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The a16z Show

Andreessen Horowitz
The a16z Show
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1016 episodes

  • The a16z Show

    Ben Horowitz and Balaji Srinivasan on Netscape and Network States

    28/1/2026 | 42 mins.
    Can a country be built from the internet up? Not as a metaphor or an online community, but as a system that replaces institutions we usually think of as fixed, money, law, and governance.
    In this conversation taken from The Network State Podcast, a16z cofounder Ben Horowitz joins Balaji Srinivasan to explore how internet native institutions are beginning to mirror and challenge traditional state structures. Drawing parallels to China’s early special economic zones, they discuss how constrained experiments like Shenzhen tested new rules without rewriting the entire system, and why similar experimentation is now happening online.
    The discussion examines crypto, digital identity, and network states as attempts to turn code into coordination and coordination into legitimacy, while grappling with a core tension. Code is deterministic, but societies are not. Ben and Balaji explore where these systems work, where they break, and whether network states are a curiosity or the next phase of governance.
     
    Resources:
    Follow Ben on X: https://x.com/bhorowitz
    Follow Balaji on X: https://x.com/balajis
    Listen to more from The Network State: https://ns.com/podcast
     
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    Find a16z on X: https://x.com/a16z
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    https://www.linkedin.com/company/a16z
    Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX
    Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711
    Follow our host: https://x.com/eriktorenberg](https://x.com/eriktorenberg
    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see http://a16z.com/disclosures.
     
     
     

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

    27/1/2026 | 1h 34 mins.
    Out-of-Pocket is a healthcare education company founded by Nikhil Krishnan that helps people understand how healthcare works and how to navigate it in practice. In this episode, a16z investing partner Jay Rughani and Nikhil discuss why health insurance is losing its role as the default way people access care. They explain how rising costs are pushing more consumers to pay out of pocket for diagnostics, preventive care, and navigation. The conversation also looks at what this shift means for startups, AI-powered tools, regulation, and access as healthcare continues to move beyond insurance.
    Resources:
    Follow Jay Rughani on X:  https://twitter.com/JayRughani
    Follow Nikhil Krishnan on X: https://twitter.com/nikillinit
    Read Out of Pocket’s 2026 Predictions: https://www.outofpocket.health/p/out-of-pockets-2026-predictions
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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
     

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    The Hidden Economics Powering AI

    26/1/2026 | 1h 4 mins.
    In this episode, Jen Kha, Head of Investor Relations, and David George, General Partner, discuss how late-stage private markets are evolving as AI reshapes scale, capital intensity, and growth timelines. They explain why AI-driven companies are staying private longer, how infrastructure spending is changing return profiles, and what this moment means for durability, value creation, and long-term outcomes in private markets.
    Timecodes:
    0:00 — Introduction
    04:21 — The Market Opportunity for AI
    26:48 — Pricing, Monetization, and Cash Burn
    43:15 — Companies Staying Private Longer
    51:30 — Portfolio Composition and Construction
    57:18 — Team Culture and Collaboration
     
    Resources:
    Follow Jen Kha on X: https://x.com/jkhamehl
    Follow David George on X: https://x.com/DavidGeorge83
     
    Stay Updated:
    If you enjoyed this episode, be sure to like, subscribe, and share with your friends!
    Find a16z on X: https://x.com/a16z
    Find a16z on LinkedIn: https://www.linkedin.com/company/a16z
    Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX
    Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711
    Follow our host: https://x.com/eriktorenberg
    Not an offer or solicitation. None of the information herein should be taken as investment advice; Some of the companies mentioned are portfolio companies of a16z. Please see https://a16z.com/disclosures/ for more information.  A list of investments made by a16z is available at https://a16z.com/portfolio.

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    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    How Mintlify Is Rebuilding Documentation for Coding Agents

    23/1/2026 | 44 mins.
    Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li and Yoko Li speak with Han and Hahnbee about how coding agents are changing what “good docs” mean, shifting documentation from a human-only resource into infrastructure that powers AI tools, support agents, and internal knowledge workflows. They share Mintlify’s early journey, including eight pivots, the two-day prototype that landed their first customer, and the “do things that don’t scale” sales motion that helped them win early traction. The conversation also covers why docs go out of date, what “self-healing” documentation requires to actually work, and how serving fast-moving customers has shaped both their product priorities and their pace.
    Follow Jennifer Li on X: https://twitter.com/JenniferHli
    Follow Yoko Li on X: https://twitter.com/stuffyokodraws
    Follow Han Wang on X: https://twitter.com/handotdev
    Follow Hahnbee Lee on X: https://twitter.com/hahnbeelee

    Stay Updated:
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    Listen to the a16z Show on Spotify
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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    Inferact: Building the Infrastructure That Runs Modern AI

    22/1/2026 | 43 mins.
    Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, cheaper, and more reliable to run across any hardware, model architecture, or deployment environment. Together, they broke down how modern AI models are actually run in production, why “inference” has quietly become one of the hardest problems in AI infrastructure, and how the open-source project vLLM emerged to solve it. The conversation also looked at why the vLLM team started Inferact and their vision for a universal inference layer that can run any model, on any chip, efficiently.
    Follow Matt Bornstein on X: https://twitter.com/BornsteinMatt
    Follow Simon Mo on X: https://twitter.com/simon_mo_
    Follow Woosuk Kwon on X: https://twitter.com/woosuk_k
    Follow vLLM on X: https://twitter.com/vllm_project

    Stay Updated:
    Find a16z on X
    Find a16z on LinkedIn
    Listen to the a16z Show on Spotify
    Listen to the a16z Show on Apple Podcasts
    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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About The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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