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In this MedEvidence rebroadcast, Dr. Albert Lopez explains lipoprotein(a), a genetically determined heart disease risk factor which still strikes people with “good” cholesterol. He also explains that plaque behaves like an inflammatory volcano that can rupture without warning. Dr. Lopez goes into how lipoprotein(a) increases the risk of heart attack, stroke, and aortic valve disease. Dr. Lopez then hammers home how important testing for Lp(a) is, especially for those at an increased risk.
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Cardiologist and Clinical Researcher Dr. Michael Koren joins Eric Ross from "What the Health Just Happened" to talk about a wide range of topics. They discuss the history of clinical research in healthcare, the changing landscape of research in America and around the world, what's healthy (and what's not) in popular culture, and the emerging field of gene editing. They even talk about Dr. Koren's misadventures trying to get tickets to the FIFA World Cup!
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Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com

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Dr. Michel Koren and Dr. Mitchell Rothstein host a presentation in front of a live audience to discuss the current state of gene editing. The doctoral duo discuss developments including new-to-market medical therapies, clinical trials, and the legal issues surrounding gene therapy patents. They also explain the difference between gene silencing techniques, which temporarily stop genes from creating proteins, and gene editing techniques which permanently alter the genome. They also touch on controversies, risks, and the comprehensive considerations that take place before a participant can partake in a gene editing clinical trial.
Be a part of advancing science by participating in clinical research.

Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com

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Music: Storyblocks - Corporate Inspired

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Dr. Robin Blackstone joins Dr. Mitchell Rothstein to talk about the intersection of technology, empathy, and the healthcare system. The doctoral duo discuss the emerging role of AI in healthcare and how specialized, individualized, non-chatbot systems may be able to sift through the masses of health data that plague doctors to provide individualized, patient-specific recommendations and revelations. The two also briefly discuss the history of healthcare in order to present Dr. Blackstone's vision for the future, Health 4.0. They finish the discussion with more details about Dr. Blackstone's Public Benefit Corporation, The H4 Alliance Trust, a 5013c project focusing on a person-centered health system. Find more about the H4 Alliance Trust at h4alliancetrust.org
Be a part of advancing science by participating in clinical research.

Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com

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Music: Storyblocks - Corporate Inspired

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Join internist and cholesterol expert Albert Lopez, DO, FACP, FASPC, as he reviews the new 2026 Cholesterol Guidelines. In this segment, he focuses on new risk assessment guidelines, including the genetic risk factor Lipoprotein(a) and a sign of damage, the CAC score, and the recommendation that risk assessment starts much younger, around 30 years old. He discusses treatment options for high cholesterol, including sound evidence for statins and newer treatments for rare cholesterol manifestations.
Be a part of advancing science by participating in clinical research.

Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com

Listen on Spotify
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Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.

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Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com

Music: Storyblocks - Corporate Inspired

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