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The Holistic GLP-1 Podcast with Elizabeth McGann

Elizabeth McGann
The Holistic GLP-1 Podcast with Elizabeth McGann
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  • #48 - The Hidden Heart Benefits of GLP-1s (with Dr. Ralph DeFronzo)
    In this breakthrough episode, Dr. Ralph DeFronzo—one of the most respected names in metabolic health—joins Elizabeth to discuss the real story behind GLP-1 medications. If you’ve ever wondered: Do I have to stay on GLP-1s forever? Are lower doses (or “microdoses”) actually effective? Can I activate GLP-1 naturally—without prescriptions? Is it really safe for long-term use? …this episode gives you honest answers, straight from an expert who helped define modern diabetes treatment. Dr. D explains how GLP-1s not only facilitate weight loss by reducing one’s appetite, but also protect your heart, liver, brain and kidneys—and why most people overlook this crucial benefit. You’ll learn what makes someone a “super responder,” the link between cortisol and weight loss resistance, and how to finally quiet “Food Noise” for good. ✨   *** CLICK HERE TO GET ==>  FREE "Freedom From Food Noise" Masterclass: https://go.elizabethmcgann.com/start ***   SHOW NOTES: [ 00:00 ] Introduction [ 01:45 ] GLP-1s: Not just for weight loss—they also protect your heart, liver, kidneys & brain [ 03:40 ] People often forget: GLP-1s were originally created to treat diabetes [ 07:35 ]  Are low doses (aka “microdosing”) effective? DeFronzo’s take on trending wellness practices [ 10:55 ] Significant benefits of GLP-1s for non-diabetics [ 13:25 ] How much weight do you really need to lose to help your heart? The 10% threshold explained [ 15:55 ] “Weighted” Question: Once on them, do you need to be on GLP-1s forever? The real answer from an expert who knows [ 19:30 ] Why diet and exercise alone don’t work long-term for most people—and what actually does work [ 22:30 ] Can you “reverse” diabetes or insulin resistance naturally? The symptoms, YES... but it’s complicated! [ 25:00 ] How GLP-1s reduce inflammation and rewire your metabolism at the cellular level [ 28:00 ] The truth about “natural” GLP-1 boosters like berberine, fiber and protein [ 31:00 ] Dr. DeFronzo’s surprising eating habit—and what it reveals about fasting myths [ 35:00 ] How GLP-1s may help food addiction by rewiring brain circuitry [ 39:45 ] Insights from four-year safety data: What we do and don’t know about long-term use [ 42:00 ] Black box warnings and thyroid cancer risk—what’s real and what’s hype? [ 44:50 ] Can someone taper off of GLP-1s successfully? Who are the 10–15% that do—and how? [ 49:00 ] Will future GLP-1s render current meds obsolete? Why retatrutide may change the game [ 56:00 ] Super-responders vs. non-responders—and the cortisol connection you’ve never heard [ 59:00 ] Why Dr. DeFronzo thinks the next big breakthrough will be insulin-sensitizers [ 01:02:00 ] Final thoughts: a hopeful but cautionary note about access, cost and a new generation of GLP-1s on the way   *** 🔗 Mentioned in This Episode: Learn how to activate GLP-1 naturally and silence cravings! CLICK HERE TO GET ⇒ Free Masterclass: Freedom From Food Noise: https://go.elizabethmcgann.com/start   ***   Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann   *** Learn more about Dr. Ralph DeFronzo: University of Texas Health San Antonio Bio : https://directory.uthscsa.edu/academics/profile/defronzo Appearance on Dr. Peter Attia’s THE DRIVE Podcast: https://www.youtube.com/watch?v=vYQaLV3Fm00 Dr. DeFronzo’s Work: Just Google him—you’ll find over 900 scientific publications!
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  • #47 - GLP-1's Secret Ally: No Sugar (with Michael Collins)
    Could sugar be the real addiction holding you back on your GLP-1 weight loss journey? Join host Elizabeth McGann and “The Sugar-Free Man” Michael Collins—founder of SugarAddiction.com and the Quit Sugar Summit—for an unfiltered look at why cutting sugar might be the fastest path to healing your metabolism, resetting your hormones and getting off GLP-1 drugs for good. Michael shares the shocking truth about how sugar lights up the same brain pathways as cocaine, why it’s not just willpower, and how 41,000+ people have successfully detoxed with his protocol. Whether you're currently on a full GLP-1 prescription, microdosing, all-natural or simply curious, this episode will change how you think about cravings, Food Noise and what your body actually needs to release weight.   🎯 In This Episode You’ll Learn: Why GLP-1 meds are just a tool—and how to wean off them naturally The shocking truth about how sugar hijacks your brain What counts as “sugar” (spoiler: it’s more than cookies) How to detox safely and finally end "Food Noise" The link between sugar, trauma, and emotional self-soothing     SHOW NOTES [ 01:44 ] Meet Michael Collins, the “Sugar-Free Man” who’s helped over 41,000 people break free from sugar’s grip—without shame or willpower wars. [ 02:22 ] Raised on sugar, numbing with it for years, and then getting sober—Michael shares how emotional pain often hides in plain sight…in your cravings. [ 04:24 ]  Food noise, food guilt, and food obsession—where it really comes from and why your brain might be hardwired to seek sugar. [ 05:52 ] The uncomfortable truth: sugar acts like a drug in the brain. Here’s how it hijacks your mood, your hormones, and your ability to feel full. [ 09:33 ] Two-thirds of the population is hooked—but no one wants to admit it. Michael breaks down the real numbers and what people are too ashamed to say out loud. [ 13:41 ] Backed by science: sugar lights up the same brain pathways as cocaine. The reward loop is real—and you can’t think your way out of it. [ 15:05 ] Mental fog, low energy, and memory issues? Sugar might be shrinking your brain. Metabolic psychiatry is rewriting the conversation on addiction and aging. [ 17:33 ] Why sugar isn’t just cookies. It’s hidden in “healthy” foods—fruit juice, bread, potatoes, dried fruit. If you’ve quit sweets but still feel cravings, this is why. [ 20:16 ] How 5-year-olds are ending up with fatty liver—and what that means for your hormones, metabolism and longevity. [ 23:40 ] You think you’re being “good” by cutting back—but even small amounts of sugar can trigger a cascade that sets you back. Why abstinence is easier than moderation. [ 30:03 ] For some, GLP-1 can be a useful bridge. But real freedom comes when the sugar cravings disappear and the dose drops—or disappears too. [ 31:28 ] The detox that’s changed lives: no sugar, no flour, and no caffeine (yep, caffeine too) for 30 days. And why it works when nothing else does. [ 35:29 ] What to eat instead. The power of whole foods, healthy fats and removing the biochemical noise so your body can regulate hunger naturally. [ 39:10 ] Some foods keep your cravings on life support. What you need to know about nuts, dairy, and even fruit once you’re deep into your healing. [ 44:30 ] The deeper reason weight returns after success. If you’ve ever thought, “Why can’t I just stay on track?”—you'll need to hear this part. [ 49:00 ] This isn’t a diet. It’s a path to healing your brain, stabilizing your mood, and remembering who you are without the daily sugar hit. [ 52:16 ] Want to take the first step? Visit QuitSugarSummit.com to join Michael’s sugar detox or find group coaching.      *** CLICK HERE TO GET ==>  FREE "Freedom From Food Noise" Masterclass: https://go.elizabethmcgann.com/start     *** Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann       Learn more about: Michael Collins, “The Sugar-Free Man” Website: https://sugaraddiction.com/ Instagram: https://www.instagram.com/realsugarfreeman/?hl=en The Last Resort Sugar Detox Book on Amazon: https://www.amazon.com/Last-Resort-Sugar-Detox-Guide/dp/172922329X
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  • #46 - Microdosing GLP-1: Muscle, Metabolism & Sustainable Weight Loss (w/ Dr. Jaime Schehr)
    What if your weight loss journey could be both powerful and sustainable—without sacrificing your body's muscle mass, metabolism or equilibrium? In the latest episode of The Holistic GLP-1 Podcast, Elizabeth sits down with Dr. Jaime Schehr, a nationally recognized naturopathic doctor and registered dietitian, to unpack the truth about using GLP-1 medications holistically. Together they explore how to microdose GLP-1 medications to avoid muscle loss; why supporting your body naturally is crucial (whether on the medication or not); and how real change comes from self-awareness—not shortcuts. You'll also learn why Food Noise happens, how to quiet it naturally, and what to prioritize if you're serious about sustainable, body-loving weight release long term. If you're a woman in perimenopause or menopause looking for a natural, soul-aligned path to weight loss, this episode is for you.✨   *** CLICK HERE TO GET ==>  FREE "Freedom From Food Noise" Masterclass: https://go.elizabethmcgann.com/start   *** SHOW NOTES: [ 00:00 ] Intro: Mind, Body & Soul Weight Release with Elizabeth [ 01:20 ] Redefining GLP-1: Not just about fast weight loss—it's about metabolic healing [ 02:20 ] Dr. Jaime’s first exposure to GLP-1 medications during the pandemic—and the “Hail Mary” experience that changed her mind about it [ 04:10 ] Why standard diets fail women in midlife, the perils of a “diet culture” and what everyone must understand about hormonal health [ 06:40 ] Activating your natural GLP-1: Fiber, gut health, strength training and strategic supplementation [ 08:00 ] Why fatigue—not nausea—is the biggest reason people fail on GLP-1 medications [ 10:30 ] Optimizing blood sugar balance: The key behind sustainable fat loss (with GLP-1s or not) [ 13:20 ] How low-carb eating supports microdosing success—and why ketogenic diets are challenging   [ 17:00 ] Behavior change secrets: Why self-awareness is the foundation of lasting health   [ 20:30 ] How to protect lean muscle mass while using GLP-1 (hint: strength training + protein!)   [ 24:00 ] The dangers of high-dose GLP-1 regimens and crash weight loss   [ 26:20 ] Using GLP-1 as a support tool, not a crutch—not simply for “fast weight loss” as most people think   [ 29:20 ] Understanding Food Noise whether on or off GLP-1 medications: Is it just based on glucose spikes?   [ 33:30 ] Dr. Schehr’s experience with patients getting off of GLP-1 medications   [ 36:00 ] Finding the minimum effective dose—not the standard pharmaceutical prescription   [ 38:00 ] How Bio.me supplements help support gut health, metabolism and GLP-1 weight loss success   [ 41:00 ] The return to community, in-person wellness and holistic empowerment after the pandemic   [ 42:45 ] The next 18 months, where to find Dr. Jaime Schehr and continue learning     *** CLICK HERE TO GET ==>  FREE "Freedom From Food Noise" Masterclass: https://go.elizabethmcgann.com/start     *** Get Connected with Elizabeth McGann: Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann     Learn more about Dr. Jaime Schehr: Website: https://www.jaimeschehr.com/ Instagram: https://www.instagram.com/jaimeschehr/?hl=en Bio.me Website: https://bio.me/
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  • #45 - Hormone Therapy + GLP-1: The New Midlife Rx (with Dr. Suzanne Lenz)
    In this action-packed episode, Elizabeth sits down with Dr. Suzanne Gilberg-Lenz to unpack the biggest misconceptions surrounding menopause, and introduce the concept of using GLP-1 medications in chorus with hormone replacement therapy for positive health (and weight-release) outcomes. An OB/GYN, Integrative Health Practitioner and author of Menopause Bootcamp, Dr. Suzanne’s insights sound like a battle cry for women to optimize their health and empower themselves and flourish as they age. Throughout the high-energy discussion, Elizabeth and Dr. Suzanne discuss the biggest myths about menopause, and dive into the real deal about HRT—what works, what doesn’t, and what you need to know if you’re thinking about adding it to your GLP-1 journey. If you’re interested in a holistic approach to GLP-1s, this combo could be a game changer—not just for weight loss, but for inflammation, energy and even long-term brain health. As Dr. Suzanne says, we seem to have entered the Wild West of discovering the full potential of GLP-1 agonist medications. So if you’ve been wondering how to feel better, think clearer, and actually release weight—body, mind, and soul—you’re going to want to give this one a listen! *** CLICK HERE TO GET ==>  FREE MASTERCLASS - "Freedom From Food Noise": https://go.elizabethmcgann.com/start *** SHOW NOTES [ 00:00 ] Meet Dr. Suzanne Gilberg-Lenz, OB/GYN, integrative health pioneer, menopause educator and fierce truth-teller. [ 01:50 ] Not a pathology or a disease: breaking the biggest myths surrounding menopause [ 03:00 ] Hormone Therapy as an effective tool for menopause-age women, but not for everyone [ 05:00 ] About Menopause Bootcamp, the book and the women’s health movement [ 08:50 ] Hormone Therapy, bioidenticals, and taking a nutritional vs. HRT approach: what’s safe, what’s hype, and what every woman needs to know before choosing. [ 13:00 ] “I’m Doing Everything Right, But Still Struggling—Now What?” When lifestyle isn't enough and when to consider HRT [ 17:40 ] Why You Can’t Find a Good Menopause Doctor [ 23:00 ] Why Women Gain Belly Fat in Midlife (It’s Not Your Fault): the old dieting tricks no longer work when you are shifting into a new metabolism [ 27:00 ] Using GLP-1 medications and Hormone Therapy synergistically: What Dr. Suzanne thinks about semaglutide, longevity and the “wild west” of peptides. [ 30:15 ] Natural GLP-1 Support & the Role of Botanicals: how herbs and plants can support the journey—but aren’t always a replacement. [ 32:34 ] What Dr. Suzanne Really Thinks About the Politics of Healthcare and Women’s Health: a fiery take on the current cabinet picks, deregulation and reproductive rights. [ 36:00 ] The next 18 months: what’s next for Dr. Suzanne, her new practice launch, upcoming retreats and where to follow her online. *** Get Connected with Elizabeth McGann: CLICK HERE TO GET ==>  FREE MASTERCLASS - "Freedom From Food Noise": https://go.elizabethmcgann.com/start Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann     Learn more about Dr. Suzanne Gilberg Lenz: Website: https://thedrsuzanne.com/ Instagram: https://www.instagram.com/askdrsuzanne/ Menopause Bootcamp on Amazon: https://www.amazon.com/Menopause-Bootcamp-Optimize-Empower-Flourish/dp/0063143186
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  • #44 - Natural GLP-1 Activation & Avoiding the "Seven Cs" (with Dr. Stan Guberman)
    In this episode of The Holistic GLP-1 Podcast, we are joined by the wonderful Dr. Stan Guberman, a licensed Chiropractic Physician and Certified Acupuncturist who holds two Diplomas in Nutrition that he’s put to excellent use over a 40-year career. I first discovered Dr. Guberman about a year ago when I was dealing with a health challenge and was looking for holistic solutions. I was so impressed by his wealth of naturopathic knowledge I just knew I had to share him with you. Throughout the discussion, Dr. G helps us consider natural alternatives to GLP-1 medications for weight loss purposes—including gems like Berberine and Yerba Mate tea. We also explore the optimal kind of diet and dietary supplements one could strongly consider when following a holistic GLP-1 program. As well as the so-called “Seven Cs” to avoid. Guberman wisely cautions against the notion of viewing GLP-1 treatments as a panacea to America’s obesity epidemic—reminding us that without a strong focus on the four pillars of sensible nutrition, most of the weight loss achieved by GLP-1 patients is likely to be fleeting and therefore unsuccessful. We cover some amazing ground on this podcast, including the very hot topic of micro-dosing GLP-1’s—that is utilizing only a “minimum effective dose” of these peptides for the healthiest and most long-term, sustainable benefits. So let’s get into it! *** CLICK HERE TO GET ==>  FREE MASTERCLASS - "Freedom From Food Noise": https://go.elizabethmcgann.com/start *** SHOW NOTES 00:00 – Intro: The “7 Cs” to Avoid While Taking GLP-1 Medications 02:52 – Big Pharma vs. Natural Medicine: Will RFK Jr. be a game-changer to the toxic food industry? The battle against processed food and chemical additives. 04:48 – The Truth About Our Food Supply: Why U.S. food is laced with harmful chemicals & how Europe is leading the way in banning toxic additives. 06:44 – How to Choose the Right Supplements: Why blindly buying supplements at Whole Foods could be a mistake. 08:03 – Are You Addicted to Food? The truth about "food noise" and how to naturally rebalance hunger hormones like GLP-1. 10:53 – Why Big Pharma Fears Nutrition: How natural alternatives like berberine and Yerba Mate could replace prescription drugs. 13:45 – The Hidden Dangers of Organic Foods: What you should know before buying organic & why hydroponics might be a better option. 16:05 – GLP-1 Medications & America’s Obesity Crisis: The shocking truth about how much money is  spent on weight loss drugs with an ongoing obesity epidemic. 19:18 – The Case for Microdosing GLP-1: Why smaller doses, combined with lifestyle changes, may be the key to sustainable weight loss. 21:36 – Natural GLP-1 Boosters: How to enhance weight loss with supplements like berberine, Yerba Mate, and fiber. 24:07 – What Your Bloodwork Says About Your Health: The key markers to watch for metabolic health, inflammation and vitamin deficiencies. 29:08 – The Menopause & Perimenopause Puzzle: Why hormone balancing has become unnecessarily complicated & nutritional recommendations 32:36 – The Best Natural Hormone Balancers: Should you microdose bioidentical hormones? A look at Phyto B, Siberian rhubarb, and natural alternatives. 35:25 – Ideal progression of treatment from “What are your symptoms?” to “What were your symptoms?” 39:51 – The Future of Cancer & Functional Medicine: Exciting research on alternative therapies, including venus fly trap extract & infrared therapy. 42:21 – Should Dr. Guberman start a podcast? He considers launching his own show & Elizabeth shares tips on getting started. 44:16 – Dr. Guberman’s Supplements for top-rated holistic health solutions. *** Get Connected with Elizabeth McGann: CLICK HERE TO GET ==>  FREE MASTERCLASS - "Freedom From Food Noise": https://go.elizabethmcgann.com/start Coaching Website: http://www.ElizabethMcGann.com Instagram: http://www.instagram.com/elizabethmcgann Facebook: https://www.facebook.com/ElizabethMcGannWellness LinkedIn: https://www.linkedin.com/in/elizabethmcgann X/Twitter: https://twitter.com/ElizabethMcGann   Learn more about Dr. Stan Guberman: Website: https://www.drguberman.com/ Facebook: https://www.facebook.com/drguberman Instagram: https://www.instagram.com/dr.stanguberman/ X/Twitter: https://x.com/DrGuberman
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About The Holistic GLP-1 Podcast with Elizabeth McGann

Without a doubt, GLP-1 medications have revolutionized the weight loss discussion in the U.S. and throughout the world since many first heard about them in 2022. On The Holistic GLP-1 Podcast, Elizabeth McGann explores the latest breakthroughs and concerns about applying GLP-1 weight loss technology with a holistic approach that balances the critical dimensions of body, mind & Soul. The podcast explores essential topics, including how a medication originally developed for the treatment of diabetes has rapidly turned into arguably the most profoundly impactful weight loss medication in history; how microdosing GLP-1 medications under a doctor’s care may be a more effective weight loss strategy than the pharmaceutically recommended dose; the specific needs of perimenopause and menopause age women; and endogenous ways to stimulate the GLP-1 hormone naturally in the body without medication. Among the top 5% of podcasts listened to internationally, The Holistic GLP-1 Podcast consistently ranks as the #1 show on Apple Podcasts and Spotify on the topic of GLP-1 weight loss medications worldwide. Follow Elizabeth @ElizabethMcGann on Instagram Subscribe to The Holistic GLP-1 Podcast with Elizabeth McGann and share the show with someone who needs to hear it.
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