LONGEVITY with Nathalie Niddam

Today, I'm joined by Dr. Grace Liu, often known as the “Gut Goddess,” a trailblazer in the world of microbiome science and founder of The Gut Institute. In this conversation, we take a bold dive into an often-overlooked pillar of longevity: your poop. That's right—Dr. Liu unpacks the fascinating and sometimes surprising science showing how gut health shapes everything from your immune system and brain to your lifespan itself.

Episode Timestamps:

Introduction to host ... 00:00:00

Dr. Grace Liu on the gut as a hallmark of aging ... 00:04:06

Peptides, FMT, and evidence for gut-driven regeneration ... 00:05:04

FMT safety, immune education, and the environmental “microdosing” effect ... 00:07:07

Links between gut aging, the immune system, and mental health ... 00:08:13

Diet, ancestry, and resistant starch for butyrate production ... 00:15:01

Ancestral diet, microbiome differences, and pitfalls of shortcuts ... 00:18:53

Fiber, polyphenols, and the key longevity bacteria ... 00:24:09

Gut markers, loss of diversity, and ABC species signature ... 00:25:15

Risks of overhyped probiotics, strep, and broad interventions ... 00:36:29

Peptides, bioregulators, and repairing the gut ... 01:12:01

Practical longevity: movement, daily habits & where to learn more ... 01:22:46

Our Amazing Sponsors:

Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. 

O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.

CP1 Pure Collagen Peptides by Puori — a clean, unflavored collagen that supports connective tissue, joints, and skin elasticity with a unique amino acid profile your body actually uses, plus full third-party testing; go to puori.com/NAT and use code NAT for 32% off when you start a subscription.

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Dr. Bill Lawrence Episode

Today, I'm joined by the insightful Dr. Meenal Agarwal, an eye doctor and passionate advocate for reimagining how we think about vision and brain health. In our conversation, Dr. Agarwal reveals the surprising ways our daily screen habits are shaping not just our eyesight, but also our emotional regulation, cognitive performance, and even the development of anxiety and ADHD-like symptoms. She opens up about her own journey—from an unexpected period of cognitive "off-ness" during a stint away from her clinical work, to pioneering a powerful perspective on "spatial awareness processing disorder."
 
Episode Timestamps:
Introduction and Episode Overview ... 00:00:00
Impact of Vision on Brain and Longevity ... 00:00:37
Sponsors: Gut and Toxin Health ... 00:01:07
Eye-Brain Connection Fundamentals ... 00:04:30
Peripheral Vision, Screens, and Anxiety ... 00:08:06
Case Study: Childhood Myopia and Screens ... 00:20:37
Prevention: Breaks and the 20-20-20 Rule ... 00:25:30
Recognizing and Addressing Spatial Processing Issues ... 00:27:25
Annual Eye Exams and Early Detection ... 01:09:40
Nutrition and Biohacks for Eye-Brain Health ... 01:17:13
Advice for Parents and Screen Balance ... 01:14:08
Book Insights and Closing ... 01:24:28
Where to Find Dr. Agarwal ... 01:26:45
 
Our Amazing Sponsors:
Ultimate GI Repair by LVLUP Health — a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off
 
Micro-BOOST (Humic Mineral Complex) by BEAM Minerals - A concentrated liquid humic formula that binds and removes toxins like heavy metals, mold, and pollutants—working fast with just a daily shot. Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order. 
 
Vita Zero-Age Exosomes by Vitali Skincare — a regenerative "stacking" formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the amazing Melissa Urban, the force behind Whole30 and a global champion of accessible nutrition. In our conversation, Melissa opens up about a surprising discovery in her wellness journey: sleep, not just food, is often the real foundation of long-term health. She shares how overlooked sleep hijacked her cravings, impacted her insulin sensitivity, and even chipped away at her resilience—revealing the invisible costs that only show up years down the line.
 
Visit ozlosleep.com/nat and use code NAT to get $95 off
 
Episode Timestamps:
Welcome and podcast introduction ... 00:00:00
Poor sleep's impact on cravings and insulin ... 00:00:47
Melissa Urban's wake-up calls: burnout and disrupted sleep ... 00:00:59
Tech sleep hack: Ozlo noise-canceling earbuds ... 00:01:06
Sleep's effect on diet and insulin sensitivity ... 00:06:42
Cravings, mood, and resilience with sleep loss ... 00:08:49
Melissa Urban's sleep disruption stories: motherhood, book tour, menopause ... 00:10:02
Sleep and technology: SleepBuds saving marriage ... 00:12:42
Sleep consistency as key for resilience and health ... 00:17:47
Chronic light sleep: cognitive and metabolic consequences ... 00:20:09
Hormonal disruption and menopause sleep challenges ... 00:24:42
Sleep refresh tips: environment and habits ... 00:26:07
Screen-free wind-down routines ... 00:27:41
Midlife sleep wisdom: earlier bedtime ... 00:34:37
Physical and mental benefits of good sleep ... 00:36:06
Noise canceling vs. masking: SleepBuds explained ... 00:39:18
Sleep supplements: magnesium, melatonin, CBD ... 00:48:28
One impactful habit: eliminate screens and alcohol ... 00:53:30
Where to find Melissa Urban and Ozlo ... 00:56:27
 
Our Amazing Sponsors:
Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD™ to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10
 
MassZymes by BiOptimizers – A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat—try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT.
 
Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience—visit timeline.com/NAT to get 20% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by David Roberts and Dr. John Gildea, two passionate researchers whose work sits at the cutting edge of environmental health and longevity science. In this episode, we dive deep into the catalyst for developing a stabilized sulforaphane supplement—something born out of both necessity and relentless curiosity. David opens up about how environmental toxicity stopped being theoretical for him, and Dr. Gildea brings a wealth of clinical insight into why supporting our detox pathways could be a game-changer for chronic disease prevention.

Offer: Get 25% off stabilized sulforaphane products for a limited time at mara-labs.com/NAT with code NAT (offer ends April 7th 2026; 15% off thereafter).
 
Episode Timestamps:
Welcome and podcast intro ... 00:00:00
When toxins became personal: cancer & environment ... 00:04:54
Practical detox: household and lifestyle changes ... 00:06:12
Sulforaphane's effect on inflammation and daily function ...00:07:07
Finding health solutions outside conventional medicine ... 00:14:44
Cancer diagnosis prompts sulforaphane stabilization ... 00:18:17
NRF2: master regulator in aging, skin, and detox ... 00:24:16
Sulforaphane, curcumin, and inflammation ... 00:25:11
Supplement confusion: sulforaphane vs. glucoraphanin ... 00:31:10
Food as medicine and practical dosing ... 00:34:51
Microplastics: exposure, health risks, and impacts ... 00:35:31
Detox routes and microplastics research ... 00:47:04
Glyphosate, NRF2 suppression, and gut barriers ... 00:52:54
Sulforaphane boosts detox and protects against pollution ... 00:59:13
GLP-1s, muscle loss risk, and supplement alternatives ... 01:00:08
Berberine: sleep, glucose, and microbiome effects ... 01:06:12
Synergies, future research, and sulforaphane limits ... 01:10:32
Sprouts, seeds, and potency of broccoli compounds ... 01:16:17
 
Our Amazing Sponsors:
Vitali SkinCare - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.
 
Tro Zzz by Troscriptions – a fast-acting, customizable sleep formula designed to quiet racing thoughts and support deeper, more restorative sleep using a powerful blend of GABA-supporting compounds, cannabinoids, and sleep-promoting ingredients. Head to troscriptions.com, use code NAT10, and get 10% off.
 
Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After the wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries—from cancer concerns to menopause, sourcing, and practical tips.
Click Here for list of BIOREGULATOR NAMES
 
Books mentioned in this episode:
The Peptide Bioregulator Revolution (Great primer on bioregulators)
Author: Dr. Marios Kyriazis
Peptides and the Epigenetic Control of Aging  (Technical, science-heavy)
Author: PhD Vladimir Khavinson, MD, PharmaB Phil Micans, MS, PhD Alexander Maryanovich, MD 
 
Episode Timestamps:
Welcome and sponsor introduction ... 00:00:00
Autophagy and Primadene ... 00:00:44
Bioregulator basics and liver support ... 00:01:58
Cancer and telomere lengthening peptides ... 00:05:56
Bioregulators and cancer: caution advised ... 00:08:06
Immune bioregulators and cancer recovery ... 00:12:31
Book reference: "Peptide Bioregulator Revolution" ... 00:13:54
Bioregulators for immune support ... 00:14:44
When not to use bioregulators ... 00:16:56
Menopause, ovarian aging, and bioregulators ... 00:17:47
Clinical outcomes in women ... 00:23:57
GLP-1s and bioregulator absorption ... 00:27:01
Preventative strategies by age ... 00:28:57
Epitalon safety and dosing ... 00:33:18
Bioregulator sourcing and access ... 00:35:41
Amazon caution for supplements ... 00:38:01
Emerging science and trusted brands ... 00:40:03
Social media challenges and newsletter ... 00:44:30
 
Our Amazing Sponsors:
Primeadine by Oxford Healthspan — A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout.
 
Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.   http://www.profound-health.com/?Aff=Longevity15
 
O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.
 
Nat's Links: 
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Dr. Bill Lawrence Episode