LONGEVITY with Nathalie Niddam

Today, I’m sitting down with the trailblazing Dr. Tyna Moore, a pioneer in reframing the conversation around GLP-1 medications. Instead of focusing solely on weight loss, Dr. Moore reveals how these powerful molecules can open a critical window to reset our health story—if we’re willing to harness that opportunity wisely.
Episode Timestamps:
Welcome, host introduction, and overview ... 00:00:00
Stigma, marketing, and confusion around GLP-1 use ... 00:05:38
True microdosing vs. standard dosing explained ... 00:08:18
Strength training as essential during GLP-1 therapy ... 00:12:06
GLP-1 medications as windows of opportunity for health resets ... 00:13:24
Risks of extreme thinness and frailty for longevity ... 00:15:11
Why metabolic health matters at every age ... 00:20:56
PCOS renamed as a metabolic disease ... 00:26:07
Senescence, exercise, and aging ... 00:28:10
Dr. Tyna Moore’s GLP-1 research and patient findings ... 00:30:34
GLP-1s reveal deeper metabolic issues ... 00:37:28
Differentiating semaglutide, tirzepatide, retatrutide ... 00:39:41
Liver fat, lean mass loss, and weight regain challenges ... 00:43:59
Personalized dosing, side effects, and patient variability ... 00:46:53
Digestive health, SIBO, and supporting GLP-1 users ... 00:52:37
Lab monitoring and practical implementation ... 01:01:04
Immune impacts, senescence, and metabolic improvements ... 01:02:29
Lifestyle first: exercise, peptide stacking, and fundamentals ... 01:10:49
Cautious optimism for the future of GLP-1s ... 01:12:08
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Dr. Bill Lawrence Episode

Today, I’m joined by Zack Abbott, a biotech innovator who took an unconventional path—from pharmaceutical science to the front lines of consumer health. Instead of following the well-worn route of drug development, Zack set his sights on bringing cutting-edge biotechnology directly to people, creating products designed not just for convenience, but for genuinely transforming our relationship with microbiology.

Anyone who uses code NATNIDDAM will get 10% off their first order! Visit https://zbiotics.com/NATNIDDAM.

Episode Timestamps:

Podcast introduction and host background ... 00:00:00

Consumer impact versus traditional drug industry ... 00:06:06

Gap and opportunity for biotech in consumer space ... 00:06:42

Engineered probiotics: not hacks but new relationships with biology ... 00:07:19

Scientific and public responses to engineered probiotics ... 00:09:03

Technology behind genetically engineered probiotics explained ... 00:17:39

Bacillus subtilis: why it’s the ideal delivery vehicle ... 00:27:08

Sugar-to-fiber product mechanism and rationale ... 00:32:58

Importance of fiber quantity and diversity for gut health ... 00:42:26

Sugar-to-fiber: capabilities and limitations ... 00:54:06

Keto/carnivore implications and who benefits from sugar-to-fiber ... 00:57:51

Misunderstandings and realities about GMOs in consumer biotech ... 01:00:02

Regulation, safety, and honest claims in biotech supplements ... 01:07:01

Current science and future of the microbiome in longevity ... 01:12:14

Personalization, AI, and microbiome-directed health ... 01:13:10

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Dr. Bill Lawrence Episode

Today, I’m joined by Dr. Robin Rose, a double board-certified gastroenterologist and internal medicine physician who has become a true pioneer in the space of functional and precision medicine. Driven by a relentless curiosity that survived even the most rigid medical training, Dr. Rose shares how her quest to answer “why” led her beyond conventional medicine into root-cause healing, patient-centered care, and the world of gut health, biochemistry, and the microbiome.

Episode Timestamps:

Show introduction and host background ... 00:00:00

Early skepticism of conventional GI protocols ... 00:04:30

Embracing probiotics, nutrition, and functional medicine ... 00:05:26

Medical education’s gaps in microbiome and nutrition ... 00:06:12

Critique of diagnosis-driven, algorithmic medicine ... 00:09:39

Leaving conventional practice for holistic, systems biology ... 00:10:12

The body as an interconnected ecosystem ... 00:15:31

Microbiome, mitochondria, immune interplay ... 00:17:53

Chronic illness and the failure of “one size fits all” protocols ... 00:19:26

Gut-brain-immune axis and its health implications ... 00:22:09

Gut-driven neurodegeneration, mood, and immunity ... 00:24:07

Long Covid: definitions and persistence ... 00:29:29

Spike protein’s toxic role in long Covid and aging ... 00:30:27

Viral, vaccine, and bacterial factors in ongoing disease ... 00:33:04

Diagnostics, individualized protocols, and new treatments ...00:44:54

Prevention and recovery: gut, spike, and diet strategies ... 00:52:52

Daily recommendations and practical steps for longevity ... 01:02:07

Quick-fire gut health myths and personal insights ... 01:07:45

Where to find Dr. Robin Rose and episode wrap-up ... 01:10:09

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Dr. Bill Lawrence Episode

Today, I’m joined by Dr. Andrew Salzman, a pioneer in NAD research whose work has spanned everything from pediatric sepsis to cutting-edge longevity science. Dr. Salzman dives deep into why NAD isn’t just another supplement buzzword, but a central molecule powering our energy, resilience, and even fertility.

Wonderfeel is gifting a 7-day Youngr™ supply with every Youngr™ order. Click here and use code NAT at checkout to claim your complimentary gift. Offer ends two weeks from today’s episode.

Episode Timestamps:

Introduction ... 00:00:00

Scientific rigor in supplement development ... 00:06:49

Evolution of medicine and the role of populist health ... 00:09:37

Changing views on aging and longevity ... 00:14:13

NAD’s role in energy, repair, and aging ... 00:17:22

When NAD starts to decline and why it matters ... 00:21:06

Early signs of NAD deficiency ... 00:22:22

NAD’s connection to fertility and reproductive health ... 00:25:03

Gut health, inflammation, and NAD depletion ... 00:34:16

Lifestyle and diet drivers of NAD loss ... 00:39:35

How to assess NAD needs ... 00:42:11

Boosting NAD: supplement strategies and limits ... 00:44:09

NMN versus NR and dosing ... 00:46:05

Wonderfeel’s approach: address depletion and boost levels ... 00:51:53

Commonly reported results and user feedback ... 00:54:52

Creatine’s critical role in cellular energy and aging ... 00:57:55

Future directions: criticism, biomarkers, and personalization ... 01:10:10

Podcast wrap-up, offers, and disclaimer ... 01:15:09

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Dr. Bill Lawrence Episode

Today, I’m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle—and uncovered what so many thyroid patients are missing.
Episode Timestamps:
Welcome and episode introduction ... 00:00:00
Thyroid care gaps and Hashimoto’s paradigm shift ... 00:07:05
Understanding Hashimoto’s and why levothyroxine often falls short ... 00:08:24
Comprehensive thyroid testing and antibody significance ... 00:14:34
Hashimoto’s as an autoimmune gateway and risk escalation ... 00:16:00
The five root causes of Hashimoto’s ... 00:17:15
Chronic infections, spike protein, and immune activation ... 00:21:21
Food’s impact: diet strategy and common dietary pitfalls ... 00:27:01
A three-step framework to reverse Hashimoto’s ... 00:43:44
Practical challenges, especially stress management ... 00:48:00
Peptides and bioregulators: clinical use and observations ... 00:50:09
GLP-1 agonists: thyroid risks and benefits ... 00:58:36
Transformative patient story ... 01:00:48
Thyroid’s centrality to longevity and early testing advice ... 01:03:33
Family support and final resources ... 01:10:09
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Bioregulators by Nature’s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order.
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Dr. Bill Lawrence Episode