The Glossy Beauty Podcast

What is PDRN?

You've probably seen the four letters on serum bottles, sheet masks and even lip balms — or heard them on TikTok. PDRN stands for polydeoxyribonucleotide and typically refers to a DNA fragment that's often, but not always, derived from salmon sperm and most commonly found in K-Beauty. Of course, on social media, PDRN has an obvious shock value to it, which has led to an onslaught of posts in which lines like, "I just got salmon sperm injected into my face," provide perfect hooks to start videos.

In this week's episode of the Glossy Beauty Podcast, co-host Sara Spruch-Feiner explores what PDRN is, what it purports to do for the skin, how it got so popular and how it is expanding beyond Korean beauty.

To explore the topic, Spruch-Feiner speaks with New York City-based dermatologist Dr. David Kim; the former editor-in-chief of Allure magazine and fractional CMO for K-Beauty distributor Landing International, Michelle Lee; and the founder of Rodial, Maria Hatzistefanis.

L’Oréal Paris is betting on “The Devil Wears Prada 2” through an official partnership that spans TV ads, OOH advertising, social campaigns, consumer eventing and product placement in the film.

L’Oréal officially announced the partnership in March through a commercial that debuted during the Oscars, which drew more than 17 million viewers this year. “It was a huge, huge success and [created] huge buzz,” Branik said. “We also dropped it on social [media] that night, and we had more than 7 billion impressions in one night.”

The commercial starred L’Oréal Paris spokespeople Kendall Jenner and Simone Ashley, set in the movie’s fictional “Runway” magazine offices. Similar commercials were released in the subsequent weeks starring L’Oréal spokesperson Isabella Rossellini and actress Pauline Chalamet, who joined the franchise for the sequel alongside Ashley.

“It’s the first time we’re doing something so big,” Branik said. “We have done product integrations before, but this is a whole new level for us.”

Branik sat down with podcast host Lexy Lebsack to walk through all of the details of the campaign, ways its success may lead to similar investments for L’Oréal Groupe and best practices for navigating product placement.

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Indie Lee launched her namesake beauty brand — a pioneer of the "clean" beauty movement — in 2010. Now owned by parent company American Exchange, the brand is embarking on a new chapter: a diffusion line, Indie Lee Botanicals, which launched at Whole Foods in February. The range launched with a tight edit including a cleanser, toning mist, serum and moisturizer, each priced $20-$25.

On this week's episode of The Glossy Beauty Podcast, Lee joins co-host Sara Spruch-Feiner to explore why now was the right time to launch a lower-priced line, how she approached maintaining efficacy while cutting costs, and how this diffusion brand will grow and shape her core collection's future.

The conversation also dives into how shifting consumer behavior, whether driven by economic pressure or interest in ingredient safety, is reshaping how and where people shop for beauty products.

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Michael Malinsky’s 6-year-old brand Wonderskin could have easily become a one-hit wonder. 

Wonderskin launched in 2020 with a peel-off lip stain that immediately went viral on TikTok for its metallic blue formula and social media-friendly reveal. Since launch, the brand has sold more than 6 million units of the $22 Wonder Blading Lip Stain Peel-Off Mask, according to Malinsky. 

“The unique visual ‘wow factor’ helped us tremendously in capturing attention, but just standing out is a small part [of success],” Malinsky said. “Delivering curiosity, entertainment and ultimately the desire to try a product is what we spent the first two years of the business really honing in on.” 

In fact, Wonderskin’s viral success took years to build. “Our virality curve wasn't instant and up into the right; it was a slow-building momentum while we figured out the right messaging, the right visuals, the right branding, the right communications, the right packaging, the right pricing,” he said. “Only when we were very, very confident in the complete package were we more comfortable in activating the bigger partnerships and shouting a little bit more loudly about our product.” 

As early adopters of TikTok Shop and live selling, Wonderskin leveraged seller tools to grow an online community and saw a 328% increase in return on ad spend, plus a 182% increase in click-through rate, according to a TikTok case study on the brand. 

“The digital entrepreneurs’ anxiety is always there, because whenever something is working well in digital, there's always the concept of the half-life, because at some point, it will be less efficient. At some point, it will be less viral,” Malinsky said.

But what happened next could be considered the more novel part of Wonderskin’s rise: The brand successfully launched into several more categories, including eye and complexion; took on $50 million in funding led by Insight Partners; and launched into traditional retail with Sephora. 

This growth is partially fueled by Malinsky’s data-first approach to performance marketing, including a test-and-learn philosophy to new product launches. "We are confident and comfortable enough to move away from things that don't work," he said.

Wonderskin’s sales revenue grew by 300% in 2023 and 2024, and in 2025, the brand did more than $125 million in revenue, according to Malinksy. Today, Wonderskin sells DTC and through Amazon and TikTok Shop, plus Sephora, Boots, Nordstrom and Revolve. 

Malinsky joined the Glossy Beauty Podcast to discuss the challenges in turning a viral product into a full-fledged beauty brand, including learnings along the way and advice for fueling the fire behind a viral product.

As the beauty industry moves past the direct-to-consumer boom of the 2010s, some of its most influential brands are being forced to redefine what success looks like. One of the most closely watched is Glossier, which recently appointed a new CEO, Colin Walsh, who joined from Ouai. 

On this week’s episode of the Glossy Beauty Podcast, co-host Sara Spruch-Feiner is joined by senior beauty reporter Emily Jensen to discuss the staple millennial brand — which famously helped pioneer the modern "clean girl" aesthetic — and what its next chapter may hold. 

In recent months, the company has undergone several changes. Since Walsh’s appointment, they've included layoffs affecting roughly a third of its workforce, a pullback on physical retail, and a renewed focus on hero products and fragrance, a category now driving significant growth.

Headlines about the brand have often forecasted inevitable doom, but this episode explores Glossier’s current moment beyond a foregone conclusion, examining what it takes for a beauty brand to achieve longevity in an increasingly crowded market, the balance between newness and attention paid to hero products, and the challenge of maintaining relevance across generations.