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Flex Diet Podcast

Dr. Mike T Nelson
Flex Diet Podcast
Latest episode

398 episodes

  • Flex Diet Podcast

    How to Harness Leucine and EAA for Bigger Muscles and More — Daniel A. Traylor, Ph.D. — #392

    29/06/2026 | 1h 40 mins.
    Can you really build more muscle just by rethinking how you dose leucine and essential amino acids? Dr. Daniel A. Traylor, Ph.D. — co-founder and principal scientist of LEUVATE™ — reveals the science behind protein quality, muscle protein synthesis, and why older adults may need twice the protein dose to get the same results as younger people.

    We dig into mTORC1 signaling, sarcopenia, the 30g protein absorption myth, GLP-1 drug effects on muscle, and the clinical trial data behind LEUVATE™. If you care about muscle, longevity, or protein strategy, this one is loaded.

    Guest Bio

    Daniel A. Traylor, Ph.D. is an Assistant Professor of Health Sciences at DePaul University in Chicago and Owner, Co-Founder, and Principal Scientist of LEUVATE™. His research explores how protein quality, amino acids, and exercise interact to influence muscle adaptation, recovery, and physical function across the lifespan. He is the co-inventor of LEUVATE™ — a precision-engineered leucine-enriched nutritional formula validated across multiple peer-reviewed human clinical trials.

    Timestamps

    3:36 — Can you really only absorb 30g protein at once?

    9:16 — Sarcopenia: the muscle-loss crisis in aging

    16:01 — mTORC1 and what triggers muscle protein synthesis

    20:46 — Why older adults may need twice the protein dose

    30:26 — The origin story of LEUVATE™

    34:01 — Leucine: the master switch for MPS

    37:56 — How leucine acts as a dimmer on mTORC1

    53:21 — GLP-1 drugs, muscle loss, and amino acid needs

    1:06:36 — LEUVATE™ vs whey: MPS data and ongoing trials

    1:17:01 — How leucine-enriched EAAs signal differently in the gut

    1:27:11 — Protein spiking and supplement quality red flags

    Resources

    LEUVATE™

    Dr. Traylor email

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  • Flex Diet Podcast

    Flex Diet Cert Closes at Midnight Mon 6/22/2026 and Coaching Leverage — #391

    22/06/2026 | 12 mins.
    In this solo episode, Dr. Mike T. Nelson introduces the concept of coaching leverage—the idea that effective coaching means multiplying physiological impact by a client's realistic ability to change.

    Why sleep is a physiological powerhouse but a coaching nightmare

    The coaching leverage formula: physiology × psychology

    Why protein ranks #1 (score: 81) and sleep ranks #8 (score: 20)

    How to stop majoring in the minors with your clients

    The eight interventions inside the Flex Diet Certification

    Why following a proven system beats reinventing the wheel

    The Flex Diet Certification closes tonight (Monday, June 22, 2026) at midnight Pacific. Get details here.

    Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
  • Flex Diet Podcast

    Antibiotics, Gut Microbiome, and the Exercise Connection — Dr. Sara Campbell — #390

    19/06/2026 | 1h 10 mins.
    In this episode of the Flex Diet Podcast, I sit down with Dr. Sara Campbell, Ph.D., Associate Professor at Rutgers University, for a conversation about the bidirectional relationship between exercise and the gut microbiome.

    Dr. Sara Campbell returns to discuss her lab's cutting-edge research on the bidirectional relationship between exercise and the gut microbiome — including why consumer gut tests oversimplify a complex ecosystem, how antibiotics devastate exercise capacity in animal models, and why single-microbe probiotics miss the bigger picture of functional guilds. She also shares new findings on short-chain fatty acids, amino acid metabolomics after antibiotic treatment, and the emerging neuromuscular junction hypothesis.

    In this episode you'll learn:

    Why consumer gut microbiome tests are misleading and what functional guilds tell us instead

    How antibiotics devastate exercise capacity and the surprising metabolomic changes they cause

    The current evidence on probiotics for exercise performance and why single strains fall short

    What short-chain fatty acids do for gut health and exercise, and the emerging neuromuscular junction hypothesis

    Find Sara here:
    Rutgers Faculty Page

    Google Scholar: Sara Chelland Campbell

    ---

    The Flex Diet Podcast is brought to you by the Flex Diet Certification. Learn more at miketnelson.com

    Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
  • Flex Diet Podcast

    The Flex Diet Cert is OPEN and AI vs Coaching Solocast — #389

    16/06/2026 | 17 mins.
    In this solo episode, Dr. Mike T. Nelson dives into the intersection of AI and coaching. Using his quest to pick up the 175-pound Inch dumbbell as an example, he shows how AI struggles with niche topics where quality training data is scarce — and why that matters for fitness advice.

    Topics covered:

    Why AI gave terrible advice on training for the Inch dumbbell — and what that reveals about how AI sources information

    The protein-and-kidney-damage myth: when AI repeats bad science

    Where AI actually helps coaches: data analysis, blood work organization, backend tasks, and production workflows

    Why clients still want (and need) a real human coach — accountability, customization, and skin in the game

    Will people be compliant to a robot coach? Probably not

    The baseline is rising: why just writing training and nutrition programs isn't enough anymore

    Flex Diet Certification — now open through Monday, June 22nd, 2026 at midnight PST. Eight interventions (protein, fats, carbs, exercise, sleep, micronutrition, fasting, and more) built on coaching leverage and metabolic flexibility. Includes direct email access to Dr. Nelson for enrolled students.

    Enroll now: https://miket.me/fdc

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  • Flex Diet Podcast

    What Vinegar & Lifting Really Do To Your Gut — Dr. Emily Dow — #388

    08/06/2026 | 1h 18 mins.
    Dr. Emily Dow, PhD, RD, is a researcher and registered dietitian working at the intersection of nutrition, resistance training, and gut health.

    Does vinegar actually do anything for your gut or your blood sugar? Can you trust a $200 mail-in microbiome test? Emily built her dissertation around questions like these, and her honest answers are a lot more useful than the marketing.

    Expect to learn what a 12-week resistance-training-plus-vinegar protocol did (and didn't do) to gut permeability, why a null result in a healthy population is still worth your attention, what the research really says about vinegar and glucose control, why the peptide boom warrants a hard dose of skepticism, what direct-to-consumer gut testing genuinely can and can't tell you, the underrated role stress plays in GI symptoms, and why the best practitioners do both research and hands-on coaching — and much more.



    Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter

    Connect with Dr. Dow: Website: https://www.dremilydow.com Instagram: https://www.instagram.com/dremilydow

    Episodes you'll enjoy next: #127 — The Effect of Antibiotics on Muscle Mass & Cardiovascular Performance with Dr. Sara Campbell: https://flex-diet-podcast.simplecast.com/episodes/episode-127-the-effect-of-antibiotics-on-muscle-mass-aerobic-cardiovascular-performance-and-more-an-interview-with-dr-sara-campbell
     #222 — Nutrition, Supplements & Training with RD Sean Casey https://flex-diet-podcast.simplecast.com/episodes/episode-222-expert-insights-on-nutrition-supplements-and-training-with-registered-dietician-sean-casey

    Enjoying the show? Follow the Flex Diet Podcast in your podcast app so new episodes land automatically — it's the single best way to help others find it.

    Timeline 

    0:00 Intro

    02:29 Vinegar Research Origins 

    04:12 Study Design & Training Protocol

    07:42 Biodex Explained: Strength Testing 

    11:49 Research Tradeoffs & Null Results 

    14:49 Possible Mechanisms: Acetate 

    19:55 Glycemic Control & CGM Findings 

    22:21 Peptides: Hype and Risks 

    28:54 Microbiome & Performance Research

    30:47 Gut Testing Skepticism 

    36:23 Stress and GI Symptoms 

    39:22 PhD to RD Fast Track 

    41:04 RD Exam Reality Check 

    44:25 Scope of Practice Basics 

    45:56 Referral Networks That Work 

    49:29 Research vs. Coaching Gap 

    58:51 Clients Drive Better Questions 

    01:05:26 Why She Started Instagram 

    01:09:58 Social Media for Academia 

    01:13:18 Training Goals and Tattoos 

    01:15:45 Where to Follow & Wrap Up

     

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About Flex Diet Podcast
Dr. Mike T Nelson gets geeky with the latest research and scientific findings in the fitness world. Visit www.flexdiet.com to get Flex Diet Certified and www.miketnelson.com for more geeky goodness.
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