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The Root Cause Medicine Podcast

Rupa Health
The Root Cause Medicine Podcast
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  • Modern Eye Care: The Gut-Eye Axis, Oculomics, HRT & More
    This episode features Dr. Neda Gioia, OD, CNS®, IFMCP, a pioneer in integrative eye care who blends optometry, clinical nutrition, and functional medicine to advance preventive vision strategies. Clinicians will learn how gut-eye axis mechanisms, AI-driven oculomics, sex-hormone transitions, and nutrient patterns influence ocular inflammation, retinal biomarkers, and whole-system health. Dr. Gioia illustrates how modern imaging (including emerging AI models), stool and hormone testing, and nutrient evaluation can support earlier identification of risk patterns and more personalized, prevention-forward care for patients across the lifespan.
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    56:15
  • Prescribing Joy: A Clinical Perspective with Cynthia Libert, M.D.
    In this inspiring episode of the Root Cause Medicine Podcast, Dr. Kate Kresge welcomes Dr. Cynthia Libert, a board-certified family physician, functional medicine expert, and creator of The Joy Prescription. Together they explore the biochemistry of joy, how gratitude reshapes brain connectivity, and how positive emotion can help to modulate inflammation, support neuroplasticity, and protect cognitive health. Clinicians will learn practical ways to integrate “joy prescriptions” into patient care, using evidence-informed tools to foster resilience and prevent burnout.
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    48:53
  • New Course: Advanced Blood Labs 201
    In this episode of The Root Cause Medicine Podcast, Dr. Kate Kresge interviews Dr. Chris Magryta and Dr. Erik Lundquist about Advanced Blood Labs 201—a course designed to help clinicians interpret metabolic and immune biomarkers across pediatric and adult populations. They explain how to use tests like C-peptide, adiponectin, leptin, and glutathione to identify early metabolic stress, and explore immune indices such as SII (Systemic Immune Inflammation Index) and SIRI (Systemic Inflammation Response Index) to uncover inflammation trends in both children and adults.
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    52:12
  • Breakthrough Evidence for Lithium in Alzheimer’s and Mental Health Treatment
    James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.
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    56:20
  • New Era for Osteoporosis Treatment: CTX, P1NP & Beyond
    James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.
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    1:14:20

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About The Root Cause Medicine Podcast

In each episode, we’ll meet renowned medical experts, specialists and pioneers who’ve influenced the way certain conditions and diseases are understood and treated. We focus on giving you the information you need to understand the root cause, symptoms and treatments available for specific medical conditions.
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