#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)
Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:45)Improving VO2 Max and cardiovascular health (11:28)Blood tests and metabolic health (16:42)Hormone tests and longevity (21:35)Microbiome tests and toxicity (26:55)Microplastics and environmental toxicity (32:14)Food sensitivity testing (39:01)NAD testing and energy metabolism (41:50)Comprehensive health retreat (49:29)Dr. Joy Kong Youtube channel: https://www.siimland.co/retreat
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#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky
Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metabolism in 2001.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:25 What are mitochondria03:55 Mitochondria in aging and longevity06:00 Oxidative stress, inflammation, and longevity09:30 Antioxidants and benefits of exercise12:40 Bon Charge sponsorship13:30 Who should take antioxidants21:30 Mark’s antioxidant cocktail study24:30 Why is exercise the best thing for your mitochondria30:35 How endurance training shapes the mitochondria35:10 High intensity interval training36:50 Role of mitochondria in muscle loss42:00 Nutrition for mitochondrial health46:50 Supplements for mitochondrial health53:35 Stimulating mitophagy Dr Mark Tarnopolsky research page: https://scholar.google.com/citations?user=4jhi_KkAAAAJ&hl=en
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#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longevity14:33 Muscle building genetics19:33 FOXO3 and stress resilience24:53 FOXO3 gene editing32:08 Can telomere lengthening be harmful to some individuals38:58 IGF-1 and growth hormone and longevity50:08 Genetically short sleepers54:38 What you should know about your longevity genesFirst podcast with Tyler about genetics and supplements: https://youtu.be/9GLbTEYewUsTyler Panzner channel: https://www.youtube.com/@drtylerpanzner
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#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast
Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sleep, movement, diet, environment22:47 – Caution on rapamycin, metformin, methylene blue25:54 – FOXO3 stem-cell study and what it means37:15 – Mindset and willpower as real enhancers41:44 – TMG, astaxanthin, melatonin, creatine47:09 – VO2 max priorities and performance trade-offs48:51 – Balancing fitness with joy and purpose53:18 – Biomarkers mediate risk more than labels1:01:00 – 2030–2040: what is realistic1:04:02 – Immortality probabilities and living well nowJulian Issa video podcast: https://youtu.be/vV8yMVGLG6Y?si=XiLxOx0bSSM-xT-v
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#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more
Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Does exercise increase inflammation03:03 Melatonin megadosing research04:23 NOVOS vs Blueprint VS DoNotAge07:44 Hidden things that contribute to my health12:14 Bon Charge sponsorship13:05 How to improve night shift work15:40 Supplements to take before the sauna17:15 Does caffeine age the brain19:34 Can you make up for lost sleep20:40 Thoughts on Urolithin A23:14 Doing too much for longevity27:59 How to stop waking up at 3AM30:57 How much sodium do I consume33:20 Do sleep supplements blunt natural sleep37:07 Inflammation in longevity41:23 Importance of good relationship with food
Siim Land is an author, speaker, and consultant. He talks about optimizing health, performance, and longevity with different techniques and biohacking.
Ireland