In this episode of The Root Cause Medicine Podcast, Dr. Kate Kresge interviews Dr. Chris Magryta and Dr. Erik Lundquist about Advanced Blood Labs 201—a course designed to help clinicians interpret metabolic and immune biomarkers across pediatric and adult populations. They explain how to use tests like C-peptide, adiponectin, leptin, and glutathione to identify early metabolic stress, and explore immune indices such as SII (Systemic Immune Inflammation Index) and SIRI (Systemic Inflammation Response Index) to uncover inflammation trends in both children and adults.
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52:39
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52:39
Breakthrough Evidence for Lithium in Alzheimer’s and Mental Health Treatment
James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.
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56:20
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56:20
New Era for Osteoporosis Treatment: CTX, P1NP & Beyond
James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.
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1:14:20
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1:14:20
Metabolic Flexibility: A Fullscript Forward Preview
True longevity requires metabolic flexibility, but how can we help our clients get there?
This episode previews personalized metabolic health and longevity strategies from Dr. Rob Downey and Monique Class, presenters at Fullscript Forward 2025. Dr. Downey discusses how metabolic phenotyping, stress/HRV context, and GI patterns can inform evaluation, while Monique describes low-dose (microdosed) GLP-1 approaches, titration by response, and gradual tapering within lifestyle-first care model help them achieve impactful results for their clients. The conversation explores objective monitoring (labs, body composition), muscle-preserving movement, and structured workflows that may help patients sustain progress after medication changes. This episode is for informational and educational purposes only.
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50:19
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50:19
Breaking Down the New GLP-1 Advisory with Lara Zakaria, IFMCP
This episode of The Root Cause Medicine Podcast explores how the 2025 GLP-1 prescribing advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society can act as a catalyst for whole-person metabolic care—rather than just symptom management. Lara Zakaria, IFMCP, pharmacist and functional medicine practitioner, breaks down the new consensus guidelines and highlights opportunities to integrate nutrition counseling, strength training, and lab monitoring to support muscle preservation, nutrient adequacy, and patient safety. You’ll hear Lara’s practical approach—starting with screening for eating disorders and nutrient status before prescribing—and learn how to design workflows that make guideline implementation realistic in busy clinical settings. Providers will leave with evidence-informed strategies to improve patient outcomes, minimize side effects, and support sustainable behavior change around GLP-1 therapy.
In each episode, we’ll meet renowned medical experts, specialists and pioneers who’ve influenced the way certain conditions and diseases are understood and treated. We focus on giving you the information you need to understand the root cause, symptoms and treatments available for specific medical conditions.
Ireland