Intelligent Medicine

Resveratrol + Copper Research, Plus Grain-Free Strategies for Stalled Weight Loss: Leyla Muedin, a registered dietitian nutritionist, answers listener emails. She reviews a small India study (BJC Reports, published September 30, 2025) in which 10 glioblastoma patients awaiting surgery received resveratrol (5.6 mg) and copper (560 ng) four times daily for about 11.6 days, compared with 10 controls; the combination generated reactive oxygen species that deactivated cell-free chromatin particles in the tumor microenvironment and reduced cancer hallmarks. Asked whether this could be prophylactic against cancer, she says it is unknown and requires replication in larger studies, advising supplement use be discussed with a practitioner. She then addresses grain elimination for stalled weight loss: replace grains with more meat and non-starchy vegetables, think beyond typical breakfast foods by using leftovers, and use small portions of starchy vegetables (e.g., squash or potato) if starch helps sleep. She recommends investigating root causes of anxiety and poor sleep and suggests moderation for foods like oatmeal.

A correction from a previous podcast episode
Congratulations on 40 years!
Quinoa is not a grain—it's a pseudograin
When did poisoning our food fall under 'defense'? How does MAHA reconcile this?

I have increased pressure in my eyes, leading to glaucoma. Is there any way to avoid this?
Can the long-term effects of chemo cause insomnia and nausea?
What do you think of flow drops?  
I avoid red meat. Would I still get the same benefits from seafood and turkey?
What's the best way to take Endefen powder?

Free Speech, Cancel Culture, and the Mental Health Benefits of Speaking Up: Clinical psychologist Dr. Chloe Carmichael, author of “Can I Say That? Why Free Speech Matters and How to Use It Fearlessly,” frames free expression as a mental health and problem-solving issue amid rising polarization, self-censorship, and cancel culture. Carmichael says authentic speech deepens cognition, aids emotional regulation, and strengthens social support, while chronic suppression can lead to repression, denial, anxiety, depression, and resentment. She describes fear and professional risk after publicly opposing child masking during COVID and argues that labeling speech as “violence” distorts reality, though true threats and incitement differ from words. She distinguishes self-censorship from healthy restraint, offers the WAIT test (Want, Appropriate, Inoculate, Trust), and discusses groupthink, innovation, misinformation debates, time-place-manner limits, and examples from corporate and university settings.

Dr. Hoffman continues his conversation with clinical psychologist Dr. Chloe Carmichael, author of “Can I Say That? Why Free Speech Matters and How to Use It Fearlessly.”