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The Root Cause Medicine Podcast

Rupa Health
The Root Cause Medicine Podcast
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  • Unexplained Infertility: 6 Factors to Investigate with Dr. Jessica Christie
    In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge is joined by Dr. Jessica Christie, a licensed naturopathic doctor, clinical nutritionist, and integrative fertility expert, to discuss a diagnosis that frustrates both patients and practitioners: unexplained infertility. Dr. Christie explains that “unexplained” can sometimes mean “we haven’t found the root cause yet,” and she walks us through six of the most common hidden causes of fertility struggles—from subclinical hypothyroidism and nutrient deficiencies to autoimmune markers and environmental toxin exposure. Whether you’re a patient searching for answers or a practitioner looking for a more complete workup, this conversation offers evidence-based strategies, powerful case examples, and a hopeful message: unexplained doesn’t mean unsolvable. You’ll hear them discuss: - Why “unexplained infertility” is a diagnosis of exclusion—and what it often misses (Abdallah et al., 2020) - Six common, often-overlooked root-cause contributors to fertility struggles - How research links subclinical hypothyroidism with IVF success rates (Cho et al., 2015) - The immune markers linked to miscarriage and implantation failure (Demir et al., 2009; Shahbazi et al., 2019; Sauer et al., 2010; Jalilvand et al., 2023; Edassery et al., 2010) - Why gut and vaginal dysbiosis matter for egg quality and implantation (Patel et al., 2022; Tersigni et al., 2014; Blancafort & Llácer, 2023) - The micronutrients most essential for fertility—and most commonly deficient (Skoracka et al., 2021; Ji et al., 2023) - How to approach detoxing safely when trying to conceive (Jain & Singh, 2022; Pizzorno, 2017; NCCIH, 2019) - Real patient stories that show what’s possible with root-cause medicine
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  • Essential Pediatric Health Tips Every Parent Needs to Know with Dr. Elisa Song Part 2: Episode Rerun
    In today's episode of The Root Cause Medicine Podcast, we're gonna go over what to do when your kid gets sick, including what to do, what not to do, and how you can address the top 25 acute childhood concerns using an integrative approach with Dr. Elisa Song. You’ll hear us discuss: 1. Integrative approaches to pediatric health 2. Post-antibiotic recovery for your kids 3. Engaging your vagus nerve to enhance your health 4. Breathing exercises for children 5. Homeopathy and natural remedies for children's health Dr. Elisa Song is a holistic pediatrician and pediatric functional medicine expert who has helped over 1,000 children thrive by combining conventional pediatrics with functional medicine, homeopathy, essential oils, and Traditional Chinese Medicine. She is the Founder of Healthy Kids Happy Kids, a trusted online resource for holistic pediatric advice. Dr. Song is also the Founder and Holistic Pediatrician at Whole Family Wellness. Her new book, Healthy Kids, Happy Kids: An Integrative Pediatrician’s Guide to Whole Child Resilience, offers practical insights on how to nurture resilient children. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide
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  • The Truth About Supplement Safety with Dr. Eric Viegas
    In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with Dr. Eric Viegas, a naturopathic doctor and Fullscript’s Medical Product Manager, to pull back the curtain on the world of supplement quality and safety. From raw ingredient sourcing to manufacturing audits, Dr. Viegas explains what CGMP really means, how Fullscript ensures product integrity, and why certifications like NSF and third-party testing matter. You’ll learn how to evaluate your supplements for quality, what common industry terms really mean (or don’t), and what to avoid—like potentially dangerous sports nutrition products and under-tested trendy gummies. Whether you’re a clinician or a supplement-savvy consumer, this episode offers practical insights to help you navigate the supplement landscape with confidence. You’ll hear them discuss: - What CGMP certification actually means—and why it matters - The hidden dangers of poor manufacturing practices and counterfeit products - Why Fullscript’s catalog is CGMP-certified across all 375+ brands - How and why supplements like turmeric are tested for purity, potency, and contamination - The surprising problems with gummies and “pharmaceutical grade” claims - Which third-party certifications actually mean something (and which don’t) - Why the supplement industry is regulated—but not in the way most people assume - How Fullscript handles recalls, audits, and adverse event reports - What every provider and consumer should know before recommending or taking a supplement
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  • Hard Case? Start Here. Functional Immunology for Complex Cases with Dr. Sam Yanuck
    In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with functional immunology expert and educator Dr. Samuel Yanuck to explore one of the most overlooked systems in chronic illness: the immune system. With clarity and compassion, Dr. Yanuck breaks down how immune dysregulation can contribute to complex conditions like depression, neuropathy, migraines, chronic fatigue, and even cardiovascular disease. From brain inflammation and mast cell activation to Epstein-Barr virus and mold, Dr. Yanuck offers a new way of thinking about biology—where inflammation isn’t just a symptom, but a system that can be measured, understood, and treated. You’ll here them discuss: - Why immunology could be at the root of nearly every chronic illness - The immune pathways that connect depression, anxiety, brain fog, and fatigue - What PANS, PANDAS, and autoimmune encephalitis really are—and why they’re often misdiagnosed - How gut, brain, and immune health form a feedback loop - The labs you should run if you suspect chronic immune dysfunction - A framework for evaluating chronic viral infections like EBV and CMV - Natural immune modulators: Chinese skullcap, astragalus, quercetin, sulforaphane, and more - Why personalized immune workups—not protocols—create results Guest Bio: Dr. Samuel Yanuck is a functional medicine clinician and expert educator in functional immunology. He is the creator of Cogence Immunology, a comprehensive online training program that has educated over 9,000 clinicians in over 60 countries. His approach blends immunology, clinical experience, and systems thinking to help providers and patients uncover the true drivers of chronic illness. Dr. Yanuck is also the co-founder of the Yanuck Center for Life and Health in North Carolina, where he sees patients and helps clinicians find root-cause solutions to immune dysfunction through mentorship and collaboration. His work is helping reshape how the next generation of practitioners understand inflammation, autoimmunity, and healing. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide
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  • The Ageless Brain: Dr. Dale Bredesen on Preventing Cognitive Decline
    In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with neurologist and bestselling author Dr. Dale Bredesen to challenge everything we think we know about brain aging. Dr. Bredesen shares why age-related cognitive decline is not just treatable but in many cases preventable—and even reversible. Drawing on decades of lab research and clinical success, he outlines the root causes of cognitive decline and introduces the listener to the "cognoscopy," a powerful tool for early detection. With practical, science-backed insights on inflammation, insulin resistance, environmental toxins, and the emerging brain microbiome, this is a masterclass in 21st-century brain health. You’ll here them discuss: - Why cognitive decline is often preventable—and sometimes reversible - The three key drivers of cognitive decline: inflammation, energy deficit, and toxicity - How to use the "cognoscopy" to catch signs of dementia early - The role of the brain’s microbiome and oral health in neurodegeneration - Why mold, metals, and mycotoxins are underestimated threats - New blood biomarkers like pTau217, GFAP, and NFL - Supplements that support brain health, including magnesium threonate and omega-3s - How to tailor treatment using functional lab testing and wearables - Stories of patient recovery—and what makes the difference Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide
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About The Root Cause Medicine Podcast

In each episode, we’ll meet renowned medical experts, specialists and pioneers who’ve influenced the way certain conditions and diseases are understood and treated. We focus on giving you the information you need to understand the root cause, symptoms and treatments available for specific medical conditions.
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