GasGasGas - Primary FRCA ’fun’

• GasGasGas - Diamorphine for the FRCA Primary

  In this episode of Gas, Gas, Gas, we dive deep into the pharmacology of diamorphine — also known by its more notorious street name, heroin. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (but sound advice I would argue) and exam-focused clarity.   Show notes at: https://gasgasgas.uk/diamorphine-for-the-frca-primary/  ———————— Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.  

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• GasGasGas - Oxycodone for the FRCA Primary

  Episode Description: In this episode of GasGasGas, we a plunge into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. Aimed at FRCA Primary candidates and anaesthetic trainees, this episode explores oxycodone's mechanism of action, pharmacokinetics, and pharmacodynamics, as well as its clinical indications, side effect profile, and relevance in anaesthesia and acute pain management. We dissect its action on mu-opioid receptors, compare it to morphine and other opioids, and review evidence regarding oral vs intravenous formulations, metabolism via CYP450 enzymes (notably CYP3A4 and CYP2D6), and implications for renal and hepatic impairment. Key FRCA-focused discussions include its use in multimodal analgesia, potential for respiratory depression, and issues of dependence and controlled drug legislation. Show notes at: https://gasgasgas.uk/oxycodone-frca-primary/ ———————— Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.  

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• GasGasGas - Methadone for the FRCA Primary

  In this episode of the GasGasGas Primary FRCA podcast, we explore methadone—its pharmacology (pharmacodynamics and pharmacokinetics), diverse receptor activity, and its clinical uses. While traditionally associated with managing opioid dependency, methadone’s unique pharmacodynamics and potential utility may have been overlooked given its other uses…   Show notes at: https://gasgasgas.uk/episode-24-methadone-for-the-frca-primary/ ———————— Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.  

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• GasGasGas - Tramadol for the FRCA Primary Exam

  This episode takes a dive into the detailed pharmacology of Tramadol focussing on the content to understand for the FRCA Primary exam. We explore its unique multi mechanism analgesic action, pharmacokinetics, clinical uses, and key points. #Tramadol #Pharmacology #FRCAprep #Opioids #MultimodalAnalgesia #GasGasGasPodcast ———————— Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.

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  12:28
• GasGasGas - Alfentanil for the FRCA Primary Exam

  In this episode of GasGasGas, we explore Alfentanil, a short-acting μ-opioid receptor agonist pivotal for anaesthetic practice. Discovered in 1976 by Janssen Pharmaceuticals, Alfentanil remains a super handy agent, especially for (modified) rapid-sequence inductions and acute pain management.   Show notes at https://gasgasgas.uk/alfentanil-for-the-frca-primary/  ———————— Dr Gas Lurks on:  BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X FaceBook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ———————— We have a catalogs of Podcast and Vivacast episodes here!  Primary FRCA Podcast Catalog Primary FRCA VivaCast Catalog ———————— #FOAMed #frcaprimary #frca #Anaesthetics #Anaesthesia  #Pharmacology #Physiology A Primary FRCA podcast ———————— Want to have a chat? james@gasgasgas.uk  ———————— Disclaimer / Sage Advice All content is educational in nature, but is never intended to be acted upon independent of organised educational and training structures, and under appropriate supervision for your stage of training.  This information is not a suitable substitute for medical advice and requests for medical advice will not be acted upon. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the author, numerical ranges for technical data and references where reasonable will be present.  

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