Derms on Drugs

• What If Every Day Was a Bad Hair Day?

  Admit it—bad hair days are the worst. Now imagine every day is one. Alopecia’s psychological impact is way deeper (and more surprising) than most people think. This week, the Derms on Drugs sit down with Harvard’s Dr. Maryanne Makredes Senna to unpack the mental side of AA—and then dive into what to do when a JAK inhibitor just… doesn’t JAK. As always, we’re answering the questions you didn’t even know you had.Here’s what we’re tackling:What hits harder on anxiety and depression—scarring or non-scarring alopecia?How tightly does AA severity track with psychological burden?How should you approach the mental health effects of AA?(Yes, you should ask. No, you shouldn’t be the one treating—here’s how to bridge patients to the right therapists.)And what do you do when a JAK Inhibitor isn’t giving you the results you hoped for?

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• Boosting Isotretinoin, Outsmarting Botox Resistance & Other Plot Twists

  This week, the Derms on Drugs are back with another literature speed-run—think 3D chess meets derm nerd nirvana. We’re answering questions you didn’t even know you had (and a few you wish you didn’t).Here’s what we’re tackling:Do herbal supplements turn up dermatomyositis?Can biologics cut down on blood clots in HS?Wait… does Claritin supercharge isotretinoin?Is Sotyktu stirring up rosacea?How good is the new oral IL-23 inhibitor icotrokinra for psoriasis?Any fresh weapons against demodex?Anything new for those stubborn pemphigus oral lesions?What to do when your patient is resistant to multiple botulinum toxins?And—holy grail alert—can we actually prevent chemo-induced alopecia in breast cancer?

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• The Best Central Centrifugal Scarring Alopecia Discussion You've Ever Heard

  The Derms on Drugs are joined by Dr. Crystal Aguh from Johns Hopkins for an AMAZING discussion on central centrifugal scarring alopecia.  From uber practical, cheap, safe, effective treatment approaches to deep science on what is happening in this disease, listen this week and you'll be an expert - how to talk to these patients, the baseline treatments everybody should be on, when to get more aggressive, when to step therapy back - the whole enchilada.  We even throw in a little frontal fibrosing alopecia.  Quite honestly one of the best episodes we've ever done.  The Derms on Drugs learned new approaches to this disease and we promise, you will too!

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• From Blood Vessels to Mighty Mites: What’s Hot (and maybe not) in Dermatology Right Now

  Join us this week as the Derms on Drugs crew discusses the latest in the Dermatology literature.  Topics for this episode include: - Cutaneous vasculitis of the skin (it’s a Chapel Hill thing)- Ozempic face, butt, and body- TAC injections for AA – what concentration do you use?- Does the MERLIN study deserve its magical name?- Are systemic JAK inhibitors the answer for vitiligo?- And everyone’s favorite – Demodex mites!

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• Pediatric Psoriasis

  You don't see a lot of kids with psoriasis, but when you do it can be a big challenge, especially if it's bad and they need a systemic.  The Derms on Drugs are coming to the rescue!  We'll have a special guest - Dr. Doug Kress (who was heavily involved in training all three of the Derms on Drugs) who has enormous experience treating pediatric psoriasis.  We'll get into all the stuff you really need to know:-What systemic drugs are approved for psoriasis under the age of 18?-What does the data say about which ones work the best?-How good is Tremfya, the first IL-23 inhibitor approved in kids, and where will it fit?-How is psoriasis in kids different from psoriasis in adults?-What are the roles of the different topicals approved for psoriasis in kids?-How do we think about therapy selection differently in kids vs adults?-Do kids get psoriatic arthritis?-What about shots vs pills in kids?-How do you talk to parents about the different biologics for kids?-How do you handle vaccines in kids who are psoriasis biologics?-Do you ever use methotrexate in kids?

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