Want to Automate your work with AI? Get the playbook here: https://clickhubspot.com/wgk
Episode 66: Can you really build a zero-employee business with AI? Nathan Lands (https://x.com/NathanLands) sits down with John Rush (https://x.com/johnrushx), founder and self-proclaimed builder of “the most automated org on earth,” to unpack what it takes to launch and run a company where 80% of the work (and soon, 100%) is done by AI agents.
John shares his journey from managing large VC-backed teams to going fully solo and using AI to automate nearly every task in his startups, from prototyping and front-end design to sales outreach and SEO content creation. The conversation covers unique agent workflows, how to rapidly test business ideas, how specialized vs. generalist AI agents can supercharge productivity, and practical insights for solopreneurs and founders curious about leveraging automation for scale.
Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd
—
Show Notes:
(00:00) Transitioning from Teamwork to AI Entrepreneurship
(04:01) Rapid AI Prototyping Strategy
(08:40) Specialized vs. General AI Agents
(10:25) Automating Marketing with Limited Coding
(13:38) Embrace AI Agents' Autonomy
(19:09) AI Directories Enhance Contextual Accuracy
(22:36) LLMs Prefer Directories Over Blog Posts
(23:31) LLMs and Directory Discovery
(28:36) Reddit Manipulation Exploits Google's Search Algorithm
(30:42) Elon Musk Boosts X Account
(34:36) AI Progress Hindered by Infrastructure Constraints
(39:11) Limit Screen Time for Balance
(42:11) Leveraging AI for Business Innovation
(43:07) Weekly Idea Generation Strategy
—
Mentions:
John Rush: https://www.linkedin.com/in/johnrushx/
Unicorn Platform: https://unicornplatform.com/
Grok: https://x.ai/
Replit: https://replit.com/
Cursor: https://cursor.com/en
Lindy: https://www.lindy.ai/
Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw
—
Check Out Matt’s Stuff:
• Future Tools - https://futuretools.beehiiv.com/
• Blog - https://www.mattwolfe.com/
• YouTube- https://www.youtube.com/@mreflow
—
Check Out Nathan's Stuff:
Newsletter: https://news.lore.com/
Blog - https://lore.com/
The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano
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47:00
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47:00
What's Actually Coming in AI (From Someone Building It)
Episode 65: What’s actually coming next in AI, and how will it transform the fundamental infrastructure we rely on every day? Matt Wolfe (https://x.com/mreflow) sits down with DJ Sampath (https://x.com/djsampath), Senior Vice President of AI Products at Cisco, for a deep dive into the AI-powered future of networking, security, and the enterprise.
In this episode, DJ Sampath—former CEO and founder of Armorblox, now leading Cisco’s AI product division—shares an exclusive look at Cisco’s new AI Canvas platform: a generative UI that enables seamless collaboration between humans and AI agents for real-time, intelligent problem solving. Matt and DJ pull back the curtain on how Cisco is modernizing the internet’s backbone, why the enterprise is ground zero for AI-enabled transformation, and the critical new challenges of AI security as agents multiply by the billions. If you want to understand what’s really next in enterprise AI—and how it connects to your own experience as a consumer—don’t miss this fascinating, forward-looking conversation.
Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd
—
Show Notes:
(00:00) AI Innovations with Cisco's DJ Sampath
(06:06) Enterprises Adopting AI Revolution
(09:09) Integrated Cisco Product Connectivity
(11:08) AI Surprises: Creativity Unleashed
(14:57) Embrace AI for Job Security
(16:36) AI Revolutionizes Research Efficiency
—
Mentions:
Want 17 pages of Matt's favorite AI Tools? Get it here: https://clickhubspot.com/vwo
DJ Sampath: https://www.linkedin.com/in/djsampath/
Cisco: https://www.cisco.com/
Armorblox: https://www.cisco.com/site/us/en/products/security/secure-email/armorblox/index.html
AI Canvas: https://newsroom.cisco.com/c/r/newsroom/en/us/a/y2025/m06/announcing-cisco-ai-canvas-revolutionizing-it-with-agenticops.html
—
Check Out Matt’s Stuff:
• Future Tools - https://futuretools.beehiiv.com/
• Blog - https://www.mattwolfe.com/
• YouTube- https://www.youtube.com/@mreflow
—
Check Out Nathan's Stuff:
Newsletter: https://news.lore.com/
Blog - https://lore.com/
The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano
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22:16
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22:16
12 INSANE AI Agent Use Cases in Lindy AI (Live Demo)
Episode 64: What if you could hire an AI intern to handle your meetings, emails, CRM, and even negotiate refunds over the phone? Nathan Lands (https://x.com/NathanLands) is joined by Flo Crivello (https://x.com/Altimor), founder of Lindy AI, a leading AI agent platform in Silicon Valley.
In this episode, Flo gives a revealing look into how Lindy’s AI agents are already replacing entire teams in startups by automating sales outreach, executive assistance, scheduling, meeting notes, CRM, recruiting, and even handling live phone calls and negotiations. Watch live demos, discover the smartest use cases, see how AI agents collaborate, and learn how you can start leveraging these capabilities in your own business. Plus, Flo opens up about where work and productivity are headed as AI interns get smarter and more independent.
Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd
—
Show Notes:
(00:00) AI As Versatile Digital Interns
(06:04) Calendar Management Preferences
(07:34) Automated Meeting Summary Prompt
(11:36) AI-Driven Decision Workflow
(13:15) AI Filters Sponsorship Emails
(18:02) AI Memory and Meeting Transcription
(20:43) Use Examples for Better Prompts
(25:07) AI Conversations: A Unique Era
(26:57) Flight Canceled, Unexpected Refund
(30:00) Friday Phone Check-Ins with Elon Lindy
(34:15) Deepfakes Overblown, Future of Work
(37:51) The Unknowable Future Beyond Singularity
(38:29) Post-Work Utopia vs. Tech-Dystopia
—
Mentions:
Want the ultimate guide on AI Agents? Get it here: https://clickhubspot.com/efh
Flo Crivello: https://www.linkedin.com/in/florentcrivello/
Lindy: https://www.lindy.ai/
Claude: https://claude.ai/
Greg Isenberg’s interview with Flo: https://podcasts.apple.com/mx/podcast/i-built-a-team-of-ai-agents-that-grow-my-business-24-7-full-demo/id1593424985?i=1000703493519
Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw
—
Check Out Matt’s Stuff:
• Future Tools - https://futuretools.beehiiv.com/
• Blog - https://www.mattwolfe.com/
• YouTube- https://www.youtube.com/@mreflow
—
Check Out Nathan's Stuff:
Newsletter: https://news.lore.com/
Blog - https://lore.com/
The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano
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43:04
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43:04
Turn Your Idea Into a Working App With One Prompt (Live Demo)
Episode 63: What if you could turn your idea into a fully working app—just by describing it in plain English? Matt Wolfe (https://x.com/mreflow) sits down with Anton Osika (https://x.com/antonosika), CEO of Lovable, a revolutionary platform that lets anyone build and launch software using AI—no code or development team required.
In this episode, Anton gives a live demo of Lovable, reveals how creators of all ages—including kids and solo founders—are launching real businesses in hours, and dives into how AI-powered platforms like Lovable will change the future of entrepreneurship, creativity, and even move us closer to AGI. If you’re a builder, maker, or curious about the next frontier in software creation, this conversation will reshape how you think about launching your next product.
Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd
—
Show Notes:
(00:00) AI-Powered Code Revolution
(04:21) Engineers as Problem Translators
(07:50) Supabase Integration Simplifies Startups
(10:49) Enhancing Design and Collaboration
(16:46) Intuitive AI Interface Development
(19:31) AI Empowering Solo Entrepreneurs
(22:40) Future of Software Development: Automation Impact
(24:18) Lovable App
—
Mentions:
Want better prompts? Get our guide to Advanced Prompt Engineering: https://clickhubspot.com/wbo
Anton Osika: https://www.linkedin.com/in/antonosika/
Lovable: https://lovable.dev/
Supabase: https://supabase.com/
Claude: https://claude.ai/
Gemini: https://gemini.google.com/
Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw
—
Check Out Matt’s Stuff:
• Future Tools - https://futuretools.beehiiv.com/
• Blog - https://www.mattwolfe.com/
• YouTube- https://www.youtube.com/@mreflow
—
Check Out Nathan's Stuff:
Newsletter: https://news.lore.com/
Blog - https://lore.com/
The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano
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28:48
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28:48
Can AI Help You Live to 170?
Episode 62: Could an AI that knows everything about your health help you live to an extreme age? Nathan Lands (https://x.com/NathanLands) sits down with Max Marchione (https://x.com/maxmarchione), founder of Superpower, to explore the future of AI-powered longevity.
In this episode, Nathan and Max dive deep into how artificial intelligence is transforming the field of medicine—making personal health tracking, diagnostics, and preventative care more accessible than ever. Max explains why he believes everyone will soon have an AI doctor more knowledgeable than any human, how Superpower integrates wearables and biomarker data into actionable protocols, and why supplements might be overrated, even if he still takes dozens each day. If you want to live longer, thrive in the age of AI, and get practical longevity tips, you won’t want to miss this conversation.
Check out The Next Wave YouTube Channel if you want to see Matt and Nathan on screen: https://lnk.to/thenextwavepd
—
Show Notes:
(00:00) AI Doctors are the Future
(05:44) Comprehensive Health Data Analysis
(08:04) Closing Healthcare Gaps with AI
(11:58) Technology's Role in Medical Knowledge
(12:40) Preferring Doctors Over AI
(16:56) Supplements: Not All Beneficial?
(19:30) Trial Data Gathering Sleep Devices
(24:23) Impending Cyborg Reality
(25:28) Focus on People, Not Skills
(28:21) Discovering Real-World Potential
—
Mentions:
Want Matt's favorite AI Tools? Get it here: https://clickhubspot.com/klw
Max Marchione: https://www.maxmarchione.com/
superpower: https://superpower.com/
Bryan Johnson: https://blueprint.bryanjohnson.com/
ChatGPT: https://chatgpt.com/
Get the guide to build your own Custom GPT: https://clickhubspot.com/tnw
—
Check Out Matt’s Stuff:
• Future Tools - https://futuretools.beehiiv.com/
• Blog - https://www.mattwolfe.com/
• YouTube- https://www.youtube.com/@mreflow
—
Check Out Nathan's Stuff:
Newsletter: https://news.lore.com/
Blog - https://lore.com/
The Next Wave is a HubSpot Original Podcast // Brought to you by Hubspot Media // Production by Darren Clarke // Editing by Ezra Bakker Trupiano
About The Next Wave - AI and The Future of Technology
The Next Wave is your personal Chief AI Officer, bringing fresh takes, industry insights and a trustworthy perspective on how to implement AI to grow your business.
Join Matt Wolfe and Nathan Lands, as they democratize the expertise often reserved for the boardrooms of the biggest corporations. From groundbreaking technologies to practical applications, Matt and Nathan will cover everything you need to stay informed and prepared. Whether you're seeking to adapt your company to the AI era or simply curious about the future, this podcast will equip you with the knowledge to thrive in the forthcoming wave of change.
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