Medscape InDiscussion: Hidradenitis Suppurativa

Join Drs Okoye and Lawson as they explore the intersection of HS in dermatology and ob/gyn, from hormone shifts to biologics, and why partnership is key for better outcomes.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002311. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Hidradenitis Suppurativa https://emedicine.medscape.com/article/1073117-overview
A Guide to the Management of Hidradenitis Suppurativa in Pregnancy and Lactation https://pubmed.ncbi.nlm.nih.gov/40131719/
Comedones in Dermatology https://pubmed.ncbi.nlm.nih.gov/38595018/
The Role of Androgens and Estrogens in Hidradenitis Suppurativa - A Systematic Review https://pubmed.ncbi.nlm.nih.gov/28128074/
Systemic Lupus Erythematosus (SLE) https://emedicine.medscape.com/article/332244-overview
Hormonal Contraceptives and Dermatology https://pubmed.ncbi.nlm.nih.gov/32894455/
Polycystic Ovarian Syndrome https://emedicine.medscape.com/article/256806-overview
Current Treatments and Future Directions for Hidradenitis Suppurativa: A Narrative Review of Completed and Ongoing Phase 3 Clinical Trials of Biologic Therapies https://pubmed.ncbi.nlm.nih.gov/40681937/
Pregnancy and Multiple Sclerosis: An Update https://pubmed.ncbi.nlm.nih.gov/34310364/
Outcomes of Pregnancy and Childbirth in Women With Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/34153386/
The Psychosocial Effects of Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/40381968/

Explore evidence-based antibiotic regimens for HS with Dr Cohen. Learn how targeted antimicrobial strategies can improve outcomes in complex cases.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002310. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Hidradenitis Suppurativa https://emedicine.medscape.com/article/1073117-overview
Efficacy and Safety of Biologics for Hidradenitis Suppurativa: A Network Meta-Analysis of Phase III Trials https://pubmed.ncbi.nlm.nih.gov/40062409/
Antibiotic, Hormonal/Metabolic, and Retinoid Therapies for Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/39626998/
Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/37556513/
Antiandrogen Therapy in Hidradenitis Suppurativa: Finasteride for Females https://pubmed.ncbi.nlm.nih.gov/34260109/
Combination Therapy With Clindamycin and Rifampicin for Hidradenitis Suppurativa: A Series of 116 Consecutive Patients https://pubmed.ncbi.nlm.nih.gov/19590173/
Pharmacokinetic Interaction Between Rifampicin and Clindamycin in Staphylococcal Osteoarticular Infections https://pubmed.ncbi.nlm.nih.gov/37302771/
Rifampin-Moxifloxacin-Metronidazole Combination Therapy for Severe Hurley Stage 1 Hidradenitis Suppurativa: Prospective Short-Term Trial and 1-Year Follow-Up in 28 Consecutive Patients https://pubmed.ncbi.nlm.nih.gov/31931082/
Efficacy and Durability of Intravenous Ertapenem Therapy for Recalcitrant Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/38353987/
The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/34239882/
Surgical Approach to Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/39961528/

Join surgeon Dr Julie Caffrey as she shares her approach to hidradenitis suppurativa surgery, from patient selection to excision, reconstruction, and reducing recurrence.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002309. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Hidradenitis Suppurativa: A Review of Post-operative Outcomes https://pubmed.ncbi.nlm.nih.gov/32868233/
Negative Pressure Wound Therapy in Patients With Wounds Healing by Secondary Intention: A Systematic Review and Meta-Analysis of Randomised Controlled Trials https://pubmed.ncbi.nlm.nih.gov/33038929/
Efficacy and Durability of Intravenous Ertapenem Therapy for Recalcitrant Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/38353987/
Surgical Treatment of Suppurative Hidradenitis https://www.sciencedirect.com/science/article/abs/pii/S0007122653800317
Hidradenitis Suppurativa and Squamous Cell Carcinoma: A Systematic Review of the Literature https://pubmed.ncbi.nlm.nih.gov/37545826/
Pseudoepitheliomatous Hyperplasia: A Clinical Entity Mistaken for Squamous Cell Carcinoma https://pubmed.ncbi.nlm.nih.gov/25722605/

What if your HS patient's normal labs are hiding a metabolic storm? Drs Okoye and Bordone explore overlooked clues, HOMA-IR, and real-world GLP-1 outcomes.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002308. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Assessing Insulin Sensitivity and Resistance in Humans https://pubmed.ncbi.nlm.nih.gov/25905189/
HOMA-IR Online Calculator https://emedicine.medscape.com/article/122501-workup?form=fpf
Aural Sign of Coronary-Artery Disease https://pubmed.ncbi.nlm.nih.gov/4718047/
Exploring the Therapeutic Potential of GLP-1 Agonists in Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/40196946/
Risk of Liver Dysfunction and Non-Alcoholic Fatty Liver Diseases in People With Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis of Real-World Evidences https://pubmed.ncbi.nlm.nih.gov/36591267/
Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis With Liver Fibrosis https://pubmed.ncbi.nlm.nih.gov/38856224/
FIB-4 Score https://reference.medscape.com/calculator/326/fib-4-for-noninvasive-diagnosis-of-hepatic-fibrosis
The Therapeutic Potential of GLP-1 Receptor Agonists in the Management of Hidradenitis Suppurativa: A Systematic Review of Anti-Inflammatory and Metabolic Effects https://pubmed.ncbi.nlm.nih.gov/39518431/

Join Dr Ginette Okoye and Dr Tamia Harris-Tryon as they explore the science behind the gut and skin microbiomes in HS, and how sugar, fiber, and fermented foods may influence outcomes.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002307. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Microbiota and Maintenance of Skin Barrier Function https://pubmed.ncbi.nlm.nih.gov/35617415/
Evaluating Dietary Considerations in Hidradenitis Suppurativa: A Critical Examination of Existing Knowledge https://pubmed.ncbi.nlm.nih.gov/38406977/
Role of Dietary Fiber in the Recovery of the Human Gut Microbiome and Its Metabolome https://pubmed.ncbi.nlm.nih.gov/33440171/
Mediterranean Diet Intervention Alters the Gut Microbiome in Older People Reducing Frailty and Improving Health Status: The NU-AGE 1-Year Dietary Intervention Across Five European Countries https://pubmed.ncbi.nlm.nih.gov/32066625/
Population-Level Gut Microbiome and Its Associations With Environmental Factors and Metabolic Disorders in Southwest China https://pubmed.ncbi.nlm.nih.gov/39905038/
Seasonal Variation in Human Gut Microbiome Composition https://pubmed.ncbi.nlm.nih.gov/24618913/
Dynamics and Stabilization of the Human Gut Microbiome During the First Year of Life https://pubmed.ncbi.nlm.nih.gov/25974306/
Skin and Gut Microbiome in Hidradenitis Suppurativa: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/37626773/
Cigarette Smoking as a Triggering Factor of Hidradenitis Suppurativa https://pubmed.ncbi.nlm.nih.gov/10393449/
Probiotics in Hidradenitis Suppurativa: A Potential Treatment Option https://pubmed.ncbi.nlm.nih.gov/34236727/
Oldways Cultural Food Traditions www.oldwayspt.org