In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomonas such a tricky bugger to treat! Support the showQuestions, comments, suggestions to [email protected] or Tweet us @IDiots_podPrep notes for completed episodes can be found here: https://idiots.notion.site/ID-IOTS-Prep-Notes-cf9b043fbb5a41309e15270f6079abf5?pvs=4(Not all episodes have prep notes)If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

It was a long time coming, but it’s here. Jame and Callum set off on our mini-series, Nobbling the Nonfermentors, starting with an introduction to glucose-nonfermenting organisms before moving on to the biggie: Pseudomonas aeruginosa! Part 2 next week covers treatment of Pseudomonas, including a deep dive into Pseudomonas resistance mechanisms. Stay tuned!Support the showQuestions, comments, suggestions to [email protected] or Tweet us @IDiots_podPrep notes for completed episodes can be found here: https://idiots.notion.site/ID-IOTS-Prep-Notes-cf9b043fbb5a41309e15270f6079abf5?pvs=4(Not all episodes have prep notes)If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Jame and Callum were delighted to be invited as guests to the podcast Microbe Mail by host Vindana (Vin) Chibabhai. Check out the Microbe Mail podcast:https://microbemail.captivate.fm/  @microbemail We discuss how bactericidal and bacteriostatic are defined, what the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) are and why this isn't as simple as it first seems. We then discuss specific clinical situations and where bactercidal vs static have been compared. Links/papers mentioned in this episode:The basics of beta lactamasesWald-Dickler N, Holtom P, Spellberg B. Busting the Myth of ‘Static vs Cidal’: A Systemic Literature Review. Clin Infect Dis. 2018 17;66(9):1470–4.Use of bacteriostatic agents in Neutropenic fever: The RCT referred to in the abstract is here: Jaksic B, Martinelli G, Oteyza JP, Hartman CS, Leonard LB, Tack KJ. Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer. Clinical Infectious Diseases. 2006 Mar 1;42(5):597–607Support the showQuestions, comments, suggestions to [email protected] or Tweet us @IDiots_podPrep notes for completed episodes can be found here: https://idiots.notion.site/ID-IOTS-Prep-Notes-cf9b043fbb5a41309e15270f6079abf5?pvs=4(Not all episodes have prep notes)If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Jame and Callum are together in person to talk about the importance of keeping your house in order. Being an infection specialist does not automatically make you an antimicrobial steward. We reflect on some challenges to being an antimicrobial steward  when practising infection medicineThe choosing wisely campaign mentioned by Jame:https://www.choosingwisely.org/ A course on Antimicrobial Stewardship which is a good starting point:https://www.futurelearn.com/courses/antimicrobial-stewardship The IDSA guidance on AmpC production risk organisms mentioned by Jame:https://www.idsociety.org/practice-guideline/amr-guidance/#AmpC%CE%B2-Lactamase-ProducingEnterobacteralesSupport the showQuestions, comments, suggestions to [email protected] or Tweet us @IDiots_podPrep notes for completed episodes can be found here: https://idiots.notion.site/ID-IOTS-Prep-Notes-cf9b043fbb5a41309e15270f6079abf5?pvs=4(Not all episodes have prep notes)If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

We were delighted to be joined by Dr Anastasia "Tash" Theodosiou to talk about breastfeeding, antibiotics and the risks of antibiotic harm to mum and baby. Tash is an infectious diseases/medical microbiology trainee, host of the HelloMicro blog and has volunteered as a Breastfeeding Peer Supporter.*Note the NICE guidelines have been updated and do not recommend trimethoprim in any stage of pregnancySupport the showQuestions, comments, suggestions to [email protected] or Tweet us @IDiots_podPrep notes for completed episodes can be found here: https://idiots.notion.site/ID-IOTS-Prep-Notes-cf9b043fbb5a41309e15270f6079abf5?pvs=4(Not all episodes have prep notes)If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod