The Egg Whisperer Show

I am so excited to share this conversation with you. In this episode, I sit down with Dr. Mark Ratner, Chief Science Officer at Theralogix, to talk about a topic I've become incredibly passionate about: NAD+ and its role in egg quality and fertility. If you've been wondering what NAD+ actually is, why your eggs need it, and whether supplementation could make a real difference in your IVF or egg freezing outcomes, this is a must-listen.
We get into the science of how NAD+ and sirtuins work together in our cells, why their decline with age is such a big deal for egg health, and the emerging research — from mouse studies to a promising new human trial — suggesting that boosting NAD+ levels could improve fertilization and pregnancy rates. I also share a personal story about a patient whose results completely blew me away after she started NAD+ supplementation on her own. This is the kind of conversation that gets me fired up about the future of fertility medicine.
In this episode, we cover:
What NAD+ is and how it's present in every cell of your body
The role of mitochondria in egg development and why eggs require more energy than any other cell
What sirtuins are and how SIRT1 appears to regulate ovarian reserve
How the age-related decline in NAD+ and sirtuins creates a "double whammy" for egg quality
The connection between NAD+, chromosomal abnormalities (aneuploidy), and diminished ovarian reserve
Key findings from mouse studies and a new human study showing doubled fertilization and clinical pregnancy rates with NAD+ boosting
How to start supplementing and what to look for
Resources:
Theralogix website: theralogix.com — Use discount code EGG for ~15% off
The IVF Class at The Egg Whisperer School 
The Egg Whisperer Show podcast on Spotify and Apple Podcasts Dr. Aimee's Supplement Stack information
Subscribe to my YouTube channel for more fertility tips!

Join Egg Whisperer School

Subscribe to the newsletter to get updates

Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

In this episode, I sit down with Dr. Ramy Ghayda, an experienced urologist and the Chief Medical Officer at Legacy, to dive deep into the world of male fertility. Dr. Ghayda brings his expertise in urology and male infertility to discuss why it's "always nice to have sperm on ice,"a phrase I say often because preserving male fertility is just as important as egg freezing. We explore Legacy's revolutionary approach to men's reproductive health, a digital fertility clinic that provides everything from at-home semen analysis and sperm freezing to DNA fragmentation testing, telehealth consultations, and nutritional support: all designed to fill the gap in fertility care that has traditionally focused only on women.


Throughout our conversation, Dr. Ghayda and I discuss the alarming decline in male fertility rates over the past few decades and what's causing it; from environmental toxins and endocrine-disrupting chemicals to lifestyle factors like diet, stress, and sleep. We talk about why fertility should be considered the sixth vital sign and how infertile men face higher risks of chronic diseases later in life. Dr. Ghayda also shares his passion for breaking the taboos around male infertility, rebalancing the emotional workload in couples struggling to conceive, and helping men understand that they are 50% of the fertility equation. This episode is a must-listen for anyone interested in optimizing their reproductive health or supporting their partner through the fertility journey.


In this episode, we cover:

Legacy's comprehensive approach to male fertility, including at-home semen analysis, sperm freezing, DNA fragmentation testing, and telehealth support
The science behind declining sperm counts and quality over the past 50 years and what environmental factors may be contributing
How lifestyle choices (smoking, alcohol, marijuana, heat exposure, diet, exercise, and sleep) directly impact sperm production
Why DNA fragmentation testing matters and how it can reveal correctable fertility problems
The emotional toll of infertility on men and how to rebalance the conversation and workload between partners
Why fertility is now being considered the sixth vital sign and its connection to overall health and longevity
Practical steps men can take to be proactive about their reproductive health and support their partners
Resources:

Legacy's website: https://www.givelegacy.com
Legacy's educational guides and resources on male fertility
The Egg Whisperer Show podcast on Spotify and Apple Podcasts
Dr. Aimee's Supplement Stack information
Subscribe to my YouTube channel for more fertility tips!

Join Egg Whisperer School

Subscribe to the newsletter to get updates

Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Keywords: male infertility, sperm freezing, sperm banking, Legacy fertility, Dr. Ramy Ghayda, semen analysis, DNA fragmentation test, declining sperm count, male fertility decline, environmental toxins, endocrine disrupting chemicals, lifestyle and fertility, testicular health, sperm quality, at-home fertility testing, digital fertility clinic, couples fertility journey, men's reproductive health, sperm motility, sperm concentration, andrology, urologist male fertility specialist, male factor infertility

Does sperm really matter? If you tuned into the conversation with Dr. Paul Turek and I earlier this week, you'll know that of course it matters!
 
It truly does take both sperm and an egg to make a baby. Today I'll review the sperm question a bit, and explain why it matters. AND, I'll give you a lot more info about how to improve sperm quality.
 
Here's the thing: I know that guys want to hear what they want to hear. They have selective listening. I'm not kidding when I tell you that I had someone email me recently and say "My husband's sperm tested out GREAT, and when we went over the results with the doctor we heard two different things. He thinks he heard our doctor say that it means he can just keep drinking, smoking, and enjoying marijuana and doesn't need to make any lifestyle changes. I heard something very different, which was that he should still cut back until we are pregnant. Can you help settle this for us?"
 
And while it's an unpopular answer (at least with the guys), my response is: Men should cut back or abstain from drinking, and smoking (marijuana too) if you're TTC.
 
Here are a few of the things I suggest to anyone bringing the sperm side of the equation to the baby making situation:
- consider freezing your own sperm for future use when you are young.
- get in the best shape of your life if you're trying to conceive. Sperm matters, and men's health is directly related to their sperm quality.
- take some prenatal vitamins. Yes, really. Many of the same supplements that I recommend for egg quality also are great for sperm quality.
- cut back on smoking, drinking, and drug use. Marijuana negatively impacts sperm.
- don't cook your balls: avoid hot tubs, using your laptop on your lap, and other situations that may create high temps for the area.
- find ways to cut back on stress, if you live a stressful life. Mindfulness and meditation are great for everyone.

Read the full transcript and article about this at my website.

Do you have questions about IVF?
Click here to join Dr. Aimee for The IVF Class.
The next live class call is on Monday, April 20th, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.

Click to find The Egg Whisperer Show podcast on your favorite podcasting app.
 
Watch videos of Dr. Aimee answer Ask the Egg Whisperer Questions on YouTube.
 
Sign up for The Egg Whisperer newsletter to get updates
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

On today's podcast episode, I'm joined by Dr. Kristin Bendikson and Dr. Dana McQueen, and we're discussing lifestyle factors and miscarriage. This discussion is part of a series on miscarriage and recurrent pregnancy loss (RPL). 
 
Dr. Dana McQueen is with RMA in San Francisco, and Dr. Bendikson is the director of clinical development at KindBody. She joins the show to talk about the life style factors that may come into play with miscarriage. We talk about BMI and body size, exercise, supplement, stress, and more.

Find out more on Dr. Aimee's website.

Visit Dr. Kristin Bendikson's website.

You can find Dr. Dana McQueen at RMA
 
Do you have questions about IVF, and what to expect?
Click here to join Dr. Aimee for The IVF Class.
The next live class call is on Monday, April 20, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.
 
Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org  where you can schedule a consultation.

Preparing for IVF can be an emotional and complex journey, and having the right information beforehand can make all the difference. In this episode, I'm joined by Dr. Max Ezzati, a highly respected reproductive endocrinologist, to discuss the most important thing to know before starting IVF.


Dr. Ezzati shares key insights about how patients can optimize their chances of success, the factors that influence embryo quality, and why understanding ovarian reserve is crucial. We also dive into the role of lifestyle factors, genetic screening, and cutting-edge advancements in reproductive medicine. If you're considering IVF or supporting someone on their fertility journey, this conversation will empower you with the knowledge you need.


One important concept we discuss is the IVF pyramid, which illustrates how the number of eggs retrieved translates to the number of viable embryos. Not every egg leads to a healthy embryo, and understanding this process can help patients set realistic expectations about their IVF journey.


In this episode, we cover:

How to assess your ovarian reserve before IVF
Why embryo quality matters and how it's evaluated
The importance of individualized treatment plans
How lifestyle factors, such as diet and stress, impact IVF outcomes
The role of genetic screening in IVF success
Common misconceptions about IVF and what patients should really focus on
Read the full show notes on my website.

Find Dr. Max Ezzati here.

Do you have questions about IVF? Click here to join me for The IVF Class. The next live class call is on Monday, April 20, 2026, at 4pm PST, where I'll explain IVF and Egg Freezing, and there will be time to ask your questions live on Zoom.


Other ways to reach me:
Visit my YouTube channel for more fertility tips!


Subscribe to the newsletter to get updates.


Join Egg Whisperer School.


Request a Consultation with me.


Dr. Aimee Eyvazzadeh is one of America's most well-known fertility doctors. Her success rate at baby-making gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.