In this episode of the Full of Beans Podcast, I’m joined by Professor Hubertus Himmerich, Consultant Psychiatrist and Reader in Eating Disorders at King’s College London, and the principal investigator of the EDEN study.
The EDEN study is the first study of its kind exploring whether low-dose oral ketamine, compared with placebo, could support people living with both anorexia nervosa and major depressive disorder.
Depression affects around 50% of people with anorexia, and when low mood, anxiety and hopelessness are present, it can make recovery feel incredibly difficult. Traditional antidepressants often don’t work well for people with anorexia, which is why researchers are exploring new approaches.
What We Cover in This Episode
Why is depression so common in anorexia nervosa
Why SSRIs often don’t work well in this population
The science behind ketamine and how it affects brain plasticity
Why the EDEN study focuses on improving mood rather than weight
How depression can reduce hope and motivation in recovery
The difference between medical ketamine treatment and recreational ketamine use
How the study has been shaped by people with lived experience
Why new treatment approaches needed in the eating disorder field
If you're interested in taking part in the EDEN study, the team are currently recruiting participants! Please email
[email protected] to find out more!
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⚠️ Content Note: This episode includes discussion of eating disorders, depression, ketamine use and mental health treatment.. Please take care when listening.
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Sending positive beans your way, Han 💛