety and when to consult your doctor
    TIMESTAMPS
    00:00 Introduction
    03:54 Why brain health matters
    04:29 Brain health as an infrastructure problem
    05:30 Blood-brain barrier and brain protection
    06:30 The glymphatic system and brain cleaning
    07:49 Why glial cells matter
    08:55 Astrocytes: the brain’s “IT system”
    10:00 Oligodendrocytes and brain signaling
    11:37 Mitochondria and brain energy
    12:13 How much control do we have over brain aging?
    12:36 APOE4 and Martin’s personal motivation
    14:26 Axolt Brain partner message
    16:08 The fundamentals of brain longevity
    16:23 Why Martin stopped drinking alcohol
    17:00 Why he considers sugar a major culprit
    17:30 Why movement comes first
    18:30 Polyphenols and brain health
    19:47 Building the Axolt formula
    20:08 Three years of formulation work
    21:00 Safety and ingredient selection
    22:00 Bioavailability and the blood-brain barrier
    23:30 Spearmint, memory, and brain nutrition
    24:18 What users report
    25:27 Who should speak to their doctor
    25:50 Peptides and brain health
    27:11 Martin’s final message
    ABOUT MARTIN VALOVSKY
    Martin Valovsky is the co-founder of Axolt Brain, a daily brain nutrition company focused on long-term cognitive performance and brain health.
    After more than a decade in the high-pressure defense industry, Martin and his co-founder experienced burnout, brain fog, and poor sleep. This led them to explore the brain’s nutritional needs and develop Axolt with neurologists, researchers, and scientific advisors.
    #MartinValovsky #AxoltBrain #BrainHealth #Longevity #CognitiveHealth #APOE4 #GlymphaticSystem #HealthyAging #LongevityPodcast
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About The Longevity & Lifestyle Podcast
Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!
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