LONGEVITY with Nathalie Niddam

Today, I’m joined by Zack Abbott, a biotech innovator who took an unconventional path—from pharmaceutical science to the front lines of consumer health. Instead of following the well-worn route of drug development, Zack set his sights on bringing cutting-edge biotechnology directly to people, creating products designed not just for convenience, but for genuinely transforming our relationship with microbiology.

Anyone who uses code NATNIDDAM will get 10% off their first order! Visit https://zbiotics.com/NATNIDDAM.

Episode Timestamps:

Podcast introduction and host background ... 00:00:00

Consumer impact versus traditional drug industry ... 00:06:06

Gap and opportunity for biotech in consumer space ... 00:06:42

Engineered probiotics: not hacks but new relationships with biology ... 00:07:19

Scientific and public responses to engineered probiotics ... 00:09:03

Technology behind genetically engineered probiotics explained ... 00:17:39

Bacillus subtilis: why it’s the ideal delivery vehicle ... 00:27:08

Sugar-to-fiber product mechanism and rationale ... 00:32:58

Importance of fiber quantity and diversity for gut health ... 00:42:26

Sugar-to-fiber: capabilities and limitations ... 00:54:06

Keto/carnivore implications and who benefits from sugar-to-fiber ... 00:57:51

Misunderstandings and realities about GMOs in consumer biotech ... 01:00:02

Regulation, safety, and honest claims in biotech supplements ... 01:07:01

Current science and future of the microbiome in longevity ... 01:12:14

Personalization, AI, and microbiome-directed health ... 01:13:10

Our Amazing Sponsors:

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Ultimate GI Repair by LVLUP Health — a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 15% off

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Dr. Bill Lawrence Episode

Today, I’m joined by Dr. Robin Rose, a double board-certified gastroenterologist and internal medicine physician who has become a true pioneer in the space of functional and precision medicine. Driven by a relentless curiosity that survived even the most rigid medical training, Dr. Rose shares how her quest to answer “why” led her beyond conventional medicine into root-cause healing, patient-centered care, and the world of gut health, biochemistry, and the microbiome.

Episode Timestamps:

Show introduction and host background ... 00:00:00

Early skepticism of conventional GI protocols ... 00:04:30

Embracing probiotics, nutrition, and functional medicine ... 00:05:26

Medical education’s gaps in microbiome and nutrition ... 00:06:12

Critique of diagnosis-driven, algorithmic medicine ... 00:09:39

Leaving conventional practice for holistic, systems biology ... 00:10:12

The body as an interconnected ecosystem ... 00:15:31

Microbiome, mitochondria, immune interplay ... 00:17:53

Chronic illness and the failure of “one size fits all” protocols ... 00:19:26

Gut-brain-immune axis and its health implications ... 00:22:09

Gut-driven neurodegeneration, mood, and immunity ... 00:24:07

Long Covid: definitions and persistence ... 00:29:29

Spike protein’s toxic role in long Covid and aging ... 00:30:27

Viral, vaccine, and bacterial factors in ongoing disease ... 00:33:04

Diagnostics, individualized protocols, and new treatments ...00:44:54

Prevention and recovery: gut, spike, and diet strategies ... 00:52:52

Daily recommendations and practical steps for longevity ... 01:02:07

Quick-fire gut health myths and personal insights ... 01:07:45

Where to find Dr. Robin Rose and episode wrap-up ... 01:10:09

Our Amazing Sponsors:

Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience—visit timeline.com/nat20 to get 20% off.

Apollo Neuro — A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/NAT and use code NAT for $99 off and 1 year Smart Vibes Ai.

Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Click HERE and use code NAT10

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Dr. Bill Lawrence Episode

Today, I’m joined by Dr. Andrew Salzman, a pioneer in NAD research whose work has spanned everything from pediatric sepsis to cutting-edge longevity science. Dr. Salzman dives deep into why NAD isn’t just another supplement buzzword, but a central molecule powering our energy, resilience, and even fertility.

Wonderfeel is gifting a 7-day Youngr™ supply with every Youngr™ order. Click here and use code NAT at checkout to claim your complimentary gift. Offer ends two weeks from today’s episode.

Episode Timestamps:

Introduction ... 00:00:00

Scientific rigor in supplement development ... 00:06:49

Evolution of medicine and the role of populist health ... 00:09:37

Changing views on aging and longevity ... 00:14:13

NAD’s role in energy, repair, and aging ... 00:17:22

When NAD starts to decline and why it matters ... 00:21:06

Early signs of NAD deficiency ... 00:22:22

NAD’s connection to fertility and reproductive health ... 00:25:03

Gut health, inflammation, and NAD depletion ... 00:34:16

Lifestyle and diet drivers of NAD loss ... 00:39:35

How to assess NAD needs ... 00:42:11

Boosting NAD: supplement strategies and limits ... 00:44:09

NMN versus NR and dosing ... 00:46:05

Wonderfeel’s approach: address depletion and boost levels ... 00:51:53

Commonly reported results and user feedback ... 00:54:52

Creatine’s critical role in cellular energy and aging ... 00:57:55

Future directions: criticism, biomarkers, and personalization ... 01:10:10

Podcast wrap-up, offers, and disclaimer ... 01:15:09

Our Amazing Sponsors:

Quantum Upgrade – A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at QuantumUpgrade.io and use code NAT15.

Micro-BOOST (Humic Mineral Complex) by BEAM Minerals - A concentrated liquid humic formula that binds and removes toxins like heavy metals, mold, and pollutants—working fast with just a daily shot. Head to http://www.beamminerals.com/NAT20, use code NAT20, and get 20% off your first order.

Daily Gut Detox by Just Thrive Health – A gentle, science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion—without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free.

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Dr. Bill Lawrence Episode

Today, I’m joined by the inspiring Dr. Anshul Gupta, a conventionally trained family physician who completely reimagined thyroid care after his own life and health hit a breaking point. Dr. Gupta shares how his battle with fatigue, weight gain, and relentless gut pain led him down a path beyond prescriptions, ultimately transforming his personal health and medical practice. Through functional medicine, he found a way out of his own struggle—and uncovered what so many thyroid patients are missing.
Episode Timestamps:
Welcome and episode introduction ... 00:00:00
Thyroid care gaps and Hashimoto’s paradigm shift ... 00:07:05
Understanding Hashimoto’s and why levothyroxine often falls short ... 00:08:24
Comprehensive thyroid testing and antibody significance ... 00:14:34
Hashimoto’s as an autoimmune gateway and risk escalation ... 00:16:00
The five root causes of Hashimoto’s ... 00:17:15
Chronic infections, spike protein, and immune activation ... 00:21:21
Food’s impact: diet strategy and common dietary pitfalls ... 00:27:01
A three-step framework to reverse Hashimoto’s ... 00:43:44
Practical challenges, especially stress management ... 00:48:00
Peptides and bioregulators: clinical use and observations ... 00:50:09
GLP-1 agonists: thyroid risks and benefits ... 00:58:36
Transformative patient story ... 01:00:48
Thyroid’s centrality to longevity and early testing advice ... 01:03:33
Family support and final resources ... 01:10:09
Our Amazing Sponsors:
Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Give it a try at troscriptions.com/NATPODCAST or enter NATPODCAST at checkout for 10% off your first order.
O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.
Bioregulators by Nature’s Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order.
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Dr. Bill Lawrence Episode

Today, I’m joined by the incredibly insightful Donna Jackson Nakazawa, a science journalist and bestselling author whose work bridges the worlds of neuroscience, storytelling, and personal transformation. Donna has a unique gift for translating complex brain science into real-life strategies—and she’s not afraid to weave in her own powerful journey, from childhood trauma and autoimmune challenges to her fierce quest for hope and healing.
Episode Timestamps:
Podcast introduction and episode overview ... 00:00:00
Chronic stress, childhood adversity, and lifelong health ... 00:07:04
Microglia as the link between stress and brain changes ... 00:10:47
Protector vs destroyer: microglia’s dual role in the brain ... 00:11:21
Neuroplasticity and hope for healing at any age ... 00:15:19
Modern stressors and impacts on kids’ brain health ... 00:17:25
Safety, rumination, and reshaping the brain’s wiring ... 00:18:22
Donna’s personal journey with trauma and autoimmune illness ... 00:38:00
How to break rumination: the MIST framework ... 00:47:40
The science and power of language on health ... 01:01:00
Daily practice tips to disrupt negative thought cycles ... 01:07:26
Rethinking longevity: focus on healthspan and connection ... 01:10:03
How to preorder the book and connect online ... 01:11:38
Podcast outro and disclaimer ... 01:13:02
Our Amazing Sponsors:
Ultimate GI Repair by LVLUP Health — a research-backed blend of peptides, zinc carnosine, and gut-support compounds designed to strengthen your gut lining, improve digestion, and support resilience from the inside out; head to lvluphealth.com and use code NAT for 20% off
MassZymes by BiOptimizers – A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat—try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT.
Vita Zero-Age Exosomes by Vitali Skincare — a regenerative “stacking” formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off.
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Dr. Bill Lawrence Episode