Fat Science

• The People Side of Metabolic Medicine

  In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the human connections in metabolic medicine. With special guest Alisha, a nurse practitioner at the Cooper Center for Metabolism, the episode delves into how patient-provider relationships have a profound impact on metabolic health outcomes. If you're interested in how the world of metabolic medicine is evolving and want a human-centered perspective, this episode is a must-listen. You’ll walk away with a better understanding of how interconnected our body’s health systems are and why personalized care matters.Key Takeaways:Alisha’s Journey: Discover how Alisha transitioned from the ICU to preventive care in metabolic medicine, driven by her desire to prevent end-stage diseases she witnessed firsthand.Breaking Myths: The episode sheds light on why counting calories isn't the answer and how metabolic dysfunction is not just a collection of isolated symptoms but a comprehensive system affecting overall health.Preventive Mindset: Learn from Dr. Cooper and Alisha as they discuss the importance of early intervention, preventive care, and how understanding your body’s metabolic signals today can avert future health issues.Finding the Right Help: Looking for an expert in obesity medicine? Click the following link to find a board-certified specialist in your area: https://abom.learningbuilder.com/public/membersearchResources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, send an email to [email protected].  If you have a show idea, feedback, or just want to connect, you can also reach us us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  35:37
• Listener Spotlight

  On this episode of Fat Science, it’s time to hear from some of you, our listeners. Dr. Emily Cooper, Andrea Taylor and Mark Wright are joined by two loyal listeners, Scott and Heidi. The episode explores personal anecdotes and transformative moments thanks to a deeper understanding of metabolic health and its broader implications. It also shows you don’t have to have Metabolic Syndrome to benefit from understanding the science connected to it.Key Takeaways:Weight control and diets have long been struggles, but a scientific understanding of metabolism can demystify these challenges.Addressing familial and individual metabolic issues requires comprehensive evaluation beyond lifestyle adjustments.Sleep quality profoundly affects metabolic rates, highlighting the interplay between hormones like ghrelin and leptin.Personal Stories & Practical Advice:Scott finds resonance with the podcast through its unpacking of metabolism beyond diet culture, while Heidi recognizes the alleviation of stress and restriction, changing family health dynamics.Dr. Cooper pushes for awareness of underlying medical issues over lifestyle blame, advocating for thorough evaluations.Resources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, send an email to [email protected].  If you have a show idea, feedback, or just want to connect, you can also reach us us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  37:52
• Compounded Drugs Part 2

  On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright delve deeper into the topic of compounded metabolic drugs. Dr. Cooper addresses criticisms from listeners about the previous discussion and provides insights into the economic reasons driving people towards compounded drugs. She also dissects the ethics and economics of the diet industry transforming into a subscription medicine model and the role of insurance in accessibility to metabolic treatments.Key Takeaways:Compounded drugs often act as a misleading alternative to brand medications, lacking FDA approval and potentially jeopardizing health outcomes.Employers significantly influence weight-related treatment coverage, and advocacy for coverage changes can be a crucial step towards accessible medications.Insurance restrictions and economic barriers force many to explore compounded drugs despite potential risks.The rise of online subscription models parallels the diet industry’s modus operandi of exploiting vulnerable demographics for profit.Greater transparency and regulation within the pharmaceutical and insurance sectors are needed to ensure safe and equitable access to treatments.Personal Stories & Practical Advice:Andrea reflects on her decision to prioritize health despite the significant cost by sourcing medications through Canada rather than risking compounded drugs.Discussions emphasize the importance of a comprehensive and guided medical approach, advocating for patient education and active engagement with healthcare providers.Important Update: Changes in GLP-1 Medication Availability and Compounding RegulationsThis episode was recorded before recent regulatory developments regarding GLP-1 medications. As of our current information:The FDA has determined that shortages have been resolved for all formulations of tirzepatide (marketed as Mounjaro and Zepbound) and semaglutide (marketed as Rybelsus, Ozempic, and Wegovy). Consequently, compounding these medications is no longer legally permitted under FDA regulations.Additionally, Novo Nordisk has expanded its patient assistance program by implementing enhanced coupon discounts across all Wegovy dosage strengths to improve affordability and access to match Lilly's efforts for Mounjaro and Zepbound access.Please note that regulatory policies and manufacturer programs regarding these medications continue to evolve. For the most up-to-date information, we recommend consulting current FDA announcements and manufacturer websites.Resources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  33:45
• More Mailbag

  On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright open the mailbag and answer questions from listeners all over the world.Dr. Cooper provides expert insights into complex questions about metabolic health, covering topics including metabolic dysfunction, the effects of chemotherapy on metabolism, a discussion of GLP-1s and those trying to get pregnant and the role of iodine in the diet. Engaging and informative, this episode also arms you with the vocabulary and understanding needed to discuss metabolism with your healthcare provider.Key Takeaways: Metabolic medications like GLP-1s are not just for weight loss; they target the metabolic system, improving fertility and metabolic health. The jury is still out as to whether taking GLP-1s are safe for those trying to become pregnant, but management is possible knowing the half-life of the various GLP-1 drugs. Chemotherapy can impact metabolism; a comprehensive metabolic assessment post-treatment is essential for recovery. Iodine is crucial for thyroid function, and deficiencies may arise from using non-iodized salts; checking iodine levels can guide supplementation. Managing mindset and mechanical eating is essential when using metabolic medications to avoid calorie-counting traps.Personal Stories & Practical Advice: Andrea shares her journey of freeing herself from calorie counting and embracing a healthier mindset. Listeners' questions reflect global engagement and common challenges faced in managing metabolic health.Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  42:18
• The Metabolic Links to PCOS

  On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the intricate metabolic ties to Polycystic Ovarian Syndrome (PCOS). Dr. Cooper provides expert insight into how understanding these links can transform what seems like a permanent condition into a reversible one. “ I feel like there's so much despair around PCOS when it actually doesn't have to be a long-term condition,” says Dr. Cooper. “I know some of that desperation comes from the infertility piece of it… so it's really important to calm down the (metabolic) dysfunction to be successful in fertility.”Key Takeaways: PCOS is often misunderstood as solely an ovarian issue, but it is deeply rooted in neuroendocrine and metabolic imbalances. Diagnosing PCOS involves analyzing menstrual irregularities, androgen levels, and related physical symptoms like hirsutism and acne. Traditional treatments include metformin and spironolactone, but focusing on overall metabolic health can lead to reversal of PCOS symptoms. The importance of comprehensive metabolic health, including regular fueling, sleep quality, and potentially targeting specific metabolic pathways, is emphasized. Misguided advice to lose weight often exacerbates PCOS; instead, enhancing metabolic signals offers a sustainable solution.Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  36:08

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