PodcastsBusinessThe Startup Ideas Podcast

The Startup Ideas Podcast

Greg Isenberg
The Startup Ideas Podcast
Latest episode

342 episodes

  • The Startup Ideas Podcast

    Andrew Wilkinson: AI Agents run my business and life

    14/05/2026 | 47 mins.
    If you want more workflows and tactics to build a business with AI, check out this free workshop: https://www.ideabrowser.com/workshop

    I sit down with Andrew Wilkinson and we go deep on how he's restructured his work, his health, and his family office around AI agents. Andrew walks me through Deep Personality (an app he vibe-coded after running psychological screens on himself and his girlfriend), the autonomous SaaS business he runs through agent harnesses like Harbor, and the vector-database setup that lets him query Tiny and his personal holding company like an oracle. We cover where software is headed, why he's pouring capital into TSMC and data center stocks, and the daily AI workflows he's built around health, email triage, and a personalized morning podcast. Listeners walk away with concrete prompting tactics, agent architectures, and a frank read on where the moats are moving.

    Timestamps:

    00:00 – Intro

    01:50 – The OpenClaw and Claude Code Unlock

    04:53 – Demo: Deep Personality App

    10:38 – Harbor: An Agent Harness For Real Companies

    12:30 – Autonomous Companies: Hype Vs. Reality

    17:30 – Credibility As The Missing Layer For Vibe-Coded Products

    20:14 – Centralizing Data Pipelines

    21:35 – Vector Databases

    23:22 – Transitioning Companies to Agentic Companies

    25:22 – Where Andrew Would Build Today

    27:10 – The New Interface

    28:21 – Why build now

    30:59 – Replacing Adapar: A Networth Wealth Platform

    33:07 – Services As The New Software

    35:24 – G-Brain Explained and Andrew’s OpenClaws

    45:09 – Closing Thoughts

    Key Points

    Andrew runs a SaaS business called Deep Personality almost entirely through agents, generating roughly $20K of revenue while debugging eats half his time.

    Harbor (github.com/geekforbrains/Harbor) gives agents a GUI-style harness — dev, marketing, and support agents that can autonomously merge PRs and adjust ad budgets across PostHog, Meta, and Reddit.

    Andrew's family office swapped headcount for a $40K/month Claude bill; his CFO, who had zero coding background, vibe-coded a replacement for Adapar (priced at $50K–$100K/year) in about two weeks.

    Vector databases trained on Tiny and Andrew's holding company let him query 132 minority investments, P&Ls, and headcount data conversationally.

    For builders today, Andrew suggests aiming for a $1M–$2M product, then parking gains in TSMC and data center exposure given how fast software moats are eroding.

    His best prompting tip: ask the model to interview you with multiple-choice questions before generating any output.

    The #1 tool to find startup ideas/trends - https://www.ideabrowser.com

    LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/

    The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/

    FIND ME ON SOCIAL

    X/Twitter: https://twitter.com/gregisenberg

    Instagram: https://instagram.com/gregisenberg/

    LinkedIn: https://www.linkedin.com/in/gisenberg/

    FIND ANDREW ON SOCIAL

    X/Twitter: https://x.com/awilkinson

    Deep Personality: https://deeppersonality.app

    Tiny: https://www.tiny.com
  • The Startup Ideas Podcast

    The $1M+ Solo AI Agent Business (Full Course)

    12/05/2026 | 47 mins.
    Nick agreed to personally set up your Orgo in a 15 min call: https://startup-ideas-pod.link/orgo_ai

    I sit down with Nick from Orgo to break down exactly how to run a one-person AI agent business that can realistically clear a few million dollars a year. Nick walks through the offer, the verticals worth chasing, the full software stack, and the live setup of an agent that manages other agents. We focus on tactics over theory, with specific tools, pricing, and the playbook for landing customers as a solopreneur. By the end, anyone with solid AI fluency will have a clear path from offer design to fulfillment.

    Timestamps

    00:00 – Intro

    02:54 – Designing the AI Agent Business Offer

    06:38– Selling an AI Employee, Not an Agent

    07:26 – Industries to Target (and Two to Avoid)

    14:54 – Content Is Overpowered and How to Get Customers

    17:51 – The Customer-Facing Tool Stack

    20:49 – Building Agents Stack

    25:51 – Model Picks: GPT 5.5, GLM 5.1, Kimmy, Opus 4.7

    27:08 – Nick’s Stack

    28:14 – Why Obsidian Is the Second Brain Layer

    30:22 – Live Walkthrough: Spinning Up a Cloud Computer in Orgo

    33:53 – Cloud Computers vs. Mac Minis

    38:37 – Building Agents and Structuring Workspaces for Customers

    43:56 – Watchdogs, Observability, and Reliability

    45:28 – Closing Thoughts on the Solopreneur Era

    Key Points

    Sell unlimited agents, unlimited usage, and unlimited support to remove friction; most customers actually use one to three agents.

    Avoid healthcare and finance to start; focus on legacy verticals like marketing, law, insurance, manufacturing, wholesale, and real estate.

    OpenClaw agents go for around 5K a month; Hermes agents can go for 10K a month.

    The full stack: Granola, Trello, Loom, Superhuman, Asana, Codex, Hermes, Orgo, Composio, Agent Mail, and Obsidian.

    GPT 5.5 is the recommended default model for tool calling; GLM 5.1 and Kimmy work for lighter tasks; Opus 4.7 fits long-horizon coding.

    Use agents to set up other agents — pair Cloud Code or Codex with MCPs like Perplexity, Context7, and X MCP for live docs.

    The #1 tool to find startup ideas/trends - https://www.ideabrowser.com

    LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/

    The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/

    FIND ME ON SOCIAL

    X/Twitter: https://twitter.com/gregisenberg

    Instagram: https://instagram.com/gregisenberg/

    LinkedIn: https://www.linkedin.com/in/gisenberg/

    FIND NICK ON SOCIAL

    Youtube: https://www.youtube.com/@nickvasiles

    Instagram: https://www.instagram.com/nickvasilescu/

    Personal Website: https://www.nickvasilescu.com/
  • The Startup Ideas Podcast

    7 tiny AI agent ideas I built with Genspark Claw

    12/05/2026 | 29 mins.
    Get started building your tiny AI Agent business with Genspark Claw: https://www.genspark.ai/?utm_source=po&utm_campaign=GregIsenberg

    In this solo episode, I share seven tiny, cash-flowing startup ideas you can build with AI in just a few prompts. I walk through how to use Genspark Claw, Genspark's new in-the-cloud agent product running Sonnet 4.6, and demonstrate two ideas I have already built (a dead domain flipper and a local restaurant liquidation broker), build a third idea live on camera (a hiring-signal cold outreach machine), and hand you a five-step framework for generating your own ideas. The goal is simple: give you the creative juices, the framework, and the practical know-how to ship a $200-$1,500/day business with AI as your employee.

    Timestamps

    00:00 – Intro

    01:28 – Idea 1: The Dead Domain Flipper

    06:19 – Idea 2: Local Restaurant Liquidation Broker

    11:03 – Idea 3: Hiring-Signal Cold Outreach Machine (building live)

    14:30 – Prevent Sleep, Heartbeat, and Treating Genspark Claw Like an Employee

    15:52 – Skills, Local File Access, and What Else Genspark Claw Can Do

    17:24 – Reviewing the 14 Personalized Cold Emails It Wrote

    20:35 – More Ideas: Buy-or-Build Memos, Dead Product Hunt SEO, Forgotten Apps

    24:18 – Framework for finding ideas: Public Data, Neglected Assets, Clear Buyer

    26:33 – What Else Comes With Genspark AI Works Base 4.0

    Key Points

    Tiny, boring, cash-flowing ideas beat billion-dollar ideas when you want to ship this month.

    GenClaw plus Slack turns Claude Sonnet 4.6 into an always-on AI employee for around $25/month.

    The repeatable pattern is: messy feed → mispriced asset → trigger event → obvious buyer → liquidity point.

    Three hunting lenses: places of constant change, things people ignore, and assets with clear urgency and spread.

    Talking to your agent in plain English ("strip the HTML entities, make the budget $2,500") replaces most engineering work.

    Selling agents with outcomes is the new SaaS, and shifts the model from per-seat pricing to outcome-based pricing.

    The #1 tool to find startup ideas/trends - https://www.ideabrowser.com

    LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/

    The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/

    #Genspark and #WorkWithGenspark

    FIND ME ON SOCIAL

    X/Twitter: https://twitter.com/gregisenberg

    Instagram: https://instagram.com/gregisenberg/

    LinkedIn: https://www.linkedin.com/in/gisenberg/
  • The Startup Ideas Podcast

    Screensharing How to Start an AI Agent Business Today With Genspark Claw

    11/05/2026 | 30 mins.
    Get started building your tiny AI Agent business with Genspark Claw: https://startup-ideas-pod.link/genspark_

    In this solo episode, I share seven tiny, cash-flowing startup ideas you can build with AI in just a few prompts. I walk through how to use Genspark Claw, Genspark's new in-the-cloud agent product running Sonnet 4.6, and demonstrate two ideas I have already built (a dead domain flipper and a local restaurant liquidation broker), build a third idea live on camera (a hiring-signal cold outreach machine), and hand you a five-step framework for generating your own ideas. The goal is simple: give you the creative juices, the framework, and the practical know-how to ship a $200-$1,500/day business with AI as your employee.

    Timestamps

    00:00 – Intro

    01:28 – Idea 1: The Dead Domain Flipper

    06:19 – Idea 2: Local Restaurant Liquidation Broker

    11:03 – Idea 3: Hiring-Signal Cold Outreach Machine (building live)

    14:30 – Prevent Sleep, Heartbeat, and Treating Genspark Claw Like an Employee

    15:52 – Skills, Local File Access, and What Else Genspark Claw Can Do

    17:24 – Reviewing the 14 Personalized Cold Emails It Wrote

    20:35 – More Ideas: Buy-or-Build Memos, Dead Product Hunt SEO, Forgotten Apps

    24:18 – Framework for finding ideas: Public Data, Neglected Assets, Clear Buyer

    26:33 – What Else Comes With Genspark AI Works Base 4.0

    Key Points

    Tiny, boring, cash-flowing ideas beat billion-dollar ideas when you want to ship this month.

    GenClaw plus Slack turns Claude Sonnet 4.6 into an always-on AI employee for around $25/month.

    The repeatable pattern is: messy feed → mispriced asset → trigger event → obvious buyer → liquidity point.

    Three hunting lenses: places of constant change, things people ignore, and assets with clear urgency and spread.

    Talking to your agent in plain English ("strip the HTML entities, make the budget $2,500") replaces most engineering work.

    Selling agents with outcomes is the new SaaS, and shifts the model from per-seat pricing to outcome-based pricing.

    The #1 tool to find startup ideas/trends - https://www.ideabrowser.com

    LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/

    The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/

    #Genspark and #WorkWithGenspark

    FIND ME ON SOCIAL

    X/Twitter: https://twitter.com/gregisenberg

    Instagram: https://instagram.com/gregisenberg/

    LinkedIn: https://www.linkedin.com/in/gisenberg/
  • The Startup Ideas Podcast

    Hire a team of AI Agents

    08/05/2026 | 41 mins.
    I'm joined again by Imran Muthuvappa to walk through how to build your own AI Chief of Staff using a tool called Nebula. Imran shows me how to spin up specialized agents that handle the work a real chief of staff would do — surfacing team blockers, tracking project status, holding people accountable to offsite vision goals, running daily agenda briefings, and prospecting ICP leads. We also get into mini apps, model selection for cost efficiency, and why personal software is becoming a real category. By the end, the takeaway is clear: every role now has a "work on the job" component where you supervise yourself and offload tasks to agents.

    Links Mentioned:

    Try Nebula: https://startup-ideas-pod.link/nebula

    Precall Agent: https://startup-ideas-pod.link/precall-agent

    Project Status Agent: https://startup-ideas-pod.link/project-status-agent

    Lead Gen Agent: https://startup-ideas-pod.link/lead-gen-agent

    Timestamps:

    00:00 – Intro

    02:13 – What is Nebula

    02:54 – What an AI Chief of Staff Actually Does

    4:26 – Nebula vs OpenClaw vs Hermes

    06:09 – Building the Blockage Radar Agent

    09:47 – Agent Features

    12:04 – Choosing Cheaper Models for Simple Tasks

    13:15 – Building Project Status Agent

    13:53 – Connecting Tools to Agents

    17:38 – Building Vision Tracker Agent

    22:07 – Mini Apps and Personal Software as a New Paradigm

    25:13 – Building a Daily Agenda Agent and Second Brain Integration

    30:25 – Hours Saved vs. Anxiety Reduced for Founders

    33:02 – Building the Lead Gen Prospector Agent

    39:19 – Final Thoughts: Automate Three to Five Things

    Key Points

    An AI Chief of Staff handles the boring executive support work — calendar, email, LinkedIn, project status — so a human can focus on decisions.

    Nebula lets you build, deploy, and share custom agents through a Slack-like interface, where each agent has its own goals, tools, and system prompt.

    Voice input via SuperWhisper or WhisperFlow gets you to roughly 150 words per minute, which Imran calls the biggest productivity lift available right now.

    Cheaper models like the Nebula model handle most chief-of-staff tasks well — reserve frontier models like Opus or Sonnet for deep coding or reasoning work.

    Mini apps inside Nebula are spinnable web dashboards that connect back to your agents — a glimpse of personal software replacing off-the-shelf tools.

    The new skill is judgment: picking which three to five things to automate out of your week.

    The #1 tool to find startup ideas/trends - https://www.ideabrowser.com

    LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/

    The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/

    FIND ME ON SOCIAL

    X/Twitter: https://twitter.com/gregisenberg

    Instagram: https://instagram.com/gregisenberg/

    LinkedIn: https://www.linkedin.com/in/gisenberg/

    FIND IMRAN ON SOCIAL

    X/Twitter: https://x.com/imranye

    Alif: https://alif.build/
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About The Startup Ideas Podcast
Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas
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