
Series 2, Episode 30: Professor Ed Bullmore on Inflammation, Depression and the Immune Brain
16/12/2025 | 43 mins.
In this conversation, Professor Ed Bullmore discusses the intricate relationship between inflammation and mental health, particularly depression. He explains how inflammation can manifest in both physical and psychological symptoms, emphasizing the importance of understanding low-grade inflammation and its impact on mental well-being. The discussion also covers the significance of blood tests in identifying inflammation, the need for holistic treatment approaches, and the potential of alternative therapies. Professor Bullmore highlights the role of temperature extremes, the effects of menopause on mental health, and the biological differences in inflammation responses between genders. He concludes with insights into current research and future directions in the field of mental health.Depression can be linked to inflammation in the body and brain.Low-grade inflammation can affect mental health even without obvious disorders.Blood tests like CRP can indicate inflammation levels.Holistic approaches to treatment are necessary for better mental health outcomes.Alternative therapies like diet and exercise are gaining scientific credibility.Temperature extremes may have health benefits worth exploring.Menopause can increase the risk of mental health issues due to hormonal changes.There are biological differences in how men and women experience inflammation.Chronic stress can lead to immune dysregulation and affect mental health.Current research is focusing on the immune system's role in mental health.Author of The Inflamed Mind.

Series 2, Episode 29: Midlife, Hormones & Power: Dr. Mariza Snyder on Rewriting the Perimenopause Story
09/12/2025 | 56 mins.
In this powerful and deeply validating episode, I sit down with Dr. Mariza Snyder, bestselling author, hormone expert and leading voice in women’s midlife health, to unpack the reality of perimenopause and what every woman deserves to know about her hormones. Dr. Mariza shares how her work was inspired by watching her mother struggle through perimenopause with little support or guidance and how that experience ignited her mission to change the way women are educated and cared for during midlife. She explains why so many women begin experiencing symptoms in their late thirties and early forties and why these signs are so often overlooked, misdiagnosed or dismissed. She shares how to recognize early symptoms, why blood testing and biomarkers matter, and how personalized hormone support including hormone replacement therapy can be life changing when introduced at the right time. Dr. Mariza also speaks powerfully about the importance of women advocating for their own health and not accepting minimizing answers when they know something feels off. This conversation goes far beyond hormones. It is about reclaiming power in midlife, building supportive communities, and reframing this stage of life not as decline but as an opportunity for clarity, strength and confidence.• Why perimenopause often begins earlier than most women expect• The most common symptoms that are frequently dismissed• Why blood testing and biomarkers are essential for proper hormone care• When hormone replacement therapy can be most beneficial• How to advocate for yourself inside the medical system• The powerful role of community during midlife transitions• Why reframing aging is key to empowerment• How movement and lifestyle changes directly impact hormonal health• Dr. Mariza’s passion for women’s health began with her mother’s perimenopause journey• Many women experience the first signs of perimenopause in their late thirties and early forties• Recognizing symptoms early leads to better long term health outcomes• Blood testing is essential for understanding what is truly happening hormonally• Hormone replacement therapy can be incredibly supportive when started at the appropriate time• Women must learn to advocate for their health inside a system that often minimizes their symptoms• Community and shared experience make midlife transitions easier and less isolating• Empowerment and self care are essential during this phase of life• Movement and lifestyle shifts play a huge role in hormonal balance and overall wellbeing• Every woman deserves comprehensive informed and compassionate care throughout her health journeyThis episode is for women who feel off but cannot quite explain why, for those questioning whether their symptoms are stress burnout or hormones, for anyone curious about perimenopause and what is coming next, and for women ready to step into midlife with education power and confidence.Find Dr. Mariza at:https://drmariza.com/

Series 2, Episode 28: Dr. Lisa Koche on Unblocking the Flow: Emotional Healing as the Missing Link in Energy, Health, and Miracles
02/12/2025 | 37 mins.
This week on the Sweaty AF Podcast, I’m joined by the brilliant Dr. Lisa Koche, triple board-certified physician, functional medicine expert, and founder of Spectra Wellness.Dr. Lisa is known for her deeply integrative, root-cause approach to healing, blending conventional medicine, functional diagnostics, nervous system regulation, and emotional health to help people truly heal from the inside out.In this conversation, we explore how unresolved emotional patterns can silently cap our ability to heal, receive, and thrive. Lisa shares a powerful metaphor she uses with patients to illustrate how fear, unworthiness, and stored emotional stress can block the flow of energy, health, and possibility in our lives.We dive into why emotional healing is not separate from physical healing, but often the key that unlocks real transformation. From burnout and chronic fatigue to feeling stuck in life, this episode offers a new lens on what it really means to heal at the deepest level.Emotional blocks can limit our ability to heal and receiveFear and unworthiness often sit beneath physical symptomsRemoving emotional barriers allows energy and vitality to returnHealing must address both the body and the nervous systemPersonal growth is a core component of long-term wellnessTrue vitality requires emotional safety, not just protocolsExpansion happens when we allow ourselves to receiveYou can learn more about Dr. Lisa Koche and her work at:www.drlisakoche.com

Series 2, Episode 27: Longevity Starts in Your Cells: The Mitochondria Episode with MitoQ's CSO, Dr. Siobhan Mitchell
25/11/2025 | 47 mins.
In this episode of the Sweaty AF podcast, Dr. Siobhan Mitchell discusses the critical role of mitochondria in aging, health, and cognitive function. She explains how MitoQ, a supplement designed to target mitochondria, can help improve energy levels and potentially reverse some effects of aging. The conversation also covers the importance of NAD+ in cellular function, the impact of estrogen on women's health, and the future of mitochondrial research, particularly in relation to cognitive decline and mood disorders.Mitochondria are crucial for energy production and aging.Caloric restriction is the most effective method for longevity.Oxidative stress from ATP production can damage cells.Mitochondria play a role in various diseases of aging.MitoQ is designed to target and protect mitochondria.NAD+ levels decline with age, affecting energy and cognition.Estrogen influences mitochondrial function in women.PQQ can improve cognitive function and sleep quality.Stress and cortisol can negatively impact mitochondrial health.MitoQ shows promise in treating cognitive decline and mood disorders.For more info or to purchase go to:https://www.mitoq.com/For an extra 10% off use code SWEATYAF

Series 2, Episode 26: Rewiring the Brain: Neuroplasticity, Recovery, and the Power of the Rebound Method with Dr. Brody Miller
18/11/2025 | 31 mins.
In this episode of the Sweaty Air podcast, Dr. Brody Miller shares his transformative journey from experiencing a life-altering brain injury to becoming a leading expert in brain optimization and neuroplasticity. He discusses the techniques he used to rewire his brain, including meditation and the Rebound Method, which encompasses physical, emotional, and spiritual recovery. The conversation delves into the importance of nutrition, exercise, and emotional regulation for brain health, as well as emerging science in brain regeneration. Dr. Brody emphasizes the significance of consistency and small changes in achieving optimal brain function and longevity.takeawaysDr. Brody's journey began with a severe brain injury.Neuroplasticity allows the brain to rewire itself.Meditation can physically change the structure of the brain.The Rebound Method includes physical, emotional, and spiritual recovery.Nutrition plays a crucial role in brain health.Movement and exercise are essential for cognitive performance.Emotional regulation is a vital skill in today's world.Breath work can enhance stress tolerance and emotional regulation.Engaging in practical brain exercises can improve cognitive function.Emerging science shows promise in brain regeneration techniques.Find Dr. Brody here:https://drbrodymiller.com/https://www.instagram.com/drbrodymiller/



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