What if so-called “mystery illnesses” are not mysterious at all, but the result of multiple systems being overwhelmed at the same time?
In this episode of Made for Health, Dr. Aaron Hartman is joined by Dr. Christian Jenski to explore a growing category of conditions often labeled as “mystery illnesses.” While the symptoms may seem confusing or unrelated, these complex cases often share common underlying drivers such as chronic infections, mold exposure, environmental toxins, immune dysfunction, and nervous system dysregulation.
Together, they explain why many patients with chronic fatigue, brain fog, anxiety, digestive issues, or unexplained symptoms often fall through the cracks of conventional medicine. This conversation highlights the importance of clinical curiosity, whole-person thinking, and understanding the connections between body systems to uncover root causes and help patients finally move forward in their healing journey.
Key Topics Covered
Why “mystery illness” is often a systems problem, not a mystery
The role of chronic infections like Lyme, Epstein-Barr, and tick-borne illnesses
How environmental exposures such as mold and toxins contribute to chronic symptoms
Why conventional medicine struggles with complex, multi-system conditions
The concept of being the “specialty between specialties” in functional medicine
How nervous system symptoms like anxiety, brain fog, and fatigue can signal underlying immune dysfunction
Cardiovascular and autonomic symptoms including POTS, dizziness, and heart rhythm changes
Digestive symptoms such as bloating, constipation, diarrhea, and organ inflammation
The connection between immune activation, swollen lymph nodes, and chronic viral reactivation
How layered triggers (stress, infection, toxins) create a domino effect in chronic illness
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